Human | CCR2 | 729230 | chemokine (C-C motif) receptor 2 | infiltrated neutrophils from patients with chronic inflammatory lung diseases and rheumatoid arthritis highly express CCR1, CCR2, CCR3, CCR5, CXCR3, and CXCR4 |
Human | S100A7A | 338324 | S100 calcium binding protein A7A | Overexpression of hS100A15 in chronic inflammatory skin diseases and regulation by inflammatory cytokines and calcium suggest that hS100A15 is involved in Th1-associated epithelial responses and epidermal maturation in normal and diseased human skin |
Human | NOD2 | 64127 | nucleotide-binding oligomerization domain containing 2 | genetic variations in the NOD2 gene may have roles in the pathophysiology of chronic inflammatory bowel disease |
Human | ITLN1 | 55600 | intelectin 1 (galactofuranose binding) | Val109Asp sequence variation is more a single nucleotide polymorphism than a real disease-causing mutation in type 2 diabetes or chronic inflammatory bowel disease |
Human | AOC3 | 8639 | amine oxidase, copper containing 3 | This study indicates the important role of VAP-1 in the pathogenesis of chronic inflammatory cutaneous disorders, including AE |
Human | CXCR4 | 7852 | chemokine (C-X-C motif) receptor 4 | infiltrated neutrophils from patients with chronic inflammatory lung diseases and rheumatoid arthritis highly express CCR1, CCR2, CCR3, CCR5, CXCR3, and CXCR4 |
Human | TNFRSF1B | 7133 | tumor necrosis factor receptor superfamily, member 1B | Review: role in signaling in chronic inflammatory disorders |
Human | TNFRSF1A | 7132 | tumor necrosis factor receptor superfamily, member 1A | Two amino acid substitutions may be associated with chronic inflammatory disorders, such as SLE, or not |
Human | TNF | 7124 | tumor necrosis factor | TNF is the master regulator of other inflammatory cytokines in the synovial membrane and the major cytokine in the pathogenesis of chronic inflammatory disease [review] |
Human | SFTPC | 6440 | surfactant protein C | Concentration or molecular form of SP-B and SP-C is not altered in bronchoalveolar lavage fluid of children with different acute and chronic inflammatory lung diseases |
Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Cyclooxygenase-2 functional promoter variants may influence susceptibility to acute and chronic inflammatory diseases COX-2 may be involved in inflammatory responses in chronic pancreatitis and in the progression of this chronic inflammatory disease |
Human | PLP1 | 5354 | proteolipid protein 1 | Transgenic mice overexpressing proteolipid protein develop a low-grade chronic inflammatory disease of the central nervous system white matter tracts with an increase in both CD8-positive T-lymphocytes and CD11b-positive macrophage-like cells |
Human | CXCR3 | 2833 | chemokine (C-X-C motif) receptor 3 | infiltrated neutrophils from patients with chronic inflammatory lung diseases and rheumatoid arthritis highly express CCR1, CCR2, CCR3, CCR5, CXCR3, and CXCR4 |
Human | SLC37A4 | 2542 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | Chronic inflammatory bowel disease (IBD) |
Human | CCR5 | 1234 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | infiltrated neutrophils from patients with chronic inflammatory lung diseases and rheumatoid arthritis highly express CCR1, CCR2, CCR3, CCR5, CXCR3, and CXCR4 |
Human | CCR3 | 1232 | chemokine (C-C motif) receptor 3 | infiltrated neutrophils from patients with chronic inflammatory lung diseases and rheumatoid arthritis highly express CCR1, CCR2, CCR3, CCR5, CXCR3, and CXCR4 |
Human | CCR1 | 1230 | chemokine (C-C motif) receptor 1 | infiltrated neutrophils from patients with chronic inflammatory lung diseases and rheumatoid arthritis highly express CCR1, CCR2, CCR3, CCR5, CXCR3, and CXCR4 |
Human | CD40LG | 959 | CD40 ligand | REVIEW: CD40-CD154 interaction can upregulate costimulatory molecules, activate antigen-presenting cells, influence T-cell priming and T-cell-mediated effector functions as well as participate in the pathogenic processing of chronic inflammatory diseases |
Human | CD40 | 958 | CD40 molecule, TNF receptor superfamily member 5 | REVIEW: CD40-CD154 interaction can upregulate costimulatory molecules, activate antigen-presenting cells, influence T-cell priming and T-cell-mediated effector functions as well as participate in the pathogenic processing of chronic inflammatory diseases |
Human | TNFSF8 | 944 | tumor necrosis factor (ligand) superfamily, member 8 | Mast cells were found to be the predominant CD30 ligand-positive (CD30L-positive) cell in the chronic inflammatory skin diseases psoriasis and atopic dermatitis |