Human | NRG4 | 145957 | neuregulin 4 | NRG4 overexpression is associated with advanced-stage prostate cancer |
Human | IL17RC | 84818 | interleukin 17 receptor C | We identified the most abundant splices in prostate tissue and established a technique to investigate changes in RNA IL-17RL splicing that occur in advanced cancers. BACKGROUND: Interleukin-17 receptor-like protein (IL-17RL) expressed in prostate tissues changes with advanced cancers due to extensive alternative splicing, which affects the final protein. |
Human | S100A14 | 57402 | S100 calcium binding protein A14 | Genes such as AGR2, S100A14, S100A16, FABP1, and others were found useful for detection of CTCs in peripheral blood of advanced cancer patients. |
Human | DIABLO | 56616 | diablo, IAP-binding mitochondrial protein | decreased levels of Smac/DIABLO may be important in chemoradiation-resistance to apoptosis in advanced colon cancer [review] |
Human | IL17RD | 54756 | interleukin 17 receptor D | Sef is downregulated in advanced prostate cancer and might facilitate an enhanced tumorigenic response to FGFs |
Human | UGT1A1 | 54658 | UDP glucuronosyltransferase 1 family, polypeptide A1 | genetic polymorphisms of UGT1A as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil plus oxaliplatin or irinotecan |
Human | RASSF1 | 11186 | Ras association (RalGDS/AF-6) domain family member 1 | RASSF1A promoter methylation is associated with advanced bladder cancer |
Human | PSIP1 | 11168 | PC4 and SFRS1 interacting protein 1 | The objective of the study was to investigate the dynamic changes of cortisol and soluble TNF-alpha p-55 and p-75 receptors in serum of advanced cancer patients during 24 h. The objective of the study was to investigate the dynamic changes in soluble TNFalpha p-55 and p-75 receptors in serum of advanced cancer patients during 24 hours. |
Human | UBE2C | 11065 | ubiquitin-conjugating enzyme E2C | results showing aberrations in levels of gene expression and locus copy number of ubiquitin-conjugating enzyme E2C gene (UBE2C) suggest that this gene may play an important role in tumor progression leading to advanced colon cancer with liver metastasis |
Human | GDF15 | 9518 | growth differentiation factor 15 | Transgenic mice overexpressing MIC-1 show hypophagia and weight loss; sera from subjects with advanced prostate cancer show a direct correlation between MIC-1 abundance and cancer-associated weight loss, defining MIC-1 as a central regulator of appetite |
Human | ABCG2 | 9429 | ATP-binding cassette, sub-family G (WHITE), member 2 | BCRP may serve as a molecular target for reducing drug resistance to chemotherapy in advanced lung cancer patients |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | Decreased circulating levels of adiponectin is associated with advanced lung cancer |
Human | REPS2 | 9185 | RALBP1 associated Eps domain containing 2 | Decreased REPS2 expression is associated with androgen-independent state of advanced prostate cancer |
Human | MTA1 | 9112 | metastasis associated 1 | MTA1 is up-regulated in advanced ovarian cancer, represses ERbeta, and enhances expression of GRO |
Human | TNFRSF6B | 8771 | tumor necrosis factor receptor superfamily, member 6b, decoy | High DcR3 expression is associated with advanced stage gastric cancer |
Human | XRCC1 | 7515 | X-ray repair complementing defective repair in Chinese hamster cells 1 | genetic polymorphisms of XRCC1 as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil plus oxaliplatin or irinotecan |
Human | WNT5A | 7474 | wingless-type MMTV integration site family, member 5A | WNT5A might be downregulated in advanced cancer with poorer prognosis due to genetic alterations compensating WNT5A signaling. |
Human | VEGFC | 7424 | vascular endothelial growth factor C | regulation of VEGF-C expression by NKX3.1 provides a possible mechanism by which the loss of NKX3.1 protein level leads to lymphangiogenesis in the late stages of advanced prostate cancer |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Plasma VEGF warrants further evaluation as a prognostic marker for treatment outcome in advanced breast cancer patients receiving anti-VEGF therapy The mRNA expression levels of Vascular Endothelial Growth Factor A was greater in tissues of early and advanced colon cancer compared with colon adenoma |
Human | VCAM1 | 7412 | vascular cell adhesion molecule 1 | Circulating levels of soluble intracellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin were measured in 20 advanced cancer patients at different times during recombinant interleukin-2 immunotherapy. |
Human | TYMS | 7298 | thymidylate synthetase | Genetic variation is not useful for predicting toxicity from capecitabine in patients with advanced colorectal cancer genetic polymorphisms of TS as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil plus oxaliplatin or irinotecan |
Human | TP53 | 7157 | tumor protein p53 | Current study showed p53 was associated with induction of apoptosis and cell proliferation in early stage gastric cancers, but not in the subserosa of advanced gastric cancer Results suggested that the loss of p53 expression in conjunction with the overexpression of p21(WAF1/CIP1) was a stronger predictor of survival benefit than either molecule alone in Japanese serous-type advanced ovarian cancer The Pro/Pro genotype of the p53 codon 72 polymorphism carries a higher risk for gastric cancer in general and is also associated with a much higher risk for early gastric cancer than advanced gastric cancer There is a molecular association of the p53 codon 72 arginine allele with tumor aggressiveness and treatment resistance in advanced breast cancer |
Human | TNFRSF1B | 7133 | tumor necrosis factor receptor superfamily, member 1B | The objective of the study was to investigate the dynamic changes of cortisol and soluble TNF-alpha p-55 and p-75 receptors in serum of advanced cancer patients during 24 h. The objective of the study was to investigate the dynamic changes in soluble TNFalpha p-55 and p-75 receptors in serum of advanced cancer patients during 24 hours. |
Human | TNF | 7124 | tumor necrosis factor | study shows that PBMCs of patients with advanced gastric cancer show poor production of TNF and IL-12p40 in response to stimulation with tumor cells in vitro & this unresponsiveness is associated in some patients with diminished IRAK-1 expression in vivo |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | TGFB1 polymorphism may play a role in advanced stage prostate cancer Transforming growth factor beta overexpression is associated with advanced stage gallbladder cancer |