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Details
Link-It Detail - Disease - Eosinophilic esophagitis
Debug Stats
  • ### Total Build Time: 56 ms 16.605 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 346 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 520 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=43 ms Completed: 43 ms rowSize= 11.174 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 3.357 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.158 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Eosinophilic esophagitis C0341106
Definition (1)
Chronic ESOPHAGITIS characterized by esophageal mucosal EOSINOPHILIA. It is diagnosed when an increase in EOSINOPHILS are present over the entire esophagus. The reflux symptoms fail to respond to PROTON PUMP INHIBITORS treatment, unlike in GASTROESOPHAGEAL REFLUX DISEASE. The symptoms are associated with IgE-mediated hypersensitivity to food or inhalant allergens.
Relationships (25)

Relation Types:
diso_​to_​anat : 5
diso_​to_​chem : 3
diso_​to_​diso : 17


Relationships:
none : 10
inheritance_​type_​of : 1
is_​associated_​anatomic_​site_​of : 2
is_​primary_​anatomic_​site_​of_​disease : 1
manifestation_​of : 10
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO42img Complication Aspects C1171258
DISO_to_ANAT36img Esophagus C0014876
DISO_to_ANAT19img eosinophil C0014467
DISO_to_DISO18img Gastroesophageal Reflux C0017168
DISO_to_DISO15img Food Hypersensitivity C0016470
DISO_to_CHEM13img Anti-Inflammatory Agents C0003209
DISO_to_DISO12img Deglutition Disorders C0011168
DISO_to_CHEM8img Androstadienes C0002852
DISO_to_CHEM8img Proton Pump Inhibitors C0358591
DISO_to_DISO8img Eosinophilia C0014457
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Digestive System C0012240
DISO_to_ANATis_associated_anatomic_site_ofimg Esophagus C0014876
DISO_to_ANATis_associated_anatomic_site_ofimg Gastrointestinal system C0012240
DISO_to_DISOmanifestation_ofimg Abdmnal pain epigastric C0232493
DISO_to_DISOmanifestation_ofimg Absence of eosinophilia in other intestinal segments C3277594
DISO_to_DISOmanifestation_ofimg At least 24 eosinophils per high-power field on esophageal biopsy C3277593
DISO_to_DISOmanifestation_ofimg Deglutition Disorders C0011168
DISO_to_DISOpermuted_term_ofimg Eosinophilic esophagitis C0341106
DISO_to_DISOmanifestation_ofimg Failure to Thrive C0015544
DISO_to_DISOmanifestation_ofimg Feeding difficulties C0232466
DISO_to_DISOmanifestation_ofimg Food impaction C3277591
DISO_to_DISOinheritance_type_ofimg Multifactorial C1837655
DISO_to_DISOmanifestation_ofimg Predominantly occurs in young males with high rate of atopic disease C3277595
DISO_to_DISOmanifestation_ofimg Thickening of basal epithelial layer and elongation of papillae C3277592
DISO_to_DISOmanifestation_ofimg Vomiting C0042963
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanCCL2610344chemokine (C-C motif) ligand 26
img GENERIF, Score=1000, Pubmed Id: 16453027, UMLKSK CUI: C0341106
img GENERIF, Score=1000, Pubmed Id: 17900656, UMLKSK CUI: C0341106
HumanIL133596interleukin 13
img GENERIF, Score=1000, Pubmed Id: 18073124, UMLKSK CUI: C0341106
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0341106Eosinophilic esophagitis0self