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Details
Link-It Detail - Disease - Precursor Lymphoblastic Leukemia/Lymphoma
Debug Stats
  • ### Total Build Time: 80 ms 36.907 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 380 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 502 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=53 ms Completed: 53 ms rowSize= 10.893 KB
  • CONCEPT_GENES gt=23 ms Completed: 23 ms rowSize= 23.908 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.175 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Precursor Lymphoblastic Leukemia/Lymphoma C1335469
Definition (1)
A neoplasm of immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage. Neoplasms involving the bone marrow and the peripheral blood are called precursor lymphoblastic leukemias or acute lymphoblastic leukemias. Neoplasms involving primarily lymph nodes or extranodal sites are called lymphoblastic lymphomas. -- 2003
Relationships (22)

Relation Types:
diso_​to_​anat : 13
diso_​to_​diso : 9


Relationships:
is_​abnormal_​cell_​of_​disease : 5
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 5
may_​be_​finding_​of_​disease : 2
may_​be_​molecular_​abnormality_​of_​disease : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical Lymphoblast C0333826
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Lymphatic System C0024235
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lymphatic Tissue C0024296
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Myeloid Cells C0887899
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Lymphocyte C1514011
DISO_to_ANATis_normal_cell_origin_of_diseaseimg lymphoblast C0229613
DISO_to_DISOisaimg Acute lymphocytic leukemia C0023449
DISO_to_DISOisaimg B Lymphoblastic Leukemia/Lymphoma C0862030
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg Clonal T-Cell Receptor Beta Chain Gene Rearrangement C1516678
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg Clonal T-Cell Receptor Gamma Chain Gene Rearrangement C1516679
DISO_to_DISOisaimg Cutaneous Precursor Lymphoblastic Lymphoma/Leukemia C1707590
DISO_to_DISOmay_be_finding_of_diseaseimg Enlarged Liver C0019209
DISO_to_DISOmay_be_finding_of_diseaseimg Lymphadenopathy C0497156
DISO_to_DISOisaimg Precursor T Lymphoblastic Leukemia/Lymphoma C1301359
DISO_to_DISOisaimg Precursor cell lymphoblastic lymphoma C0079748
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanFADD8772Fas (TNFRSF6)-associated via death domain
img NCI, Score=801, Pubmed Id: 9375749, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 9375749, UMLKSK CUI: C1335469
HumanVCAM17412vascular cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 7680000, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 7680000, UMLKSK CUI: C1335469
HumanUNG7374uracil-DNA glycosylase
img NCI, Score=801, Pubmed Id: 3474482, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 3474482, UMLKSK CUI: C1335469
HumanPTPN135783protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
img NCI, Score=801, Pubmed Id: 9375749, UMLKSK CUI: C1335469
HumanMPL4352myeloproliferative leukemia virus oncogene
img NCI, Score=801, Pubmed Id: 8751457, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 8960108, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 8960108, UMLKSK CUI: C1335469
HumanID33399inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 8632670, UMLKSK CUI: C1335469
HumanID23398inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 8632670, UMLKSK CUI: C1335469
HumanEPHB42050EPH receptor B4
img NCI, Score=801, Pubmed Id: 10221518, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 10221518, UMLKSK CUI: C1335469
HumanEFNB21948ephrin-B2
img NCI, Score=801, Pubmed Id: 10221518, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 10221518, UMLKSK CUI: C1335469
HumanCSF1R1436colony stimulating factor 1 receptor
img NCI, Score=801, Pubmed Id: 14654075, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 14654075, UMLKSK CUI: C1335469
HumanCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
img NCI, Score=801, Pubmed Id: 9639410, UMLKSK CUI: C1335469
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
img NCI, Score=801, Pubmed Id: 9639410, UMLKSK CUI: C1335469
HumanTNFSF8944tumor necrosis factor (ligand) superfamily, member 8
img NCI, Score=801, Pubmed Id: 7528856, UMLKSK CUI: C1335469
img NCI, Score=801, Pubmed Id: 7528856, UMLKSK CUI: C1335469
HumanAXL558AXL receptor tyrosine kinase
img NCI, Score=801, Pubmed Id: 8656672, UMLKSK CUI: C1335469
HumanANXA8L2244annexin A8-like 2
img NCI, Score=801, Pubmed Id: 8231235, UMLKSK CUI: C1335469
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1335469Precursor Lymphoblastic Leukemia/Lymphoma0self