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Details
Link-It Detail - Disease - DNA Crosslink
Debug Stats
  • ### Total Build Time: 51 ms 14.364 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 244 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=34 ms Completed: 34 ms rowSize= 8.834 KB
  • CONCEPT_GENES gt=9 ms Completed: 9 ms rowSize= 3.758 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
DNA Crosslink C1511665
Definition (1)
DNA Crosslinking involves the formation of a covalent bond between two bases on DNA. (NCI)
Relationships (16)

Relation Types:
diso_​to_​anat : 1
diso_​to_​chem : 12
diso_​to_​diso : 2
diso_​to_​phys : 1


Relationships:
biological_​process_​results_​from_​biological_​process : 1
chemical_​or_​drug_​has_​mechanism_​of_​action : 5
chemical_​or_​drug_​has_​physiologic_​effect : 6
chemical_​or_​drug_​initiates_​biological_​process : 1
is_​location_​of_​biological_​process : 1
isa : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_location_of_biological_processimg Chromosome Structures C0729606
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide C0045644
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg 8,8'-[[(propane-1,3-diyl)dioxy]bis[(11aS)-7-methoxy-2-methylidene-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one] C1519143
DISO_to_CHEMchemical_or_drug_has_mechanism_of_actionimg BIZELESIN C0209891
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg Bi-functional Alkylating Agent VAL-083 C3274620
DISO_to_CHEMchemical_or_drug_has_mechanism_of_actionimg DACH Polymer Platinate AP5346 C2745883
DISO_to_CHEMchemical_or_drug_initiates_biological_processimg DNA Crosslinker C1511666
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg DNA Minor Groove Binding Agent PM01183 C2826135
DISO_to_CHEMchemical_or_drug_has_mechanism_of_actionimg L-NDDP C0125061
DISO_to_CHEMchemical_or_drug_has_mechanism_of_actionimg Liposomal Oxaliplatin C1831940
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg RH1 C0764430
DISO_to_CHEMchemical_or_drug_has_mechanism_of_actionimg oxaliplatin C0069717
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg penclomedine C0070220
DISO_to_DISOisaimg DNA Interstrand Crosslinking C1511674
DISO_to_DISOisaimg DNA Intrastrand Crosslinking C1511675
DISO_to_PHYSbiological_process_results_from_biological_processimg DNA Damage Repair C0012899
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanNBN4683nibrin
img GENERIF, Score=734, Pubmed Id: 12447395, UMLKSK CUI: C1511665
HumanMLH14292mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
img GENERIF, Score=896, Pubmed Id: 18787700, UMLKSK CUI: C1511665
HumanFANCD22177Fanconi anemia, complementation group D2
img GENERIF, Score=734, Pubmed Id: 12447395, UMLKSK CUI: C1511665
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1511665DNA Crosslink0self