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Details
Link-It Detail - Disease - Dendritic Cell Sarcoma, Follicular
Debug Stats
  • ### Total Build Time: 29 ms 25.347 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 366 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 759 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 568 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 2.808 KB
  • CONCEPT_RELATIONSHIPS gt=9 ms Completed: 9 ms rowSize= 14.702 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 4.798 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dendritic Cell Sarcoma, Follicular C1260325
Definition (1)
A neoplasm composed of spindle to ovoid cells which have morphologic and immunophenotypic characteristics of follicular dendritic cells. It affects lymph nodes and other sites including the tonsils, gastrointestinal tract, spleen, liver, soft tissues, skin, and oral cavity. It usually behaves as a low grade sarcoma. Treatment options include complete surgical removal of the tumor with or without adjuvant chemotherapy or radiotherapy. Recurrences have been reported in up to half of the cases. Cases which present with abdominal involvement and a high morphologic grade usually have a poorer prognosis.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Histiocytic Disorders, Malignant C0019613
Ancestral Roots
RootRoot Plus OneDepthParent
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242285img Histiocytic Disorders, Malignant C0019613
img Neoplasms C0027651img Neoplasms by Histologic Type C00276524img Histiocytic Disorders, Malignant C0019613
Relationships (31)

Relation Types:
diso_​to_​anat : 12
diso_​to_​diso : 18
diso_​to_​phen : 1


Relationships:
none : 5
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 4
is_​not_​molecular_​abnormality_​of_​disease : 2
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​finding_​of_​disease : 7
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO13img Complication Aspects C1171258
DISO_to_DISO11img Head and Neck Neoplasms C0018671
DISO_to_ANAT6img Dendritic Cell, Follicular C0242245
DISO_to_ANAT6img Lymph Nodes C0024204
DISO_to_DISO6img Liver Neoplasms C0023903
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Dendritic Cell, Follicular C0242245
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Germinal Center C0282491
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_associated_anatomic_site_ofimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Histiocytic and Dendritic Cell C1708370
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Follicular Dendritic Cell C1513968
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Histiocytic and Dendritic Cell C1709179
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Angiolymphoid hyperplasia C0017531
DISO_to_DISOmay_be_finding_of_diseaseimg Asymptomatic Mass C1516076
DISO_to_DISOis_not_finding_of_diseaseimg Birbeck Granules Present C1706961
DISO_to_DISOis_not_finding_of_diseaseimg CD1a-Positive Neoplastic Cells Present C1707094
DISO_to_DISOmay_be_finding_of_diseaseimg CD21-Positive Neoplastic Cells Present C1707095
DISO_to_DISOis_not_finding_of_diseaseimg CD30+ Neoplastic Cells Present C1511421
DISO_to_DISOmay_be_finding_of_diseaseimg CD35-Positive Neoplastic Cells Present C1707099
DISO_to_DISOis_not_molecular_abnormality_of_diseaseimg Clonal Immunoglobulin Gene Rearrangement C1516672
DISO_to_DISOis_not_molecular_abnormality_of_diseaseimg Clonal T-Cell Receptor Gene Rearrangement C1516680
DISO_to_DISOis_not_finding_of_diseaseimg HMB-45-Positive Neoplastic Cells Present C1708279
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanPDPN10630podoplanin
img GENERIF, Score=983, Pubmed Id: 17951199, UMLKSK CUI: C1260325
HumanCLDN19076claudin 1
img GENERIF, Score=1000, Pubmed Id: 18227718, UMLKSK CUI: C1260325
HumanSLC2A16513solute carrier family 2 (facilitated glucose transporter), member 1
img GENERIF, Score=1000, Pubmed Id: 18227718, UMLKSK CUI: C1260325
HumanCLU1191clusterin
img GENERIF, Score=1000, Pubmed Id: 15252304, UMLKSK CUI: C1260325
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1260325Dendritic Cell Sarcoma, Follicular0self