Human | TRIO | 7204 | trio Rho guanine nucleotide exchange factor | TRIO amplification is associated with invasive tumor growth and rapid tumor cell proliferation in bladder neoplasms |
Human | SEL1L | 6400 | sel-1 suppressor of lin-12-like (C. elegans) | SEL1L alters the expression of mediators involved in the remodeling of the extracellular matrix by creating a microenvironment that is unfavorable to invasive growth |
Human | NOS2 | 4843 | nitric oxide synthase 2, inducible | A positive correlation was found between the positive expression of iNOS mRNA and invasive growth as well as neck lymph node metastatsis of squamous cell carcinoma of tongue |
Human | MYC | 4609 | v-myc avian myelocytomatosis viral oncogene homolog | conclude that alterations of the CMYC gene, including copy number gains and amplifications, are linked to genetically unstable bladder cancers that are characterized by a high histologic grade and/or invasive growth |
Human | MST1R | 4486 | macrophage stimulating 1 receptor (c-met-related tyrosine kinase) | RON receptor can interact with each of the three members of the class B Plexins and control tumor invasive growth |
Human | MMP2 | 4313 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | endothelial cell-associated cathepsins B and L are not involved in the invasive growth of capillaries from existing blood vessels and the presence of collagen is necessary for MMP2 expression in endothelial cells |
Human | MET | 4233 | met proto-oncogene | HGF and c-MET are potential orchestrators of invasive growth in head and neck squamous cell carcinoma [review] MET receptor can interact with each of the three members of class B Plexins and control tumor invasive growth |
Human | ITGB3 | 3690 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | CEACAM1 and alpha(v)beta(3) integrin are functionally interconnected with respect to the invasive growth of melanomas |
Human | ITGAV | 3685 | integrin, alpha V | CEACAM1 and alpha(v)beta(3) integrin are functionally interconnected with respect to the invasive growth of melanomas |
Human | HGF | 3082 | hepatocyte growth factor (hepapoietin A; scatter factor) | HGF and c-MET are potential orchestrators of invasive growth in head and neck squamous cell carcinoma [review] |
Human | CTSL1 | 1514 | | endothelial cell-associated cathepsins B and L are not involved in the invasive growth of capillaries from existing blood vessels and the presence of collagen is necessary for MMP2 expression in endothelial cells |
Human | CTSB | 1508 | cathepsin B | endothelial cell-associated cathepsins B and L are not involved in the invasive growth of capillaries from existing blood vessels and the presence of collagen is necessary for MMP2 expression in endothelial cells |
Human | CTNNB1 | 1499 | catenin (cadherin-associated protein), beta 1, 88kDa | results suggest that the Wnt/beta-catenin signaling pathway plays dual functions in head and neck squamous cell carcinoma (HNSCC) development: promoting both cell survival and invasive growth of HNSCC cells |
Human | CDH13 | 1012 | cadherin 13 | tumor-specific downregulation of expression and methylation of CDH13 and CDH1, alone or in combination, may be involved in the development and invasive growth of pituitary adenomas |
Human | CCNB1 | 891 | cyclin B1 | cyclin B1 may have a role in esophageal squamous cell carcinoma invasive growth and metastasis |
Human | CEACAM1 | 634 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | CEACAM1 and alpha(v)beta(3) integrin are functionally interconnected with respect to the invasive growth of melanomas |
Human | ALCAM | 214 | activated leukocyte cell adhesion molecule | Data attribute a novel signaling role to ALCAM in regulation of proteolysis and support its previously postulated sensor function in invasive growth |
Human | AKT1 | 207 | v-akt murine thymoma viral oncogene homolog 1 | The Akt isoforms are required for the HGF-stimulated invasive growth of human salivary gland cancer cells |
Human | ACTN4 | 81 | actinin, alpha 4 | Actinin-4 contributes to the invasive growth of pancreatic ductal carcinoma, and ACTN4 is one of the candidate oncogenes in this chromosome locus |