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Genes (449)
Species: human : 440 mouse : 9 | |
Mouse | PAOX | 196743 | polyamine oxidase (exo-N4-amino) | An almost complete prevention of tumor growth was achieved in U-251 human glioblastoma xenografted nude mice, by partial decontamination of the gastrointestinal tract and feeding of a polyamine-free diet containing inhibitors of ornithine decarboxylase (DFMO) and of polyamine oxidase (MDL 72527). | Mouse | GOPC | 57120 | golgi-associated PDZ and coiled-coil motif containing | Here, we show that a glioblastoma-associated, ligand-independent rearrangement product of ROS (FIG-ROS) cooperates with loss of the tumor suppressor gene locus Ink4a;Arf to produce glioblastomas in the mouse. | Mouse | SMOX | 54498 | spermine oxidase | An almost complete prevention of tumor growth was achieved in U-251 human glioblastoma xenografted nude mice, by partial decontamination of the gastrointestinal tract and feeding of a polyamine-free diet containing inhibitors of ornithine decarboxylase (DFMO) and of polyamine oxidase (MDL 72527). | Mouse | HYAL2 | 8692 | hyaluronoglucosaminidase 2 | Similarly, all glioblastomas multiforme expressed hyaluronidases MGEA5 and Hyal2. | Mouse | OSM | 5008 | oncostatin M | Click here to display 3 evidence detail records. | Mouse | MLF1 | 4291 | myeloid leukemia factor 1 | Immunohistochemical analysis of rat F98 and C6 GBM tumor models showed that MLF1IP was highly expressed in the tumor core where it was co-localized with MLF1 and nestin. | Mouse | LGALS3BP | 3959 | lectin, galactoside-binding, soluble, 3 binding protein | Expression levels of the immunostimulatory 90K antigen in mammary carcinoma, glioblastoma, and other tumor-derived cell lines inversely correlate with their tumorigenicity in athymic mice. | Mouse | IL13 | 3596 | interleukin 13 | Three alternate day injections (qod) of IL-13 toxin (250 microg/kg/day) into other subcutaneous U87 glioblastoma tumors also produced durable complete responses (CR) in all 5 mice. This conclusion was made based on (a) time-dependent induction of several proapoptotic molecules, such as caspases (caspase-3, -8, and -9) in tumors; (b) cleavage of procaspase-3 and poly(ADP-ribose) polymerase (PARP); and (c) the release of cytochrome c from mitochondria to the cytosol on injection of IL-13 cytotoxin in U251 glioblastoma tumors established in immunodeficient animals. | Mouse | HIF1A | 3091 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Evaluation of hypoxia-inducible factor-1alpha (HIF-1alpha) as an intrinsic marker of tumor hypoxia in U87 MG human glioblastoma: in vitro and xenograft studies. | Human | SPANXA2 | 728712 | SPANX family, member A2 | Overall SPANXA was the most frequently expressed SPANX variant in melanoma and glioblastoma cell lines. | Human | MAGED4 | 728239 | melanoma antigen family D, 4 | We analyzed the expression of 21 MAGE genes in ten RCC samples and two glioblastoma samples and could identify the first MHC class I ligand NIGDEALIGRW from MAGED4 presented by HLA-A*25 on RCC solid tumor tissue. MAGED4 was expressed in 30% of RCC and both glioblastoma samples. | Human | MIR221 | 407006 | microRNA 221 | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | MIR21 | 406991 | microRNA 21 | Click here to display 4 evidence detail records. | Human | MIR181C | 406957 | microRNA 181c | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | MIR181B2 | 406956 | microRNA 181b-2 | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | MIR181B1 | 406955 | microRNA 181b-1 | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | MIR181A2 | 406954 | microRNA 181a-2 | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | MIR128-2 | 406916 | | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | MIR128-1 | 406915 | | The most interesting results came from miR-221, strongly up-regulated in glioblastoma and from a set of brain-enriched miRNAs, miR-128, miR-181a, miR-181b, and miR-181c, which are down-regulated in glioblastoma. | Human | SPRED3 | 399473 | sprouty-related, EVH1 domain containing 3 | Mutation analysis of CBL-C and SPRED3 on 19q in human glioblastoma. | Human | IL31 | 386653 | interleukin 31 | In the present work, we analyzed the signaling properties of IL-31 in glioblastoma and melanoma tumor cells. | Human | AGRN | 375790 | agrin | Click here to display 3 evidence detail records. | Human | POTED | 317754 | POTE ankyrin domain family, member D | Microarray analysis confirmed and extended to the human T98-G glioblastoma cells, the downregulation of several POTE genes expression by Wy-14,643, a potent PPARalpha activator. | Human | SIRPA | 140885 | signal-regulatory protein alpha | Click here to display 3 evidence detail records. | Human | CST9 | 128822 | cystatin 9 (testatin) | CLM mRNA was barely detected in most tumor cell lines except for breast adenocarcinoma MCF-7 cells and glioblastoma U251 cells, but after LPS or PMA stimulation, CLM expression was increased in myelogenous leukemia cell lines HL-60 and U-937. |
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