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Details
Link-It Detail - Disease - Cervical intraepithelial neoplasia grade 1
Debug Stats
  • ### Total Build Time: 55 ms 22.620 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 382 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 597 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=33 ms Completed: 33 ms rowSize= 9.891 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 10.527 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.176 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cervical intraepithelial neoplasia grade 1 C0349458
Definition (1)
A precancerous neoplastic process that affects the cervical epithelium without evidence of invasion. It is usually associated with human papillomavirus infection. It is characterized by the presence of mild atypia in the superficial epithelial layer that may be associated with koilocytosis. Maturation is present in the upper two thirds of the epithelium. Mitotic figures are not numerous and are present in the basal third of the epithelium.
Relationships (18)

Relation Types:
diso_​to_​anat : 10
diso_​to_​diso : 8


Relationships:
classifies : 1
expanded_​form_​of : 1
is_​abnormal_​cell_​of_​disease : 2
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Cervix Epithelium C1711358
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Cervix Uteri C0007874
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Uterus C0042149
DISO_to_DISOis_finding_of_diseaseimg 74 DYSPLASIAS C0334044
DISO_to_DISOexpanded_form_ofimg Cervical intraepithelial neoplasia grade 1 C0349458
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOis_not_finding_of_diseaseimg Invasive Lesion C1334278
DISO_to_DISOisaimg Low Grade Cervical Glandular Intraepithelial Neoplasia C1334420
DISO_to_DISOisaimg Low Grade Cervical Squamous Intraepithelial Neoplasia C1518005
DISO_to_DISOis_finding_of_diseaseimg Mild dysplasia C0334046
DISO_to_DISOclassifiesimg Other and unspecified female genital disorders C0497480
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanVCAM17412vascular cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 7518736, UMLKSK CUI: C0349458
HumanRBL25934retinoblastoma-like 2 (p130)
img NCI, Score=801, Pubmed Id: 16158962, UMLKSK CUI: C0349458
HumanJUN3725jun proto-oncogene
img NCI, Score=801, Pubmed Id: 9018063, UMLKSK CUI: C0349458
HumanDNAJB13337DnaJ (Hsp40) homolog, subfamily B, member 1
img NCI, Score=801, Pubmed Id: 16112431, UMLKSK CUI: C0349458
HumanFLT42324fms-related tyrosine kinase 4
img NCI, Score=801, Pubmed Id: 14648657, UMLKSK CUI: C0349458
img NCI, Score=801, Pubmed Id: 14648657, UMLKSK CUI: C0349458
HumanFIGF2277c-fos induced growth factor (vascular endothelial growth factor D)
img NCI, Score=801, Pubmed Id: 14648657, UMLKSK CUI: C0349458
img NCI, Score=801, Pubmed Id: 14648657, UMLKSK CUI: C0349458
HumanCLDN31365claudin 3
img NCI, Score=801, Pubmed Id: 15754293, UMLKSK CUI: C0349458
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0349458Cervical intraepithelial neoplasia grade 10self