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Details
Link-It Detail - Disease - Primary Graft Dysfunction
Debug Stats
  • ### Total Build Time: 90 ms 18.716 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 404 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 440 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 554 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 2.800 KB
  • CONCEPT_RELATIONSHIPS gt=49 ms Completed: 49 ms rowSize= 9.531 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 3.642 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.159 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Primary Graft Dysfunction C0948031
Dysfunction, Primary Graft
Definition (1)
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
Semantic Types (1)
Pathologic Function (T046)
Parents (1)
img Reperfusion Injury C0035126
Ancestral Roots
RootRoot Plus OneDepthParent
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306605img Reperfusion Injury C0035126
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Reperfusion Injury C0035126
Relationships (23)

Relation Types:
diso_​to_​anat : 5
diso_​to_​chem : 2
diso_​to_​diso : 12
diso_​to_​phen : 1
diso_​to_​phys : 3


Relationships:
none : 22
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT19img In Blood C0005768
DISO_to_DISO14img Damage, Reperfusion C0035126
DISO_to_PHYS13img Graft Survival C0018131
DISO_to_PHYS12img Graft Rejection C0018129
DISO_to_CHEM8img Organ Preservation Solutions C0182061
DISO_to_ANAT7img Liver C0023884
DISO_to_ANAT6img Lung C0024109
DISO_to_DISO6img Bronchiolitis Obliterans C0006272
DISO_to_DISO6img Warm Ischemia C1567664
DISO_to_PHEN5img genetic aspects C0017399
DISO_to_DISO4img COMPL POSTOP C0032787
DISO_to_DISO4img chemically induced C0007994
DISO_to_ANAT3img Bronchoalveolar Lavage Fluid C0006279
DISO_to_ANAT3img Kidney C0022646
DISO_to_CHEM3img Abs - Autoantibodies C0004358
DISO_to_DISO3img Acute kidney injury C2609414
DISO_to_DISO3img Cold Ischemia C1563921
DISO_to_DISO3img Fatty Liver C0015695
DISO_to_DISO3img Idiopathic Pulmonary Fibrosis C1800706
DISO_to_DISO3img Lung Diseases C0024115
DISO_to_DISO3img Lung Diseases, Interstitial C0206062
DISO_to_PHYS3img Biological Markers C0005516
DISO_to_DISOpermuted_term_ofimg Dysfunction, Primary Graft C0948031
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanVWF7450von Willebrand factor
img GENERIF, Score=1000, Pubmed Id: 17908278, UMLKSK CUI: C0948031
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=1000, Pubmed Id: 17889209, UMLKSK CUI: C0948031
HumanICAM13383intercellular adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 17908278, UMLKSK CUI: C0948031
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0948031Primary Graft Dysfunction0self