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Details
Link-It Detail - Disease - Carcinoma, Ductal, Breast
Debug Stats
  • ### Total Build Time: 85 ms 65.799 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 348 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 676 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 987 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=13 ms Completed: 13 ms rowSize= 5.304 KB
  • CONCEPT_RELATIONSHIPS gt=35 ms Completed: 35 ms rowSize= 17.407 KB
  • CONCEPT_GENES gt=25 ms Completed: 25 ms rowSize= 39.747 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.159 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Carcinoma, Ductal, Breast C1134719
Definition (1)
The most common type of invasive breast carcinoma, accounting for approximately 70% of breast carcinomas. The gross appearance is usually typical with an irregular stellate outline. Microscopically, randomly arranged epithelial elements are seen. When large sheets of malignant cells are present, necrosis may be seen. With adequate tissue sampling, in situ carcinoma can be demonstrated in association with the infiltrating carcinoma. The in situ component is nearly always ductal but occasionally may be lobular or both.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Breast Neoplasms C1458155
img Carcinoma, Ductal C1176475
Ancestral Roots
RootRoot Plus OneDepthParent
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372745img Breast Neoplasms C1458155
img Neoplasms C0027651img Neoplasms by Site C00276534img Breast Neoplasms C1458155
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Carcinoma, Ductal C1176475
img Neoplasms C0027651img Neoplasms by Histologic Type C00276527img Carcinoma, Ductal C1176475
Relationships (203)

Relation Types:
diso_​to_​anat : 28
diso_​to_​chem : 43
diso_​to_​diso : 113
diso_​to_​gene : 9
diso_​to_​phen : 2
diso_​to_​phys : 8


Relationships:
none : 116
disease_​has_​associated_​disease : 4
gene_​associated_​with_​disease : 4
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​cytogenetic_​abnormality_​of_​disease : 2
is_​not_​finding_​of_​disease : 1
is_​not_​molecular_​abnormality_​of_​disease : 2
isa : 7
mapped_​to : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 24
may_​be_​finding_​of_​disease : 7
may_​be_​molecular_​abnormality_​of_​disease : 13
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 9
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO2705img Breast Neoplasms C1458155
DISO_to_DISO1702img Breast Neoplasms C1458155
DISO_to_DISO533img Carcinoma, Lobular C0206692
DISO_to_PHEN474img genetic aspects C0017399
DISO_to_DISO317img Carcinoma, Intraductal, Noninfiltrating C0007124
DISO_to_PHEN280img genetic aspects C0017399
DISO_to_DISO265img Carcinoma, Lobular C0206692
DISO_to_CHEM259img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO198img Carcinoma in Situ C0007099
DISO_to_DISO161img Carcinoma, Intraductal, Noninfiltrating C0007124
DISO_to_DISO160img Carcinoma in Situ C0007099
DISO_to_CHEM152img Receptor, erbB-2 C0069515
DISO_to_DISO137img LOCAL NEOPL RECURRENCE C0027643
DISO_to_ANAT125img Breast C0006141
DISO_to_ANAT124img Lymph Nodes C0024204
DISO_to_CHEM112img Estrogen Receptors C0034804
DISO_to_CHEM102img BIOCHEM TUMOR MARKERS C0041366
DISO_to_ANAT97img Breast C0006141
DISO_to_DISO97img Complication Aspects C1171258
DISO_to_DISO89img LOCAL NEOPL RECURRENCE C0027643
DISO_to_ANAT85img Lymph Nodes C0024204
DISO_to_DISO77img BREAST NEOPL MALE C0242788
DISO_to_CHEM75img Receptor, erbB-2 C0069515
DISO_to_CHEM75img Receptors, Progesterone C0034833
DISO_to_CHEM72img NEOPL PROTEINS C0027642
Genes (140)

Species:
human : 139
mouse : 1
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseCST61474cystatin E/M
img NCI, Score=801, Pubmed Id: 15466187, UMLKSK CUI: C1134719
HumanMUC5B727897mucin 5B, oligomeric mucus/gel-forming
img NCI, Score=801, Pubmed Id: 8976874, UMLKSK CUI: C1134719
HumanSFTPA1653509surfactant protein A1
img NCI, Score=801, Pubmed Id: 11710690, UMLKSK CUI: C1134719
HumanMUCL1118430mucin-like 1
img NCI, Score=801, Pubmed Id: 12019145, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 15785316, UMLKSK CUI: C1134719
HumanSCGB3A192304secretoglobin, family 3A, member 1
img NCI, Score=801, Pubmed Id: 14614327, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 15041725, UMLKSK CUI: C1134719
HumanITIH580760inter-alpha-trypsin inhibitor heavy chain family, member 5
img GENERIF, Score=1000, Pubmed Id: 14744536, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 14744536, UMLKSK CUI: C1134719
HumanMUC3B57876mucin 3B, cell surface associated
img NCI, Score=801, Pubmed Id: 8976874, UMLKSK CUI: C1134719
HumanC8orf1756988chromosome 8 open reading frame 17
img NCI, Score=801, Pubmed Id: 12665628, UMLKSK CUI: C1134719
HumanWWOX51741WW domain containing oxidoreductase
img GENERIF, Score=913, Pubmed Id: 15998374, UMLKSK CUI: C1134719
HumanANAPC751434anaphase promoting complex subunit 7
img NCI, Score=801, Pubmed Id: 15743504, UMLKSK CUI: C1134719
HumanCLDN1851208claudin 18
img GENERIF, Score=988, Pubmed Id: 18223320, UMLKSK CUI: C1134719
HumanF11R50848F11 receptor
img NCI, Score=801, Pubmed Id: 12817473, UMLKSK CUI: C1134719
HumanLRP1229967low density lipoprotein receptor-related protein 12
img NCI, Score=801, Pubmed Id: 12231539, UMLKSK CUI: C1134719
HumanCTCF10664CCCTC-binding factor (zinc finger protein)
img NCI, Score=801, Pubmed Id: 14503807, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 14503807, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 14503807, UMLKSK CUI: C1134719
HumanNCOA210499nuclear receptor coactivator 2
img NCI, Score=801, Pubmed Id: 10690532, UMLKSK CUI: C1134719
HumanRAD5010111RAD50 homolog (S. cerevisiae)
img NCI, Score=801, Pubmed Id: 14511253, UMLKSK CUI: C1134719
HumanACTR210097ARP2 actin-related protein 2 homolog (yeast)
img NCI, Score=801, Pubmed Id: 17277766, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 17277766, UMLKSK CUI: C1134719
HumanNR1H49971nuclear receptor subfamily 1, group H, member 4
img GENERIF, Score=756, Pubmed Id: 17047076, UMLKSK CUI: C1134719
HumanMRC29902mannose receptor, C type 2
img NCI, Score=801, Pubmed Id: 11920633, UMLKSK CUI: C1134719
HumanNCOR29612nuclear receptor corepressor 2
img NCI, Score=801, Pubmed Id: 10690532, UMLKSK CUI: C1134719
HumanNCOR19611nuclear receptor corepressor 1
img NCI, Score=801, Pubmed Id: 10690532, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 10690532, UMLKSK CUI: C1134719
HumanCXCL149547chemokine (C-X-C motif) ligand 14
img NCI, Score=801, Pubmed Id: 10784614, UMLKSK CUI: C1134719
HumanKLF49314Kruppel-like factor 4 (gut)
img NCI, Score=801, Pubmed Id: 15102675, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 15102675, UMLKSK CUI: C1134719
HumanPTTG19232pituitary tumor-transforming 1
img GENERIF, Score=771, Pubmed Id: 18594525, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 15846392, UMLKSK CUI: C1134719
img NCI, Score=801, Pubmed Id: 11163117, UMLKSK CUI: C1134719
HumanEBAG99166estrogen receptor binding site associated, antigen, 9
img NCI, Score=801, Pubmed Id: 11742495, UMLKSK CUI: C1134719
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1134719Carcinoma, Ductal, Breast0self