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Details
Link-It Detail - Disease - Leukoaraiosis
Debug Stats
  • ### Total Build Time: 74 ms 16.056 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 367 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 415 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=20 ms Completed: 20 ms rowSize= 556 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.530 KB
  • CONCEPT_RELATIONSHIPS gt=22 ms Completed: 22 ms rowSize= 5.597 KB
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 6.256 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukoaraiosis C0948163
Leukoaraioses
Definition (1)
Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS.
Semantic Types (1)
Pathologic Function (T046)
Parents (1)
img Pathologic Processes C0030660
Ancestral Roots
RootRoot Plus OneDepthParent
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306603img Pathologic Processes C0030660
Relationships (12)

Relation Types:
diso_​to_​anat : 3
diso_​to_​diso : 7
diso_​to_​phen : 1
diso_​to_​phys : 1


Relationships:
none : 11
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO42img Complication Aspects C1171258
DISO_to_ANAT36img Brain C0006104
DISO_to_DISO26img Cerebrovascular accident C0038454
DISO_to_DISO20img Cognition Disorders C0009241
DISO_to_DISO18img Brain Ischemia C0007786
DISO_to_ANAT13img Myelinated nerve fiber C0027750
DISO_to_DISO13img Complication Aspects C1171258
DISO_to_ANAT12img Brain C0006104
DISO_to_DISO12img Brain Infarction C0751955
DISO_to_PHEN12img genetic aspects C0017399
DISO_to_PHYS11img Cognition C0009240
DISO_to_DISOpermuted_term_ofimg Leukoaraioses C0948163
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GENERIF, Score=861, Pubmed Id: 14963277, UMLKSK CUI: C0948163
HumanMTHFR4524methylenetetrahydrofolate reductase (NAD(P)H)
img GENERIF, Score=1000, Pubmed Id: 14763962, UMLKSK CUI: C0948163
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=694, Pubmed Id: 17024375, UMLKSK CUI: C0948163
HumanMMP34314matrix metallopeptidase 3 (stromelysin 1, progelatinase)
img GENERIF, Score=694, Pubmed Id: 17024375, UMLKSK CUI: C0948163
HumanACE1636angiotensin I converting enzyme
img GAD, Score=1000, Pubmed Id: 11861692, UMLKSK CUI: C0948163
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0948163Leukoaraiosis0self