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Details
Link-It Detail - Disease - Bile duct carcinoma
Debug Stats
  • ### Total Build Time: 19 ms 44.422 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.020 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=3 ms Completed: 3 ms rowSize= 11.462 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 30.389 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Bile duct carcinoma C0740277
Definition (1)

Your liver makes a substance called bile that helps with digestion. Your gallbladder stores it until you need it to digest fat. Then your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine.

Bile duct cancer is rare. It can happen in the part of the bile duct that is outside or inside the liver. Cancer of the bile duct outside of the liver is much more common. Risk factors include inflammation of the bile duct, older age, some liver diseases, and exposure to certain chemicals.

Symptoms can include

  • Jaundice
  • Itchy skin
  • Fever
  • Abdominal pain
  • Weight loss

Treatments include surgery, radiation therapy, and chemotherapy.

Relationships (22)

Relation Types:
diso_​to_​anat : 14
diso_​to_​diso : 8


Relationships:
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 2
location_​of : 1
permuted_​term_​of : 1
related_​to : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Bile Duct Epithelium C1711208
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Bile Ducts C0005400
DISO_to_ANATlocation_ofimg Bile Ducts, Intrahepatic C0005401
DISO_to_ANATis_associated_anatomic_site_ofimg Biliary Tract C0005423
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Hepatobiliary System C1711359
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_DISOis_not_finding_of_diseaseimg Benign Cellular Infiltrate C1332480
DISO_to_DISOrelated_toimg Bile Duct Diseases C0005395
DISO_to_DISOisaimg Bile duct adenocarcinoma C1370800
DISO_to_DISOpermuted_term_ofimg Bile duct carcinoma C0740277
DISO_to_DISOisaimg Carcinoma of extrahepatic bile duct C0238019
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOrelated_toimg Malignant neoplasm of gallbladder C0153452
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanMAGED4B81557melanoma antigen family D, 4B
img NCI, Score=801, Pubmed Id: 10873083, UMLKSK CUI: C0740277
HumanACTR210097ARP2 actin-related protein 2 homolog (yeast)
img NCI, Score=801, Pubmed Id: 17277766, UMLKSK CUI: C0740277
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 8611434, UMLKSK CUI: C0740277
HumanSCTR6344secretin receptor
img GENERIF, Score=1000, Pubmed Id: 17678920, UMLKSK CUI: C0740277
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=756, Pubmed Id: 16361272, UMLKSK CUI: C0740277
HumanENPP35169ectonucleotide pyrophosphatase/phosphodiesterase 3
img GENERIF, Score=923, Pubmed Id: 15072822, UMLKSK CUI: C0740277
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 7892048, UMLKSK CUI: C0740277
HumanMGAT54249mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
img NCI, Score=801, Pubmed Id: 8900148, UMLKSK CUI: C0740277
img NCI, Score=801, Pubmed Id: 8900148, UMLKSK CUI: C0740277
HumanSCGB2A14246secretoglobin, family 2A, member 1
img NCI, Score=801, Pubmed Id: 10873083, UMLKSK CUI: C0740277
HumanMDK4192midkine (neurite growth-promoting factor 2)
img NCI, Score=801, Pubmed Id: 7559083, UMLKSK CUI: C0740277
HumanMAGEA14100melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
img NCI, Score=801, Pubmed Id: 10873083, UMLKSK CUI: C0740277
HumanLIMS13987LIM and senescent cell antigen-like domains 1
img NCI, Score=801, Pubmed Id: 12216108, UMLKSK CUI: C0740277
HumanLDLR3949low density lipoprotein receptor
img GENERIF, Score=1000, Pubmed Id: 18296645, UMLKSK CUI: C0740277
HumanHOXB73217homeobox B7
img NCI, Score=801, Pubmed Id: 16673309, UMLKSK CUI: C0740277
img GENERIF, Score=1000, Pubmed Id: 16673309, UMLKSK CUI: C0740277
HumanFOXA13169forkhead box A1
img NCI, Score=801, Pubmed Id: 17163418, UMLKSK CUI: C0740277
HumanGFRA12674GDNF family receptor alpha 1
img NCI, Score=801, Pubmed Id: 11815973, UMLKSK CUI: C0740277
HumanGALNT32591UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
img GENERIF, Score=851, Pubmed Id: 17361208, UMLKSK CUI: C0740277
HumanFIGF2277c-fos induced growth factor (vascular endothelial growth factor D)
img NCI, Score=801, Pubmed Id: 16080559, UMLKSK CUI: C0740277
HumanETS12113v-ets avian erythroblastosis virus E26 oncogene homolog 1
img NCI, Score=801, Pubmed Id: 8900148, UMLKSK CUI: C0740277
HumanEGFR1956epidermal growth factor receptor
img GENERIF, Score=1000, Pubmed Id: 16551849, UMLKSK CUI: C0740277
HumanDLAT1737dihydrolipoamide S-acetyltransferase
img NCI, Score=801, Pubmed Id: 12108679, UMLKSK CUI: C0740277
HumanASPH444aspartate beta-hydroxylase
img GENERIF, Score=1000, Pubmed Id: 16673309, UMLKSK CUI: C0740277
HumanFASLG356Fas ligand (TNF superfamily, member 6)
img GENERIF, Score=1000, Pubmed Id: 15138553, UMLKSK CUI: C0740277
HumanFAS355Fas cell surface death receptor
img GENERIF, Score=1000, Pubmed Id: 15138553, UMLKSK CUI: C0740277
HumanAPOE348apolipoprotein E
img GENERIF, Score=1000, Pubmed Id: 18296645, UMLKSK CUI: C0740277
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0740277Bile duct carcinoma0self