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Details
Link-It Detail - Disease - Agranular CD4+ CD56+ Hematodermic Neoplasm/Tumor
Debug Stats
  • ### Total Build Time: 8 ms 16.526 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 442 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 9.686 KB
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 4.772 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.182 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Agranular CD4+ CD56+ Hematodermic Neoplasm/Tumor C1301363
Definition (1)
An aggressive immature hematologic neoplasm formerly known as blastic NK cell lymphoma, composed of cells with a lymphoblast-like morphology. Recent evidence suggests derivation from a plasmacytoid dendritic cell precursor. Patients present with cutaneous tumors and disseminated disease.
Relationships (19)

Relation Types:
diso_​to_​anat : 10
diso_​to_​diso : 9


Relationships:
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 4
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
may_​be_​finding_​of_​disease : 3
replaces : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg CD4+/CD56+ Neoplastic Medium-Sized Cell C1514017
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_associated_anatomic_site_ofimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_associated_anatomic_site_ofimg Integumentary System C0037267
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Plasmacytoid Dendritic Cell Precursor C1709563
DISO_to_ANATis_associated_anatomic_site_ofimg Skin C1123023
DISO_to_DISOmay_be_finding_of_diseaseimg Aggressive Clinical Course C1332223
DISO_to_DISOreplacesimg Agranular CD4+ CD56+ Hematodermic Neoplasm/Tumor C1301363
DISO_to_DISOis_finding_of_diseaseimg CD4-Positive Neoplastic Cells Present C1707102
DISO_to_DISOis_finding_of_diseaseimg CD56-Positive Neoplastic Cells Present C1707104
DISO_to_DISOis_finding_of_diseaseimg Cutaneous Involvement C1511567
DISO_to_DISOis_finding_of_diseaseimg Cutaneous Nodule C0037287
DISO_to_DISOmay_be_finding_of_diseaseimg Extensive Disease C0849867
DISO_to_DISOis_not_finding_of_diseaseimg Favorable Clinical Outcome C1333602
DISO_to_DISOmay_be_finding_of_diseaseimg Lymphadenopathy C0497156
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanKLRD13824killer cell lectin-like receptor subfamily D, member 1
img NCI, Score=801, Pubmed Id: 11722437, UMLKSK CUI: C1301363
HumanKLRB13820killer cell lectin-like receptor subfamily B, member 1
img NCI, Score=801, Pubmed Id: 11722437, UMLKSK CUI: C1301363
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
img NCI, Score=801, Pubmed Id: 11676855, UMLKSK CUI: C1301363
HumanCD33945CD33 molecule
img NCI, Score=801, Pubmed Id: 11328295, UMLKSK CUI: C1301363
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1301363Agranular CD4+ CD56+ Hematodermic Neoplasm/Tumor0self