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Details
Link-It Detail - Disease - Differentiated Thyroid Cancer
Debug Stats
  • ### Total Build Time: 32 ms 71.041 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 356 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 405 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=8 ms Completed: 8 ms rowSize= 14.428 KB
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 54.637 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.163 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Differentiated Thyroid Cancer C1337013
Definition (1)
An adenocarcinoma arising from the thyroid gland showing extensive evidence of follicular cell differentiation. According to the nuclear features of the malignant follicular cells, it is classified either as papillary, or follicular carcinoma. (NCI05)
Relationships (37)

Relation Types:
diso_​to_​anat : 22
diso_​to_​diso : 15


Relationships:
is_​abnormal_​cell_​of_​disease : 9
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 4
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 3
isa : 8
may_​be_​finding_​of_​disease : 2
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Adenocarcinoma Cell C1510779
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Endocrine System C0014136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Head and neck structure C0460004
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Endocrine Cell C1518172
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Thyroid Follicular Cell C1512971
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Neck C0027530
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Endocrine Cell C1513951
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Structure of thyroid follicle C0229577
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Thyroid Gland C0040132
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Thyroid Gland Epithelial Tissue C1710410
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Thyroid Gland Follicular Cell C1181052
DISO_to_DISOisaimg Adenocarcinoma, Follicular C0206682
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOmay_be_finding_of_diseaseimg Cold Nodule C1333077
Genes (35)

Species:
human : 35
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPTTG19232pituitary tumor-transforming 1
img NCI, Score=801, Pubmed Id: 12727994, UMLKSK CUI: C1337013
img GENERIF, Score=1000, Pubmed Id: 12727994, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 12727994, UMLKSK CUI: C1337013
img GENERIF, Score=1000, Pubmed Id: 17297475, UMLKSK CUI: C1337013
HumanWNT5A7474wingless-type MMTV integration site family, member 5A
img GENERIF, Score=988, Pubmed Id: 15735754, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 15735754, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 15735754, UMLKSK CUI: C1337013
HumanTPO7173thyroid peroxidase
img NCI, Score=801, Pubmed Id: 8710531, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 9329585, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8732452, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8691351, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8574299, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8117301, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8691351, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8157713, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11198265, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8530612, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 10470226, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8530612, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 15170676, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11198265, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8691639, UMLKSK CUI: C1337013
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
img GENERIF, Score=988, Pubmed Id: 12144133, UMLKSK CUI: C1337013
HumanTNF7124tumor necrosis factor
img GENERIF, Score=988, Pubmed Id: 12144133, UMLKSK CUI: C1337013
HumanNKX2-17080
img NCI, Score=801, Pubmed Id: 11508827, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8691351, UMLKSK CUI: C1337013
HumanTHBS17057thrombospondin 1
img GENERIF, Score=1000, Pubmed Id: 18661355, UMLKSK CUI: C1337013
HumanTG7038thyroglobulin
img GENERIF, Score=988, Pubmed Id: 17671725, UMLKSK CUI: C1337013
HumanSOD26648superoxide dismutase 2, mitochondrial
img NCI, Score=801, Pubmed Id: 15887859, UMLKSK CUI: C1337013
HumanSLC5A56528solute carrier family 5 (sodium/iodide cotransporter), member 5
img GENERIF, Score=1000, Pubmed Id: 15968416, UMLKSK CUI: C1337013
HumanRET5979ret proto-oncogene
img GENERIF, Score=895, Pubmed Id: 17270245, UMLKSK CUI: C1337013
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
img GENERIF, Score=892, Pubmed Id: 16288007, UMLKSK CUI: C1337013
HumanSLC26A45172solute carrier family 26 (anion exchanger), member 4
img NCI, Score=801, Pubmed Id: 11454507, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11454507, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 15170676, UMLKSK CUI: C1337013
HumanTNFRSF11B4982tumor necrosis factor receptor superfamily, member 11b
img NCI, Score=801, Pubmed Id: 15746993, UMLKSK CUI: C1337013
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 11502841, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11502841, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11502841, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11502841, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 8394105, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 11502841, UMLKSK CUI: C1337013
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 18664479, UMLKSK CUI: C1337013
HumanMCM74176minichromosome maintenance complex component 7
img NCI, Score=801, Pubmed Id: 16547620, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 16547620, UMLKSK CUI: C1337013
HumanKRT163868keratin 16
img NCI, Score=801, Pubmed Id: 9428928, UMLKSK CUI: C1337013
HumanIGF1R3480insulin-like growth factor 1 receptor
img GENERIF, Score=988, Pubmed Id: 14973173, UMLKSK CUI: C1337013
HumanID13397inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 15579766, UMLKSK CUI: C1337013
img GENERIF, Score=1000, Pubmed Id: 15579766, UMLKSK CUI: C1337013
HumanHLA-C3107
img NCI, Score=801, Pubmed Id: 14716759, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 14716759, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 14716759, UMLKSK CUI: C1337013
img GENERIF, Score=1000, Pubmed Id: 14716759, UMLKSK CUI: C1337013
HumanGRK52869G protein-coupled receptor kinase 5
img NCI, Score=801, Pubmed Id: 12107237, UMLKSK CUI: C1337013
img NCI, Score=801, Pubmed Id: 12107237, UMLKSK CUI: C1337013
HumanFGF22247fibroblast growth factor 2 (basic)
img GENERIF, Score=1000, Pubmed Id: 12727994, UMLKSK CUI: C1337013
HumanETS12113v-ets avian erythroblastosis virus E26 oncogene homolog 1
img NCI, Score=801, Pubmed Id: 15879365, UMLKSK CUI: C1337013
HumanERBB32065v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
img GENERIF, Score=1000, Pubmed Id: 18424286, UMLKSK CUI: C1337013
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1337013Differentiated Thyroid Cancer0self