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Details
Link-It Detail - Disease - Papillary Renal Cell Carcinoma
Debug Stats
  • ### Total Build Time: 28 ms 74.676 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 358 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 668 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=8 ms Completed: 8 ms rowSize= 14.661 KB
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 57.778 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Papillary Renal Cell Carcinoma C1306837
Definition (1)
Also known as chromophil carcinoma, it represents a minority of renal cell carcinomas. It can be hereditary or sporadic. The sporadic papillary renal cell carcinoma is characterized by trisomy of chromosomes 7, 16, and 17, and loss of chromosome Y. The peak incidence is in the sixth and seven decades. It is classified as type 1 or 2, based on the cytoplasmic volume and the thickness of the lining neoplastic cells. The prognosis is more favorable than for conventional (clear cell) renal cell carcinoma. -- 2003
Relationships (34)

Relation Types:
diso_​to_​anat : 18
diso_​to_​diso : 16


Relationships:
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 4
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 4
may_​be_​cytogenetic_​abnormality_​of_​disease : 1
may_​be_​finding_​of_​disease : 5
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Adenocarcinoma Cell C1510779
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Kidney C0022646
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Kidney Tubules C0022674
DISO_to_ANATis_associated_anatomic_site_ofimg Kidney and Ureter C1881331
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Renal Tubular Epithelial Cell C1266872
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Renal Tubule Epithelium C1709902
DISO_to_ANATis_associated_anatomic_site_ofimg Urinary system C1508753
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOmay_be_finding_of_diseaseimg Cystic Change C1511605
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOmay_be_finding_of_diseaseimg Flank Pain C0016199
DISO_to_DISOmay_be_finding_of_diseaseimg Hematuria C0018965
DISO_to_DISOisaimg Hereditary Papillary Renal Carcinoma C0879257
DISO_to_DISOis_not_finding_of_diseaseimg Mixed Neoplastic Glandular and Squamous Cell Population C1881876
Genes (21)

Species:
human : 20
mouse : 1
SpeciesGeneGeneIdGene NameEvidence
MousePRCC5546papillary renal cell carcinoma (translocation-associated)
img NCI, Score=801, Pubmed Id: 11263992, UMLKSK CUI: C1306837
HumanCDC7379577cell division cycle 73
img OMIM, Score=1000, UMLKSK CUI: C1306837
HumanASPSCR179058alveolar soft part sarcoma chromosome region, candidate 1
img NCI, Score=801, Pubmed Id: 11358836, UMLKSK CUI: C1306837
HumanAMACR23600alpha-methylacyl-CoA racemase
img NCI, Score=801, Pubmed Id: 14707866, UMLKSK CUI: C1306837
img GENERIF, Score=937, Pubmed Id: 16424894, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 14707866, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 14707866, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 14707866, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 14707866, UMLKSK CUI: C1306837
HumanMAD2L210459MAD2 mitotic arrest deficient-like 2 (yeast)
img NCI, Score=801, Pubmed Id: 15218244, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 15218244, UMLKSK CUI: C1306837
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
img GAD, Score=918, Pubmed Id: 8758207, UMLKSK CUI: C1306837
HumanTFE37030transcription factor binding to IGHM enhancer 3
img NCI, Score=801, Pubmed Id: 11313942, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 8986805, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11717438, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 9393982, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11358836, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 12902986, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11313942, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 12902986, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11244503, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 9393982, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11313942, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 8872474, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 12902986, UMLKSK CUI: C1306837
HumanSFPQ6421splicing factor proline/glutamine-rich
img NCI, Score=801, Pubmed Id: 9393982, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 9393982, UMLKSK CUI: C1306837
img GENERIF, Score=991, Pubmed Id: 16832349, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11313942, UMLKSK CUI: C1306837
HumanPXN5829paxillin
img GENERIF, Score=991, Pubmed Id: 11759057, UMLKSK CUI: C1306837
HumanPRCC5546papillary renal cell carcinoma (translocation-associated)
img NCI, Score=801, Pubmed Id: 11313942, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 15218244, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10644981, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 8986805, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11313942, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 15218244, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11717438, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10644981, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 8872474, UMLKSK CUI: C1306837
HumanPAX25076paired box 2
img NCI, Score=801, Pubmed Id: 15502805, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 15502805, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 15502805, UMLKSK CUI: C1306837
HumanNONO4841non-POU domain containing, octamer-binding
img NCI, Score=801, Pubmed Id: 9393982, UMLKSK CUI: C1306837
HumanMST14485macrophage stimulating 1 (hepatocyte growth factor-like)
img NCI, Score=801, Pubmed Id: 7906993, UMLKSK CUI: C1306837
HumanMET4233met proto-oncogene
img NCI, Score=801, Pubmed Id: 9140397, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10327054, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11197838, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10871851, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 11354004, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 9140397, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10327054, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 12147692, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 9140397, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10874308, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10327054, UMLKSK CUI: C1306837
img GENERIF, Score=1000, Pubmed Id: 15579033, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10327054, UMLKSK CUI: C1306837
img GENERIF, Score=771, Pubmed Id: 18636147, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 10698493, UMLKSK CUI: C1306837
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
img GENERIF, Score=991, Pubmed Id: 15073597, UMLKSK CUI: C1306837
HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
img NCI, Score=801, Pubmed Id: 9923855, UMLKSK CUI: C1306837
HumanFGF72252fibroblast growth factor 7
img NCI, Score=801, Pubmed Id: 9094999, UMLKSK CUI: C1306837
HumanCDH161014cadherin 16, KSP-cadherin
img NCI, Score=801, Pubmed Id: 15712178, UMLKSK CUI: C1306837
img NCI, Score=801, Pubmed Id: 15712178, UMLKSK CUI: C1306837
HumanCD3E916CD3e molecule, epsilon (CD3-TCR complex)
img GENERIF, Score=1000, Pubmed Id: 16308105, UMLKSK CUI: C1306837
HumanBSG682basigin (Ok blood group)
img GENERIF, Score=1000, Pubmed Id: 16771728, UMLKSK CUI: C1306837
HumanBRAF673v-raf murine sarcoma viral oncogene homolog B
img NCI, Score=801, Pubmed Id: 12918080, UMLKSK CUI: C1306837
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1306837Papillary Renal Cell Carcinoma0self