Human | CCM2 | 83605 | cerebral cavernous malformation 2 | |
Human | RAMP1 | 10267 | receptor (G protein-coupled) activity modifying protein 1 | We did not observe any difference in mRNA for CL-R and RAMPs in arteries from patients with hemorrhagic stroke, arteriosclerosis and acute myocardial infarction when compared to patients without these diagnoses |
Human | VWF | 7450 | von Willebrand factor | Greater plasma fibrinogen and, to some degree, von Willebrand factor were associated with increased rates of hemorrhagic stroke in these prospective studies, whereas Factor VIII was related to it in younger ARIC study participants only |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Title:Absence of alpha-1 antitrypsin deficiency alleles (S and Z) in Japanese and Korean patients with aneurysmal subarachnoid hemorrhage.|Association:Not Found|Conclusion:AAT deficiency may not be a common genetic risk factor for aneurysmal subarachnoid hemorrhage in Japanese and Koreans. |
Human | NOS3 | 4846 | nitric oxide synthase 3 (endothelial cell) | Title:Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage and cerebral vasospasm.|Association:Not Found|Conclusion:We believe that genetic information such as this, which can be obtained expeditiously at the time of diagnosis, may be used as a helpful adjunct to other clinical information aimed at predicting and favorably modifying the clinical course of persons with intracranial aneurysms. |
Human | MMP9 | 4318 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | Higher levels of MMP-9 in human brain tissue after ischemic and hemorrhagic stroke, suggesting a contribution of MMP-9 to ischemic brain injury and perihematoma edema |
Human | ITGB3 | 3690 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | Title:Polymorphisms of platelet adhesive receptors: dothey play a role in primary intracerebral hemorrhage?|Association:Not Found|Conclusion:Our results suggest that these polymorphisms play a minor role in PIH. |
Human | ITGA2 | 3673 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | Title:Polymorphisms of platelet adhesive receptors: dothey play a role in primary intracerebral hemorrhage?|Association:Not Found|Conclusion:Our results suggest that these polymorphisms play a minor role in PIH. |
Human | HFE | 3077 | hemochromatosis | HFE genotypes did not influence the risk of ischemic or hemorrhagic stroke |
Human | GP1BA | 2811 | glycoprotein Ib (platelet), alpha polypeptide | Title:Polymorphisms of platelet adhesive receptors: dothey play a role in primary intracerebral hemorrhage?|Association:Not Found|Conclusion:Our results suggest that these polymorphisms play a minor role in PIH. |
Human | F13A1 | 2162 | coagulation factor XIII, A1 polypeptide | Polymorphisms of coagulation factor XIII subunit A and risk of hemorrhagic stroke in young white women |
Human | F8 | 2157 | coagulation factor VIII, procoagulant component | Greater plasma fibrinogen and, to some degree, von Willebrand factor were associated with increased rates of hemorrhagic stroke in these prospective studies, whereas Factor VIII was related to it in younger ARIC study participants only |
Human | F2R | 2149 | coagulation factor II (thrombin) receptor | Hypothesis that statins increase risk of hemorrhagic stroke by inhibiting PAR1 receptor is plausible but requires further direct testing in randomized trials |
Human | APOH | 350 | apolipoprotein H (beta-2-glycoprotein I) | Title:Apolipoprotein H genetic variability in the population of Krk Island, Croatia|Association:Not Found|Conclusion:No significant differences between villages were observed. When these data were compared to those of other populations studied so far, a significant association between APOH allele frequencies and latitude was observed. We hypothesize that this association reflects differences in diet composition across different climatic zones. Title:Apolipoprotein H gene polymorphisms and risk of primary cerebral hemorrhage in a Chinese population.|Association:Not Found|Conclusion:Our results suggest that the G341A (Ser88Asn) polymorphism might be associated with increased risk of PICH in a Chinese population. The association appeared to be mediated by the generation of hypertension. |
Human | ADD1 | 118 | adducin 1 (alpha) | Title:[Alpha-adducin gene G/W460 polymorphism is associated with intracerebral hemorrhage in Chinese]|Association:Y|Conclusion:Alpha-adducin gene G/W 460 polymorphism is significantly associated with the risk of ICH. This association does not appear to be mediated by established ICH risk factors, specifically hypertension status. |
Human | SERPINA3 | 12 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | alpha(1)-antichymotrypsin polymorphism: a risk factor for hemorrhagic stroke in normotensive subjects |