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Details
Link-It Detail - Disease - Angiogenic Switch
Debug Stats
  • ### Total Build Time: 8 ms 11.765 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 291 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 3.274 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 6.660 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Angiogenic Switch C1510885
Definition (1)
Loss of the balance between stimulation and inhibition of new blood vessel growth. A required early step in cancer growth and metastasis.
Relationships (4)

Relation Types:
diso_​to_​anat : 1
diso_​to_​diso : 2
diso_​to_​phys : 1


Relationships:
anatomy_​originated_​from_​biological_​process : 1
biological_​process_​results_​from_​biological_​process : 1
process_​includes_​biological_​process : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATanatomy_originated_from_biological_processimg Blood Vessel C0005847
DISO_to_DISOprocess_includes_biological_processimg Tumor Angiogenesis C1519670
DISO_to_DISOprocess_includes_biological_processimg Tumor Progression C0178874
DISO_to_PHYSbiological_process_results_from_biological_processimg Tumor Oxygenation C1519687
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanFGFBP19982fibroblast growth factor binding protein 1
img GENERIF, Score=734, Pubmed Id: 16324873, UMLKSK CUI: C1510885
HumanPTTG19232pituitary tumor-transforming 1
img GENERIF, Score=1000, Pubmed Id: 16394085, UMLKSK CUI: C1510885
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=901, Pubmed Id: 14983012, UMLKSK CUI: C1510885
img GENERIF, Score=901, Pubmed Id: 18273500, UMLKSK CUI: C1510885
HumanTRPC47223transient receptor potential cation channel, subfamily C, member 4
img GENERIF, Score=1000, Pubmed Id: 18021253, UMLKSK CUI: C1510885
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 14707264, UMLKSK CUI: C1510885
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1510885Angiogenic Switch0self