Human | RETN | 56729 | resistin | in type 2 diabetic patients, resistin level was not correlated with parameters related to metabolic abnormality and had no significant effect on cardiovascular events |
Human | UTS2 | 10911 | urotensin 2 | Urotensin blood levels are the third factor in rank, after age and diabetes, explaining the incidence of cardiovascular events in end-stage kidney failure |
Human | CLOCK | 9575 | clock circadian regulator | peripheral clock in vascular endothelial cells regulates TM gene expression and that the oscillation of TM expression may contribute to the circadian variation of cardiovascular events |
Human | GDF15 | 9518 | growth differentiation factor 15 | There is a possible role for macrophage-inhibiting cytokine-1 (MIC-1) in coronary artery cardiovascular events |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | Lower levels of adiponectin are associated with a lower risk for the development of new cardiovascular events in patients with clinical evident vascular diseases predictive value of serum adiponectin levels and 8 adiponectin gene polymorphisms for mortality, cardiovascular events and end-stage renal disease in type I diabetic patients A low plasma adiponectin level,was a significant risk factor for the development of cardiovascular events in these Korean patients with type 2 diabetes |
Human | PLA2G7 | 7941 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | The aim of the present study was to evaluate the contribution of the PAFAH gene Arg92His, Ile198Thr and Ala379Val polymorphisms to resistance toward developing cardiovascular events in healthy Sicilian octogenarians Lp-PLA2 is independently associated with progression of cardiac allograft vasculopathy and predicts a higher incidence of cardiovascular events and cardiovascular death in transplant patients |
Human | TLR4 | 7099 | toll-like receptor 4 | Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events; carriers of the allele had significantly more benefit from pravastatin |
Human | THBD | 7056 | thrombomodulin | peripheral clock in vascular endothelial cells regulates TM gene expression and that the oscillation of TM expression may contribute to the circadian variation of cardiovascular events |
Human | SREBF2 | 6721 | sterol regulatory element binding transcription factor 2 | a common variation in the SREBP-2 gene is related with early-stage carotid atherosclerosis in subjects with a risk of cardiovascular events without detectable change in plasma lipid levels |
Human | S100A9 | 6280 | S100 calcium binding protein A9 | MRP-14 expression increases before ST-segment-elevation myocardial infarction (STEMI), and increasing plasma concentrations of MRP-8/14 among healthy individuals predict the risk of future cardiovascular events |
Human | PPARG | 5468 | peroxisome proliferator-activated receptor gamma | The PPARG thymine 1431 allele is associated with a high probility of a nonfatal cardiovascular event before age 70 and is also associated with all-cause mortality in a type 2 diabetic population We conclude that P12A and C161T polymorphisms of the PPAR-gamma gene are important predictors of cardiovascular event in patients with diabetic nephropathy |
Human | PPARA | 5465 | peroxisome proliferator-activated receptor alpha | a L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Sympathetic nerve activity (SNA) in an aging subject leads to an increase in the activity of PAI-1, which indicates that an altered interaction between SNA and PAI-1 activity contributes to increased cardiovascular events in the elderly population |
Human | NPPB | 4879 | natriuretic peptide B | in patients with coronary artery disease, combined use of NT-proBNP (N-terminal-probrain natriuretic peptide ) and hsCRP (high sensitivity C reactive protein) significantly increased predictive value for future cardiovascular events |
Human | MTR | 4548 | 5-methyltetrahydrofolate-homocysteine methyltransferase | Title:Effect of heterozygosity for the methionine synthase 2756 A-->G mutation on the risk for recurrent cardiovascular events.|Association:Not Found|Conclusion:This mutation significantly reduced the risk for recurrent cardiovascular events and elevated red blood cell folate levels. |
Human | MSR1 | 4481 | macrophage scavenger receptor 1 | SR-A gene expression level in the PBMCs specifically increases in patients with acute coronary syndrome, and provides a predictive marker for a reattack of a cardiovascular event |
Human | MPO | 4353 | myeloperoxidase | in patients with acute coronary syndromes, MPO serum levels powerfully predict an increased risk for subsequent cardiovascular events; MPO may serve as both a marker and mediator of vascular inflammation Myeloperoxidase polymorphism related to cardiovascular events in coronary artery disease |
Human | JAK2 | 3717 | Janus kinase 2 | study concludes that JAK2 617V>F homozygosity identifies polycythemia vera or essential thrombocythemia(ET) patients with a more symptomatic myeloproliferative disorder & is associated with a higher risk of major cardiovascular events in patients with ET |
Human | IL18 | 3606 | interleukin 18 (interferon-gamma-inducing factor) | serum interleukin-18 is expressed in patients experiencing cardiovascular events |
Human | IL10 | 3586 | interleukin 10 | IL-10 concentration was associated with an increased risk for future cardiovascular events in post-menopausal women with established coronary atherosclerosis IL-10 reflects a proinflammatory state in patients with ACS and therefore suggests that IL-10 is as effective a biomarker for the risk prediction of future cardiovascular events as other markers of systemic inflammation |
Human | ICAM1 | 3383 | intercellular adhesion molecule 1 | Lys56Met and Gly241Arg ICAM-1 gene variants may have a role in cardiovascular events |
Human | HLA-DRB1 | 3123 | | Increased risk of cardiovascular events (CV) was associated with CRP level, ESR, and HLA-DRB1, suggesting high inflammatory response in genetically predisposed individuals promotes an increased risk of CV events and mortality in rheumatoid arthritis |
Human | GCLC | 2729 | glutamate-cysteine ligase, catalytic subunit | GCLC T allele, together with hypertension and male sex, is associated with cardiovascular events in our study population |
Human | F2RL2 | 2151 | coagulation factor II (thrombin) receptor-like 2 | F2R genetic variants may influence the natural history of CHD in patients at high risk of cardiovascular events |
Human | CYP2C19 | 1557 | cytochrome P450, family 2, subfamily C, polypeptide 19 | Among patients with an acute myocardial infarction who were receiving clopidogrel, those carrying CYP2C19 loss-of-function alleles had a higher rate of subsequent cardiovascular events than those who were not |