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Details
Link-It Detail - Disease - Germ Cell Neoplasm of Testis
Debug Stats
  • ### Total Build Time: 54 ms 57.685 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 354 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 289 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=21 ms Completed: 21 ms rowSize= 14.335 KB
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 41.489 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Germ Cell Neoplasm of Testis C1336708
Definition (1)
A germ cell tumor arising from the testis. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor.
Relationships (34)

Relation Types:
diso_​to_​anat : 9
diso_​to_​diso : 25


Relationships:
alias_​of : 1
inheritance_​type_​of : 1
is_​abnormal_​cell_​of_​disease : 2
is_​associated_​anatomic_​site_​of : 4
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
isa : 4
manifestation_​of : 14
related_​to : 5
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Germ Cells C0017471
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Germinal Layer C1708239
DISO_to_ANATis_associated_anatomic_site_ofimg Gonadal structure C0018067
DISO_to_ANATis_associated_anatomic_site_ofimg Male Reproductive System C1963704
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Germ Cell C1513971
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Sex Cord-Stromal Cell C1514083
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_associated_anatomic_site_ofimg Testis C0039597
DISO_to_DISOmanifestation_ofimg Azospermia/oligospermia (present at diagnosis) C1848895
DISO_to_DISOisaimg Childhood Testicular Germ Cell Neoplasm C0796663
DISO_to_DISOrelated_toimg EMBRYONAL CELL CARCINOMA C3463918
DISO_to_DISOmanifestation_ofimg Elevated AFP (endodermal sinus tumor) C1848893
DISO_to_DISOmanifestation_ofimg Elevated hCG (choriocarcinoma) C1848892
DISO_to_DISOmanifestation_ofimg Elevated hCG or AFP or both (embryonal carcinoma) C1848894
DISO_to_DISOrelated_toimg Endodermal Sinus Tumor C0014145
DISO_to_DISOalias_ofimg Germ Cell Neoplasm of Testis C1336708
DISO_to_DISOrelated_toimg Germ cell tumor, nonseminomatous (morphologic abnormality) C1266158
DISO_to_DISOmanifestation_ofimg Highest incidence in men of European descent C1848899
DISO_to_DISOmanifestation_ofimg Isochromosome 12p (i(12p)) C1848891
DISO_to_DISOinheritance_type_ofimg Isolated cases C1853237
DISO_to_DISOmanifestation_ofimg Male germ cell tumors (GCT), 2 subtypes - C1848889
DISO_to_DISOmanifestation_ofimg Most common cancer in men aged 15-40 years C1848898
DISO_to_DISOmanifestation_ofimg Nonseminoma (embryonal carcinoma, teratoma, choriocarcinoma, endodermal sinus tumor) C1848890
DISO_to_DISOmanifestation_ofimg Occasionally germ cell tumor arise from extra gonadal site (e.g., mediastinum, retroperitoneum, pineal gland) C1848897
Genes (85)

Species:
human : 85
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSPANXB1728695SPANX family, member B1
img NCI, Score=801, Pubmed Id: 16390498, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 17204091, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 17204091, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 16390498, UMLKSK CUI: C1336708
HumanPOU5F1P3642559POU class 5 homeobox 1 pseudogene 3
img GENERIF, Score=926, Pubmed Id: 16557044, UMLKSK CUI: C1336708
HumanERVK7449619
img NCI, Score=801, Pubmed Id: 11810253, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 9474889, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 9524581, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 10969740, UMLKSK CUI: C1336708
HumanMIR373442918microRNA 373
img GENERIF, Score=988, Pubmed Id: 17695719, UMLKSK CUI: C1336708
HumanMIR372442917microRNA 372
img GENERIF, Score=988, Pubmed Id: 17695719, UMLKSK CUI: C1336708
HumanDPPA3359787developmental pluripotency associated 3
img NCI, Score=801, Pubmed Id: 14684992, UMLKSK CUI: C1336708
HumanNLRP7199713NLR family, pyrin domain containing 7
img NCI, Score=801, Pubmed Id: 15596043, UMLKSK CUI: C1336708
HumanINHBE83729inhibin, beta E
img NCI, Score=801, Pubmed Id: 9365168, UMLKSK CUI: C1336708
HumanNANOG79923Nanog homeobox
img NCI, Score=801, Pubmed Id: 15982323, UMLKSK CUI: C1336708
HumanBIRC779444baculoviral IAP repeat containing 7
img GENERIF, Score=723, Pubmed Id: 18515985, UMLKSK CUI: C1336708
HumanERVK664006
img NCI, Score=801, Pubmed Id: 11810253, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 10969740, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 9524581, UMLKSK CUI: C1336708
HumanERVK460359
img NCI, Score=801, Pubmed Id: 10969740, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 11810253, UMLKSK CUI: C1336708
HumanERVK560358
img NCI, Score=801, Pubmed Id: 10969740, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 11810253, UMLKSK CUI: C1336708
HumanTGCT150830testicular germ cell tumor susceptibility 1
img NCI, Score=801, Pubmed Id: 12629412, UMLKSK CUI: C1336708
HumanKLK1443847kallikrein-related peptidase 14
img NCI, Score=801, Pubmed Id: 12752266, UMLKSK CUI: C1336708
HumanPRSS5029122protease, serine, 50
img NCI, Score=801, Pubmed Id: 15491742, UMLKSK CUI: C1336708
HumanKLK1326085kallikrein-related peptidase 13
img NCI, Score=801, Pubmed Id: 12752266, UMLKSK CUI: C1336708
HumanKLK525818kallikrein-related peptidase 5
img NCI, Score=801, Pubmed Id: 12752266, UMLKSK CUI: C1336708
HumanCHEK211200checkpoint kinase 2
img NCI, Score=801, Pubmed Id: 11593395, UMLKSK CUI: C1336708
HumanPRSS2110942protease, serine, 21 (testisin)
img NCI, Score=801, Pubmed Id: 15685234, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 10397266, UMLKSK CUI: C1336708
HumanPNMA210687paraneoplastic Ma antigen 2
img NCI, Score=801, Pubmed Id: 11160472, UMLKSK CUI: C1336708
HumanMVP9961major vault protein
img NCI, Score=801, Pubmed Id: 15154630, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 15154630, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 12644825, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 15154630, UMLKSK CUI: C1336708
img NCI, Score=801, Pubmed Id: 15154630, UMLKSK CUI: C1336708
HumanMDC19656mediator of DNA-damage checkpoint 1
img GENERIF, Score=988, Pubmed Id: 17546051, UMLKSK CUI: C1336708
HumanPLAA9373phospholipase A2-activating protein
img NCI, Score=801, Pubmed Id: 8653285, UMLKSK CUI: C1336708
HumanPIWIL19271piwi-like RNA-mediated gene silencing 1
img NCI, Score=801, Pubmed Id: 12037681, UMLKSK CUI: C1336708
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1336708Germ Cell Neoplasm of Testis0self