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Details
Link-It Detail - Disease - Hyperthermia
Debug Stats
  • ### Total Build Time: 72 ms 19.240 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 677 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=32 ms Completed: 32 ms rowSize= 3.383 KB
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 13.665 KB
  • CONCEPT_XREFS gt=11 ms Completed: 11 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hyperthermia C1704628
Definition (1)
A condition that manifests with abnormally high body temperature. In hyperthermic state, the hypothalamic set-point is normal but body temperature increases and overrides the ability to lose heat, resulting from exogenous heat exposure or endogenous heat production, e.g. in heat stroke, malignant hyperthermia, endocrine hyperthermia, or neuroleptic malignant syndrome. The concept does not refer to hyperpyrexia, the state when the hypothalamic set-point is reset at a higher temperature and is physiologically regulated.
Relationships (7)

Relation Types:
diso_​to_​diso : 7


Relationships:
isa : 6
parent_​is_​cdrh : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISOisaimg Elevated Fetal Core Body Temperature C1707900
DISO_to_DISOisaimg Endocrine hyperthermia C0424788
DISO_to_DISOisaimg Fever C0015967
DISO_to_DISOisaimg Hyperthermia in newborn C0410943
DISO_to_DISOisaimg Neurogenic hyperthermia C2316873
DISO_to_DISOisaimg O/E - temperature elevated C0437737
DISO_to_DISOparent_is_cdrhimg Patient Problem C1254481
Genes (12)

Species:
human : 12
SpeciesGeneGeneIdGene NameEvidence
HumanCRLF19244cytokine receptor-like factor 1
img OMIM, Score=833, UMLKSK CUI: C1704628
HumanTP638626tumor protein p63
img OMIM, Score=1000, UMLKSK CUI: C1704628
HumanTRPV17442transient receptor potential cation channel, subfamily V, member 1
img GENERIF, Score=861, Pubmed Id: 18222434, UMLKSK CUI: C1704628
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 12085210, UMLKSK CUI: C1704628
HumanTP537157tumor protein p53
img GENERIF, Score=861, Pubmed Id: 17564316, UMLKSK CUI: C1704628
HumanTNF7124tumor necrosis factor
img GENERIF, Score=861, Pubmed Id: 18581940, UMLKSK CUI: C1704628
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=861, Pubmed Id: 18451164, UMLKSK CUI: C1704628
HumanSOD26648superoxide dismutase 2, mitochondrial
img GENERIF, Score=1000, Pubmed Id: 15512801, UMLKSK CUI: C1704628
HumanRYR16261ryanodine receptor 1 (skeletal)
img OMIM, Score=1000, UMLKSK CUI: C1704628
img GAD, Score=1000, Pubmed Id: 12059893, UMLKSK CUI: C1704628
HumanLIFR3977leukemia inhibitory factor receptor alpha
img OMIM, Score=1000, UMLKSK CUI: C1704628
img OMIM, Score=1000, UMLKSK CUI: C1704628
HumanHSF13297heat shock transcription factor 1
img GENERIF, Score=1000, Pubmed Id: 15358168, UMLKSK CUI: C1704628
HumanEDA1896ectodysplasin A
img OMIM, Score=1000, UMLKSK CUI: C1704628
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1704628Hyperthermia0self