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Details
Link-It Detail - Disease - Atopy
Debug Stats
  • ### Total Build Time: 30 ms 37.082 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 308 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 431 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=3 ms Completed: 3 ms rowSize= 2.962 KB
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 32.188 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.140 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Atopy C0392707
Definition (1)
genetic predisposition toward the development of immediate (type I) hypersensitivity reactions against common environmental antigens (atopic allergy); the most common clinical manifestation is allergic rhinitis; bronchial asthmas, atopic dermatitis and food allergy also occur.
Relationships (5)

Relation Types:
diso_​to_​diso : 1
diso_​to_​gene : 4


Relationships:
gene_​associated_​with_​disease : 4
isa : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISOisaimg Atopic constitution as co-factor C1304048
DISO_to_GENEgene_associated_with_diseaseimg IL4R gene C1334118
DISO_to_GENEgene_associated_with_diseaseimg IL4R wt Allele C1705220
DISO_to_GENEgene_associated_with_diseaseimg SELP gene C1335809
DISO_to_GENEgene_associated_with_diseaseimg SELP wt Allele C1705801
Genes (72)

Species:
human : 72
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanHAVCR284868hepatitis A virus cellular receptor 2
img GENERIF, Score=928, Pubmed Id: 15603868, UMLKSK CUI: C0392707
HumanIL2159067interleukin 21
img GENERIF, Score=983, Pubmed Id: 15919378, UMLKSK CUI: C0392707
HumanCYSLTR257105cysteinyl leukotriene receptor 2
img GAD, Score=1000, Pubmed Id: 14515063, UMLKSK CUI: C0392707
img GENERIF, Score=1000, Pubmed Id: 14515063, UMLKSK CUI: C0392707
HumanTLR954106toll-like receptor 9
img GAD, Score=1000, Pubmed Id: 16164440, UMLKSK CUI: C0392707
HumanFOXP350943forkhead box P3
img OMIM, Score=1000, UMLKSK CUI: C0392707
HumanHAVCR126762hepatitis A virus cellular receptor 1
img GENERIF, Score=944, Pubmed Id: 14534576, UMLKSK CUI: C0392707
img GENERIF, Score=928, Pubmed Id: 15007635, UMLKSK CUI: C0392707
HumanSPINK511005serine peptidase inhibitor, Kazal type 5
img GAD, Score=790, Pubmed Id: 11544479, UMLKSK CUI: C0392707
HumanNOD110392nucleotide-binding oligomerization domain containing 1
img GENERIF, Score=694, Pubmed Id: 15990792, UMLKSK CUI: C0392707
HumanIL1RL19173interleukin 1 receptor-like 1
img GENERIF, Score=1000, Pubmed Id: 18774397, UMLKSK CUI: C0392707
HumanSART19092squamous cell carcinoma antigen recognized by T cells
img GENERIF, Score=1000, Pubmed Id: 12189166, UMLKSK CUI: C0392707
HumanIL18R18809interleukin 18 receptor 1
img GENERIF, Score=1000, Pubmed Id: 18774397, UMLKSK CUI: C0392707
HumanIL18RAP8807interleukin 18 receptor accessory protein
img GENERIF, Score=1000, Pubmed Id: 18774397, UMLKSK CUI: C0392707
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img GENERIF, Score=1000, Pubmed Id: 15282199, UMLKSK CUI: C0392707
HumanSCGB1A17356secretoglobin, family 1A, member 1 (uteroglobin)
img GENERIF, Score=827, Pubmed Id: 17716718, UMLKSK CUI: C0392707
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 18385169, UMLKSK CUI: C0392707
HumanTLR47099toll-like receptor 4
img GENERIF, Score=660, Pubmed Id: 12406828, UMLKSK CUI: C0392707
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=928, Pubmed Id: 15373772, UMLKSK CUI: C0392707
img GENERIF, Score=694, Pubmed Id: 17333284, UMLKSK CUI: C0392707
HumanTAP16890transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
img GAD, Score=1000, Pubmed Id: 9042048, UMLKSK CUI: C0392707
HumanSTAT66778signal transducer and activator of transcription 6, interleukin-4 induced
img GENERIF, Score=928, Pubmed Id: 15342695, UMLKSK CUI: C0392707
img GENERIF, Score=1000, Pubmed Id: 15105161, UMLKSK CUI: C0392707
HumanSLC11A16556solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
img GAD, Score=1000, Pubmed Id: 11960304, UMLKSK CUI: C0392707
HumanSFTPD6441surfactant protein D
img GENERIF, Score=1000, Pubmed Id: 18355911, UMLKSK CUI: C0392707
HumanSELP6403selectin P (granule membrane protein 140kDa, antigen CD62)
img GAD, Score=666, Pubmed Id: 12929084, UMLKSK CUI: C0392707
HumanCCL116356chemokine (C-C motif) ligand 11
img GAD, Score=1000, Pubmed Id: 9120022, UMLKSK CUI: C0392707
HumanRNASE36037ribonuclease, RNase A family, 3
img GENERIF, Score=861, Pubmed Id: 14630983, UMLKSK CUI: C0392707
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 17573729, UMLKSK CUI: C0392707
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0392707Atopy0self