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Details
Link-It Detail - Disease - Carcinoma ex Pleomorphic Adenoma
Debug Stats
  • ### Total Build Time: 76 ms 24.002 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 362 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 706 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=47 ms Completed: 47 ms rowSize= 11.493 KB
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 10.229 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Carcinoma ex Pleomorphic Adenoma C0344460
Definition (1)
A carcinoma arising in a pre-existing pleomorphic adenoma. It most often occurs in the parotid gland and less often in the submandibular gland and minor salivary gland. Patients usually present with a history of a long-standing mass which recently had undergone rapid growth. The prognosis depends on the invasiveness of the malignant component. Patients with non-invasive or minimally invasive tumors usually have a good prognosis following surgical resection. Invasive tumors are usually aggressive and are associated with recurrences and metastases.
Relationships (24)

Relation Types:
diso_​to_​anat : 13
diso_​to_​diso : 11


Relationships:
is_​abnormal_​cell_​of_​disease : 4
is_​finding_​of_​disease : 5
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 1
isa : 2
may_​be_​finding_​of_​disease : 4
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Body tissue C0040300
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cells C0007634
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Myoepithelial cell C0225356
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Glial Cell C1513978
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Neuroglia C0027836
DISO_to_DISOisaimg Carcinoma ex Pleomorphic Adenoma of Lacrimal Gland C0346342
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOmay_be_finding_of_diseaseimg Cartilaginous Component Present C1707308
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOmay_be_finding_of_diseaseimg Lipomatous Component Present C1708710
DISO_to_DISOis_finding_of_diseaseimg Mesenchymal Component Present C1708981
DISO_to_DISOis_finding_of_diseaseimg Mixed Cellular Population C1513363
DISO_to_DISOmay_be_finding_of_diseaseimg Myxoid Stroma Formation C1334857
DISO_to_DISOmay_be_finding_of_diseaseimg Osseous Component Present C1709350
DISO_to_DISOisaimg Salivary Gland Carcinoma ex Pleomorphic Adenoma C1519172
DISO_to_DISOis_finding_of_diseaseimg Secondary Lesion C1519215
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanHMGA28091high mobility group AT-hook 2
img GENERIF, Score=1000, Pubmed Id: 18828159, UMLKSK CUI: C0344460
img NCI, Score=801, Pubmed Id: 11839563, UMLKSK CUI: C0344460
img NCI, Score=801, Pubmed Id: 11839563, UMLKSK CUI: C0344460
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 17593217, UMLKSK CUI: C0344460
HumanPLAG15324pleiomorphic adenoma gene 1
img NCI, Score=801, Pubmed Id: 15920557, UMLKSK CUI: C0344460
img NCI, Score=801, Pubmed Id: 15920557, UMLKSK CUI: C0344460
img NCI, Score=801, Pubmed Id: 15920557, UMLKSK CUI: C0344460
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img GENERIF, Score=1000, Pubmed Id: 17927591, UMLKSK CUI: C0344460
HumanCCNA2890cyclin A2
img GENERIF, Score=771, Pubmed Id: 17593077, UMLKSK CUI: C0344460
HumanCCND1595cyclin D1
img GENERIF, Score=1000, Pubmed Id: 17927591, UMLKSK CUI: C0344460
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0344460Carcinoma ex Pleomorphic Adenoma0self