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Genes (58)
Species: human : 58 | |
Human | TUBB1 | 81027 | tubulin, beta 1 class VI | TUBB1 Q43P polymorphism does not protect against acute coronary syndrome and premature myocardial infarction | Human | P2RY12 | 64805 | purinergic receptor P2Y, G-protein coupled, 12 | No influence of the T744C polymorphism of the P2Y12 receptor gene on clopidogrel response in acute coronary syndrome | Human | ACE2 | 59272 | angiotensin I converting enzyme 2 | Found that the A1075 allele of the ACE2 gene was independently associated with higher mortality in an acute coronary syndrome cohort of males of predominantly European ancestry | Human | CXCL16 | 58191 | chemokine (C-X-C motif) ligand 16 | CXCL16 levels in the acute coronary syndrome group were higher than controls and stable angina pectoris group Increased level of serum-soluble CXCL16 was independently associated with acute coronary syndromes | Human | RETN | 56729 | resistin | Plasma resistin levels are associated with myocardium injury in patients with acute coronary syndrome | Human | PROZ | 8858 | protein Z, vitamin K-dependent plasma glycoprotein | protein Z deficiency could be also a risk factor for acute coronary syndromes, early fetal losses, and increased the arterial risk in antiphospholipid syndrome--REVIEW | Human | VWF | 7450 | von Willebrand factor | A marker of endothelial damage/injury in the activation of vascular and coagulation abnormalities in acute coronary syndromes | Human | VCAM1 | 7412 | vascular cell adhesion molecule 1 | Elevated soluble CD40 ligand is related to the endothelial adhesion molecules in patients with acute coronary syndrome | Human | TNNI3 | 7137 | troponin I type 3 (cardiac) | cTnI elevation after PCI predicts adverse outcome after one year in patients with acute coronary syndromes, but not in patients with stable angine pectoris Persistent cTnI elevation occurs frequently late after acute coronary syndrome | Human | TNNI1 | 7135 | troponin I type 1 (skeletal, slow) | Relationship between myocardial injury, assessed by cardiac troponin I (cTnI) levels, and outcome in selected critically ill patients without acute coronary syndromes or cardiac dysfunction | Human | TNF | 7124 | tumor necrosis factor | TNF-alpha polymorphism is associated with the development of acute coronary syndromes | Human | TLR4 | 7099 | toll-like receptor 4 | The Asp299Gly polymorphism provides evidence of an association of the TLR4 receptor and acute coronary syndromes Title:Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.|Association:Y|Conclusion:These results, which must be confirmed by a prospective longitudinal study, provide evidence of an association between the Asp299Gly polymorphism of the human TLR4 receptor and acute coronary syndromes. They confirm the previously reported involvement of TLR4 in carotid and femoral artery atherosclerosis. | Human | TIMP2 | 7077 | TIMP metallopeptidase inhibitor 2 | MMP-9, but not TIMP-1 nor MMP-2 expression is increased in plaques causing acute coronary syndrome | Human | THBD | 7056 | thrombomodulin | Title:Genetic variation in the human thrombomodulin promoter locus and prognosis after acute coronary syndrome|Association:Not Found|Conclusion:We identified 10 point mutations and 2 small deletions: -1861 C/A, -1852 C/G, -1803 G/C, -1752 G/C, -1213/1212 delTT, -1089 C/G, -1088 C/T, -1083/1082 delCC, -1066 A/C, -801 C/G, -651 A/C and -52 G/A. Two of the mutations, -1752 G/C and -1213/1212 delTT, were frequent in the patients as well as in the controls, while all the others were rare. The only significant finding was that both -1752 G/C and -1213/1212 delTT were associated with a lower than normal risk of suffering a clinical event among smokers at 30 days and 2 years. We did not gain any support for the hypothesis that TM mutations confer an increased risk of MI or mortality. identified 10 point mutations and 2 small deletions in the promoter region in 182 patients with acute coronary syndrome Increasing plasma TM predicts worse clinical outcome in acute coronary syndromes | Human | TGFB1 | 7040 | transforming growth factor, beta 1 | Decreased activity of TGFbeta in patients with acute coronary syndromes is at least partly due altered transcriptional activity of genes encoding TGFbeta | Human | CXCL5 | 6374 | chemokine (C-X-C motif) ligand 5 | CXCL5/ENA-78 has a role in acute coronary syndrome and the statin response | Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Common polymorphisms of cyclooxygenase-2 and prostaglandin E2 receptor and increased risk for acute coronary syndrome in coronary artery disease | Human | PSMB9 | 5698 | proteasome (prosome, macropain) subunit, beta type, 9 | Title:|Association:Not Found|Conclusion:Not Found | Human | PSMB8 | 5696 | proteasome (prosome, macropain) subunit, beta type, 8 | Title:|Association:Not Found|Conclusion:Not Found | Human | PRG2 | 5553 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | Pregnancy-associated plasma protein A is involved in processes preceding vulnerable plaque development in acute coronary syndrome | Human | PPARA | 5465 | peroxisome proliferator-activated receptor alpha | Interaction between PPARA genotype and beta-blocker treatment influences clinical outcomes following acute coronary syndromes | Human | PAPPA | 5069 | pregnancy-associated plasma protein A, pappalysin 1 | Proform eosinophilic major basic protein is involved in processes preceding vulnerable plaque development in acute coronary syndrome PAPP-A and IGF-1 are elevated in patients with acute coronary syndrome | Human | P200 | 5035 | | Title:G20210A prothrombin gene variant and clinical outcome in patients with a first acute coronary syndrome.|Association:Not Found|Conclusion:The present prospective study suggests that heterozygosity for the G20210A prothrombin polymorphism adversely affects prognosis after a first acute coronary syndrome in the subgroup of patients without metabolic risk factors and in those not treated by revascularization procedures. | Human | OLR1 | 4973 | oxidized low density lipoprotein (lectin-like) receptor 1 | Serum LOX-1 appears to be a useful marker for early diagnosis of acute coronary syndromes | Human | NPPC | 4880 | natriuretic peptide C | BNP levels appear to be elevated in coronary disease, especially in acute coronary syndromes, even in the absence of systolic dysfunction |
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