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Details
Link-It Detail - Disease - Nodular Lymphocyte Predominant Hodgkin Lymphoma
Debug Stats
  • ### Total Build Time: 13 ms 21.826 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 392 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 699 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 19.406 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Nodular Lymphocyte Predominant Hodgkin Lymphoma C1334968
Definition (1)
A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse, polymorphous proliferation of scattered large neoplastic cells known as popcorn or L&H cells; the L&H cells are CD15 negative, and rarely positive for CD30 antigen. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II); the prognosis of patients with stage I and stage II disease is very good. Advanced stages have an unfavorable prognosis.
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanIGK@50802
img NCI, Score=801, Pubmed Id: 16049307, UMLKSK CUI: C1334968
HumanSWAP7023075SWAP switching B-cell complex 70kDa subunit
img NCI, Score=801, Pubmed Id: 15163014, UMLKSK CUI: C1334968
HumanCFLAR8837CASP8 and FADD-like apoptosis regulator
img GENERIF, Score=1000, Pubmed Id: 15354734, UMLKSK CUI: C1334968
HumanTRAF17185TNF receptor-associated factor 1
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C1334968
HumanREL5966v-rel avian reticuloendotheliosis viral oncogene homolog
img NCI, Score=801, Pubmed Id: 15551733, UMLKSK CUI: C1334968
img GENERIF, Score=1000, Pubmed Id: 15551733, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 15551733, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 15551733, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 15551733, UMLKSK CUI: C1334968
HumanPOU2F25452POU class 2 homeobox 2
img NCI, Score=801, Pubmed Id: 16648862, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 12647220, UMLKSK CUI: C1334968
HumanPDCD15133programmed cell death 1
img GENERIF, Score=1000, Pubmed Id: 18594468, UMLKSK CUI: C1334968
HumanPAX55079paired box 5
img NCI, Score=801, Pubmed Id: 15339680, UMLKSK CUI: C1334968
img NCI, Score=801, Pubmed Id: 12647220, UMLKSK CUI: C1334968
HumanIGL@3535
img NCI, Score=801, Pubmed Id: 16049307, UMLKSK CUI: C1334968
HumanMS4A1931membrane-spanning 4-domains, subfamily A, member 1
img NCI, Score=801, Pubmed Id: 12393409, UMLKSK CUI: C1334968
HumanBCL6604B-cell CLL/lymphoma 6
img GENERIF, Score=1000, Pubmed Id: 15339680, UMLKSK CUI: C1334968
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1334968Nodular Lymphocyte Predominant Hodgkin Lymphoma0self