Human | SLC27A1 | 376497 | solute carrier family 27 (fatty acid transporter), member 1 | Title:|Association:Not Found|Conclusion:Not Found |
Human | HDLC3 | 353125 | High density lipoprotein cholesterol, low serum, 3 | in metabolic syndrome, apoA-I-poor, small, dense HDL3c exert defective protection of endothelial cells from oxLDL-induced apoptosis |
Human | ACSM2B | 348158 | acyl-CoA synthetase medium-chain family member 2B | results suggest an involvement of the medium-chain acyl-CoA synthetase 2 (MACS2) Leu513Ser polymorphism in the development of the metabolic syndrome in Caucasian population |
Human | APOA5 | 116519 | apolipoprotein A-V | Click here to display 6 evidence detail records. |
Human | QRFPR | 84109 | pyroglutamylated RFamide peptide receptor | QRFP and GPR103A/B may regulate diverse neuroendocrine and behavioral functions and implicate this neuropeptide system in metabolic syndrome |
Human | FTO | 79068 | fat mass and obesity associated | FTO rs9939609 SNP was associated with an increased risk for metabolic syndrome in a multi-ethnic sample |
Human | UBL5 | 59286 | ubiquitin-like 5 | Title:Genetic variation in BEACON influences quantitative variation in metabolic syndrome-related phenotypes.|Association:Y|Conclusion:Multivariate analysis of these correlated phenotypes also yielded a highly significant association (P = 0.0004), suggesting that BEACON may influence phenotypic variation in metabolic syndrome-related traits. |
Human | ACE2 | 59272 | angiotensin I converting enzyme 2 | ACE2 A/G polymorphism is associated with hypertension in patients with metabolic syndrome |
Human | PNPLA2 | 57104 | patatin-like phospholipase domain containing 2 | Polymorphisms indicate potential role of ATGL in pathways involved in components of the metabolic syndrome |
Human | RETN | 56729 | resistin | Click here to display 5 evidence detail records. |
Human | PARL | 55486 | presenilin associated, rhomboid-like | Variation in PSARL sequence and/or expression may be an important new risk factor for type 2 diabetes and other components of the metabolic syndrome the PARL rs3732581 genetic variant may have a role in insulin levels, metabolic syndrome and coronary artery disease |
Human | GHRL | 51738 | ghrelin/obestatin prepropeptide | Click here to display 7 evidence detail records. |
Human | NOX1 | 27035 | NADPH oxidase 1 | A study evaluating the relationship between phagocytic NADPH oxidase activity and oxidative stress and atherosclerosis in metabolic syndrome patients is presented |
Human | ARHGEF12 | 23365 | Rho guanine nucleotide exchange factor (GEF) 12 | There is no evidence in the Caucasian KORA study that variants of the LARG gene confer susceptibility for type 2 diabetes, insulin sensitivity, or the metabolic syndrome |
Human | LPIN1 | 23175 | lipin 1 | Variants of the LPIN1 gene have significant effects in human metabolic traits and implicate lipin in the pathophysiology of the metabolic syndrome |
Human | CAPN10 | 11132 | calpain 10 | Results suggest that a novel 111/121 haplotype combination created by the CAPN10 SNP-43, -19, and -63 increases the susceptibility to the metabolic syndrome in patients with type 2 diabetes Reduced CAPN10 expression may be risk factor for features associated with metabolic syndrome in obese subjects, although variation in gene does not seem to contribute to risk for developing obesity per se |
Human | PPARGC1A | 10891 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | Title:|Association:Not Found|Conclusion:Not Found |
Human | SLC25A13 | 10165 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | Patients presenting with non-alcoholic fatty liver unrelated to obesity and metabolic syndrome might have citrin deficiency, caused by SLC25A13 gene mutations |
Human | NAMPT | 10135 | nicotinamide phosphoribosyltransferase | Plasma visfatin levels are increased in overweight and obese subjects with metabolic syndrome |
Human | NR1H3 | 10062 | nuclear receptor subfamily 1, group H, member 3 | results suggest that NR1H3 plays an important role in the HDL-cholesterol metabolism and in the genetic susceptibility to metabolic syndrome |
Human | CLOCK | 9575 | clock circadian regulator | the Clock gene CGC haplotype may be protective for the development of obesity and support the hypothesis that genetic variation in the Clock gene may play a role in the development of the metabolic syndrome, type 2 diabetes and cardiovascular disease |
Human | LIPG | 9388 | lipase, endothelial | endothelial lipase plays a role in the etiology of the atherogenic plasma lipoprotein profile characteristic of the metabolic syndrome [review] |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | Click here to display 26 evidence detail records. |
Human | IRS2 | 8660 | insulin receptor substrate 2 | contribution of defective Irs2 signaling to metabolic syndrome-associated alterations |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Decreased plasma total antioxidant activity, NO, and VEGF levels in patients with metabolic syndrome may reflect significant endothelial dysfunction |