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Details
Link-It Detail - Disease - Carcinoma, Islet Cell
Debug Stats
  • ### Total Build Time: 32 ms 46.728 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 400 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 410 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 988 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 1.792 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 6.605 KB
  • CONCEPT_RELATIONSHIPS gt=10 ms Completed: 10 ms rowSize= 15.369 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 19.840 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Carcinoma, Islet Cell C1328479
Pancreatic Endocrine Carcinoma
Definition (1)
A primary malignant neoplasm of the pancreatic ISLET CELLS. Usually it involves the non-INSULIN-producing cell types, the PANCREATIC ALPHA CELLS and the pancreatic delta cells (SOMATOSTATIN-SECRETING CELLS) in GLUCAGONOMA and SOMATOSTATINOMA, respectively.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Pancreatic Neoplasms C0030297
img Adenocarcinoma C0001418
Children (4)
img Glucagonoma C0017689
img Somatostatinoma C0037661
img Vipoma C0011993
img Gastrinoma C0017150
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Site C00276535img Pancreatic Neoplasms C0030297
img Endocrine System Diseases C0014130img Endocrine Gland Neoplasms C00141324img Pancreatic Neoplasms C0030297
img Digestive System Diseases C0012242img Digestive System Neoplasms C00122434img Pancreatic Neoplasms C0030297
img Digestive System Diseases C0012242img Pancreatic Diseases C00302864img Pancreatic Neoplasms C0030297
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Adenocarcinoma C0001418
Relationships (52)

Relation Types:
diso_​to_​anat : 20
diso_​to_​chem : 2
diso_​to_​diso : 28
diso_​to_​phen : 2


Relationships:
none : 14
associated_​with : 1
classifies : 1
is_​abnormal_​cell_​of_​disease : 8
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 6
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 5
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 2
location_​of : 1
mapped_​to : 3
may_​treat : 2
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO75img Pancreatic Neoplasm C0030297
DISO_to_DISO53img Pancreatic Neoplasm C0030297
DISO_to_DISO12img Adenoma, Islet Cell C0022134
DISO_to_PHEN12img genetic aspects C0017399
DISO_to_DISO11img Adenoma, Islet Cell C0022134
DISO_to_DISO10img Complication Aspects C1171258
DISO_to_PHEN10img genetic aspects C0017399
DISO_to_DISO9img Liver Neoplasms C0023903
DISO_to_ANAT6img Blood supply aspects C0005839
DISO_to_DISO6img Carcinoma, Ductal, Pancreatic C0887833
DISO_to_DISO6img Insulinoma C0021670
DISO_to_ANAT5img Islets of Langerhans C0022131
DISO_to_DISO5img Complication Aspects C1171258
DISO_to_DISO5img Insulinoma C0021670
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Endocrine System C0014136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Enteroendocrine Cell C0524979
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Islet Cell C1522529
DISO_to_ANATlocation_ofimg Islets of Langerhans C0022131
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Endocrine Cell C1518172
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Neuroendocrine Cell C1518216
Genes (28)

Species:
human : 28
Page Size
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SpeciesGeneGeneIdGene NameEvidence
HumanMAFA389692v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanGATA5140628GATA binding protein 5
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanTERC7012telomerase RNA component
img NCI, Score=801, Pubmed Id: 9524757, UMLKSK CUI: C1328479
HumanSYP6855synaptophysin
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanSSTR56755somatostatin receptor 5
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanSCTR6344secretin receptor
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanPTPRN5798protein tyrosine phosphatase, receptor type, N
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanPRKCA5578protein kinase C, alpha
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanPAK25062p21 protein (Cdc42/Rac)-activated kinase 2
img NCI, Score=801, Pubmed Id: 2161375, UMLKSK CUI: C1328479
HumanPAK15058p21 protein (Cdc42/Rac)-activated kinase 1
img NCI, Score=801, Pubmed Id: 2161375, UMLKSK CUI: C1328479
HumanNMB4828neuromedin B
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanMEN14221multiple endocrine neoplasia I
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanPDX13651pancreatic and duodenal homeobox 1
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanIGF1R3480insulin-like growth factor 1 receptor
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanIAPP3375islet amyloid polypeptide
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanHES13280hairy and enhancer of split 1, (Drosophila)
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanGHRH2691growth hormone releasing hormone
img NCI, Score=801, Pubmed Id: 6090497, UMLKSK CUI: C1328479
HumanGATA62627GATA binding protein 6
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanGATA42626GATA binding protein 4
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanGAST2520gastrin
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanERBB22064v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanEPHA12041EPH receptor A1
img NCI, Score=801, Pubmed Id: 12370823, UMLKSK CUI: C1328479
HumanCXADR1525coxsackie virus and adenovirus receptor
INFERRED, Score=800, UMLKSK CUI: C1328479
HumanCHGB1114chromogranin B (secretogranin 1)
INFERRED, Score=800, UMLKSK CUI: C1328479
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1328479Carcinoma, Islet Cell0self