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Details
Link-It Detail - Disease - DNA Breaks, Double-Stranded
Debug Stats
  • ### Total Build Time: 74 ms 40.266 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 335 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 198 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=50 ms Completed: 50 ms rowSize= 38.080 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
DNA Breaks, Double-Stranded C1511667
Definition (1)
A DNA Double Strand Break involves a disruption of the covalent linkages among the phosphodeoxyribose moieties within the sugar-phosphate backbone in both strands of a DNA molecule.
Semantic Types (1)
Cell or Molecular Dysfunction (T049)
Genes (54)

Species:
human : 54
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanACTR579913ARP5 actin-related protein 5 homolog (yeast)
img GENERIF, Score=771, Pubmed Id: 19014934, UMLKSK CUI: C1511667
HumanNHEJ179840nonhomologous end-joining factor 1
img GENERIF, Score=991, Pubmed Id: 17504121, UMLKSK CUI: C1511667
HumanTDP155775tyrosyl-DNA phosphodiesterase 1
img GENERIF, Score=869, Pubmed Id: 17600775, UMLKSK CUI: C1511667
img GENERIF, Score=869, Pubmed Id: 12023295, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 15647511, UMLKSK CUI: C1511667
HumanNLRP255655NLR family, pyrin domain containing 2
img GENERIF, Score=991, Pubmed Id: 17431132, UMLKSK CUI: C1511667
HumanBBC327113BCL2 binding component 3
img GENERIF, Score=1000, Pubmed Id: 15595728, UMLKSK CUI: C1511667
HumanSETX23064senataxin
img GENERIF, Score=702, Pubmed Id: 17562789, UMLKSK CUI: C1511667
HumanPNKP11284polynucleotide kinase 3'-phosphatase
img GENERIF, Score=991, Pubmed Id: 17638872, UMLKSK CUI: C1511667
HumanCHEK211200checkpoint kinase 2
img GENERIF, Score=892, Pubmed Id: 16905549, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 17030982, UMLKSK CUI: C1511667
HumanRAD5010111RAD50 homolog (S. cerevisiae)
img GENERIF, Score=710, Pubmed Id: 17524422, UMLKSK CUI: C1511667
img GENERIF, Score=694, Pubmed Id: 11809878, UMLKSK CUI: C1511667
img GENERIF, Score=892, Pubmed Id: 12660252, UMLKSK CUI: C1511667
img GENERIF, Score=892, Pubmed Id: 16905549, UMLKSK CUI: C1511667
HumanMDC19656mediator of DNA-damage checkpoint 1
img GENERIF, Score=991, Pubmed Id: 18678890, UMLKSK CUI: C1511667
HumanRECQL49401RecQ protein-like 4
img GENERIF, Score=991, Pubmed Id: 16141230, UMLKSK CUI: C1511667
HumanRNF89025ring finger protein 8, E3 ubiquitin protein ligase
img GENERIF, Score=991, Pubmed Id: 18001824, UMLKSK CUI: C1511667
HumanCCNA18900cyclin A1
img GENERIF, Score=771, Pubmed Id: 15456866, UMLKSK CUI: C1511667
HumanRAD54L8438RAD54-like (S. cerevisiae)
img GENERIF, Score=771, Pubmed Id: 17660833, UMLKSK CUI: C1511667
HumanXRCC57520X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
img GENERIF, Score=991, Pubmed Id: 18936166, UMLKSK CUI: C1511667
HumanXRCC47518X-ray repair complementing defective repair in Chinese hamster cells 4
img GENERIF, Score=991, Pubmed Id: 17963495, UMLKSK CUI: C1511667
HumanXRCC37517X-ray repair complementing defective repair in Chinese hamster cells 3
img GENERIF, Score=991, Pubmed Id: 10541549, UMLKSK CUI: C1511667
HumanXRCC17515X-ray repair complementing defective repair in Chinese hamster cells 1
img GENERIF, Score=762, Pubmed Id: 15498778, UMLKSK CUI: C1511667
HumanXPC7508xeroderma pigmentosum, complementation group C
img GENERIF, Score=991, Pubmed Id: 18089819, UMLKSK CUI: C1511667
HumanWRN7486Werner syndrome, RecQ helicase-like
img GENERIF, Score=734, Pubmed Id: 18524993, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 17875398, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 15733840, UMLKSK CUI: C1511667
HumanTP53BP17158tumor protein p53 binding protein 1
img GENERIF, Score=860, Pubmed Id: 15525939, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 19064641, UMLKSK CUI: C1511667
img GENERIF, Score=734, Pubmed Id: 17940005, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 17043355, UMLKSK CUI: C1511667
img GENERIF, Score=991, Pubmed Id: 12824158, UMLKSK CUI: C1511667
HumanTP537157tumor protein p53
img GENERIF, Score=991, Pubmed Id: 16872365, UMLKSK CUI: C1511667
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=991, Pubmed Id: 15928077, UMLKSK CUI: C1511667
HumanTERF27014telomeric repeat binding factor 2
img GENERIF, Score=991, Pubmed Id: 18025071, UMLKSK CUI: C1511667
HumanSRSF16426serine/arginine-rich splicing factor 1
img GENERIF, Score=991, Pubmed Id: 16096057, UMLKSK CUI: C1511667
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1511667DNA Breaks, Double-Stranded0self