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Details
Link-It Detail - Disease - Hypereosinophilic Syndrome
Debug Stats
  • ### Total Build Time: 155 ms 25.061 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 584 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 548 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 560 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 1.508 KB
  • CONCEPT_RELATIONSHIPS gt=107 ms Completed: 107 ms rowSize= 14.133 KB
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 6.055 KB
  • CONCEPT_XREFS gt=11 ms Completed: 11 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hypereosinophilic Syndrome C1540912
Definition (1)
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. It is often referred to as idiopathic.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Eosinophilia C0014457
Children (1)
img Pulmonary Eosinophilia C0034068
Ancestral Roots
RootRoot Plus OneDepthParent
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189395img Eosinophilia C0014457
Relationships (68)

Relation Types:
diso_​to_​anat : 4
diso_​to_​chem : 49
diso_​to_​diso : 10
diso_​to_​gene : 2
diso_​to_​phen : 3


Relationships:
none : 30
gene_​associated_​with_​disease : 2
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​finding_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
isa : 2
mapped_​to : 1
may_​be_​associated_​disease_​of_​disease : 1
may_​treat : 29
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO117img Complication Aspects C1171258
DISO_to_DISO107img Complication Aspects C1171258
DISO_to_PHEN92img genetic aspects C0017399
DISO_to_PHEN71img genetic aspects C0017399
DISO_to_CHEM64img Platelet-Derived Growth Factor alpha Receptor C0290067
DISO_to_CHEM64img Receptor, Platelet-Derived Growth Factor alpha C0290067
DISO_to_CHEM62img Cleavage and Polyadenylation Factor C0110046
DISO_to_CHEM58img Pyrimidines C0034289
DISO_to_CHEM57img Oncogene Proteins, Fusion C0029014
DISO_to_CHEM57img Piperazines C0031958
DISO_to_CHEM56img Pyrimidines C0034289
DISO_to_CHEM53img Piperazines C0031958
DISO_to_ANAT31img Eosinophils C0014467
DISO_to_CHEM31img Platelet-Derived Growth Factor alpha Receptor C0290067
DISO_to_CHEM29img Cleavage and Polyadenylation Factor C0110046
DISO_to_CHEM28img Antineoplastic Agents C0003392
DISO_to_ANAT25img In Blood C0005768
DISO_to_DISO25img Eosinophilia C0014457
DISO_to_ANAT22img In Blood C0005768
DISO_to_CHEM22img Chimeric Oncogene Proteins C0029014
DISO_to_DISO22img Eosinophilia C0014457
DISO_to_CHEM20img Enzyme Inhibitors C0014432
DISO_to_CHEM20img Protein Kinase Inhibitors C1449702
DISO_to_CHEM18img Antibodies, Monoclonal C0003250
DISO_to_CHEM16img Protein Tyrosine Kinase C0033681
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanFIP1L181608factor interacting with PAPOLA and CPSF1
img GENERIF, Score=1000, Pubmed Id: 12660384, UMLKSK CUI: C1540912
img GENERIF, Score=1000, Pubmed Id: 16502585, UMLKSK CUI: C1540912
HumanPDGFRA5156platelet-derived growth factor receptor, alpha polypeptide
img GENERIF, Score=1000, Pubmed Id: 17214097, UMLKSK CUI: C1540912
HumanCCNT1904cyclin T1
INFERRED, Score=800, UMLKSK CUI: C1540912
HumanBIRC5332baculoviral IAP repeat containing 5
img GENERIF, Score=734, Pubmed Id: 16761316, UMLKSK CUI: C1540912
HumanBIRC3330baculoviral IAP repeat containing 3
img GENERIF, Score=734, Pubmed Id: 16761316, UMLKSK CUI: C1540912
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1540912Hypereosinophilic Syndrome0self