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Details
Link-It Detail - Disease - Cellular Stress
Debug Stats
  • ### Total Build Time: 36 ms 40.722 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 328 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 261 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 7.020 KB
  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 31.907 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cellular Stress C1516373
Definition (1)
Cellular or subcellular processes involved with significant disturbance from a homeostatic condition. (NCI)
Relationships (12)

Relation Types:
diso_​to_​chem : 1
diso_​to_​diso : 3
diso_​to_​gene : 2
diso_​to_​phen : 1
diso_​to_​phys : 5


Relationships:
biological_​process_​has_​initiator_​process : 6
biological_​process_​results_​from_​biological_​process : 1
gene_​plays_​role_​in_​process : 2
gene_​product_​plays_​role_​in_​biological_​process : 1
isa : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEMgene_product_plays_role_in_biological_processimg HIF1alpha protein C0965644
DISO_to_DISOisaimg Genotoxic Stress C1257899
DISO_to_DISObiological_process_has_initiator_processimg Inflammation Process C1155266
DISO_to_DISOisaimg Oxidative Stress C0242606
DISO_to_GENEgene_plays_role_in_processimg HIF1A gene C1333897
DISO_to_GENEgene_plays_role_in_processimg HIF1A wt Allele C1704838
DISO_to_PHENbiological_process_has_initiator_processimg Autoregulation C0019868
DISO_to_PHYSbiological_process_has_initiator_processimg Acid-Base Equilibrium C0001117
DISO_to_PHYSbiological_process_has_initiator_processimg Antiinflammatory Effect C1516019
DISO_to_PHYSbiological_process_has_initiator_processimg Cell Death Signaling C1516341
DISO_to_PHYSbiological_process_results_from_biological_processimg Cellular Stress Response C1516374
DISO_to_PHYSbiological_process_has_initiator_processimg Stress Response Signaling C1514991
Genes (41)

Species:
human : 41
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPINK165018PTEN induced putative kinase 1
img GENERIF, Score=1000, Pubmed Id: 17989306, UMLKSK CUI: C1516373
HumanRETN56729resistin
img GENERIF, Score=875, Pubmed Id: 12829623, UMLKSK CUI: C1516373
HumanUGT1A154658UDP glucuronosyltransferase 1 family, polypeptide A1
img GENERIF, Score=913, Pubmed Id: 17259171, UMLKSK CUI: C1516373
HumanPPP1R15A23645protein phosphatase 1, regulatory subunit 15A
img GENERIF, Score=964, Pubmed Id: 17273797, UMLKSK CUI: C1516373
HumanSIRT323410sirtuin 3
img GENERIF, Score=1000, Pubmed Id: 17437997, UMLKSK CUI: C1516373
HumanTAB223118TGF-beta activated kinase 1/MAP3K7 binding protein 2
img GENERIF, Score=673, Pubmed Id: 15590691, UMLKSK CUI: C1516373
HumanCOPS510987COP9 signalosome subunit 5
img GENERIF, Score=1000, Pubmed Id: 15994944, UMLKSK CUI: C1516373
HumanHTATIP210553HIV-1 Tat interactive protein 2, 30kDa
img GENERIF, Score=708, Pubmed Id: 18519672, UMLKSK CUI: C1516373
HumanTAB110454TGF-beta activated kinase 1/MAP3K7 binding protein 1
img GENERIF, Score=673, Pubmed Id: 15590691, UMLKSK CUI: C1516373
HumanKEAP19817kelch-like ECH-associated protein 1
img GENERIF, Score=913, Pubmed Id: 17259171, UMLKSK CUI: C1516373
HumanTRAF49618TNF receptor-associated factor 4
img GENERIF, Score=1000, Pubmed Id: 12788948, UMLKSK CUI: C1516373
HumanALDH4A18659aldehyde dehydrogenase 4 family, member A1
img GENERIF, Score=983, Pubmed Id: 14986171, UMLKSK CUI: C1516373
HumanVCP7415valosin containing protein
img GENERIF, Score=734, Pubmed Id: 16621797, UMLKSK CUI: C1516373
HumanUCP27351uncoupling protein 2 (mitochondrial, proton carrier)
img GENERIF, Score=1000, Pubmed Id: 12960023, UMLKSK CUI: C1516373
HumanUBE2V27336ubiquitin-conjugating enzyme E2 variant 2
img GENERIF, Score=901, Pubmed Id: 14562038, UMLKSK CUI: C1516373
HumanUBE2N7334ubiquitin-conjugating enzyme E2N
img GENERIF, Score=901, Pubmed Id: 14562038, UMLKSK CUI: C1516373
HumanTP537157tumor protein p53
img GENERIF, Score=964, Pubmed Id: 12138209, UMLKSK CUI: C1516373
img GENERIF, Score=1000, Pubmed Id: 12518062, UMLKSK CUI: C1516373
img GENERIF, Score=913, Pubmed Id: 18519672, UMLKSK CUI: C1516373
HumanTNF7124tumor necrosis factor
img GENERIF, Score=983, Pubmed Id: 12553033, UMLKSK CUI: C1516373
HumanMAP3K76885mitogen-activated protein kinase kinase kinase 7
img GENERIF, Score=673, Pubmed Id: 15590691, UMLKSK CUI: C1516373
HumanRB15925retinoblastoma 1
img GENERIF, Score=983, Pubmed Id: 12153616, UMLKSK CUI: C1516373
HumanRAN5901RAN, member RAS oncogene family
img GENERIF, Score=1000, Pubmed Id: 16368437, UMLKSK CUI: C1516373
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 15812311, UMLKSK CUI: C1516373
HumanPRNP5621prion protein
img GENERIF, Score=1000, Pubmed Id: 12392052, UMLKSK CUI: C1516373
img GENERIF, Score=861, Pubmed Id: 16950206, UMLKSK CUI: C1516373
HumanPPP1R105514protein phosphatase 1, regulatory subunit 10
img GENERIF, Score=983, Pubmed Id: 17318220, UMLKSK CUI: C1516373
HumanPIP4K2A5305phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
img GENERIF, Score=964, Pubmed Id: 18364242, UMLKSK CUI: C1516373
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1516373Cellular Stress0self