Human | CD24 | 100133941 | CD24 molecule | |
Human | DAOA | 267012 | D-amino acid oxidase activator | SNP variations in the G72 gene region increase risk of cognitive impairment in schizophrenia |
Human | ANKK1 | 255239 | ankyrin repeat and kinase domain containing 1 | Among the aged with cognitive impairments, the homozygous status for the A2 allele of the DRD2 Taq I polymorphism is associated with diminished cognitive performance and increased atrophy in the striatum |
Human | LRRK2 | 120892 | leucine-rich repeat kinase 2 | |
Human | SPG11 | 80208 | spastic paraplegia 11 (autosomal recessive) | The study reveals the high frequency of SPG11 mutations in patients with HSP, a TCC and cognitive impairment, including in isolated patients, and extends the associated phenotype |
Human | PANK2 | 80025 | pantothenate kinase 2 | |
Human | PCDH19 | 57526 | protocadherin 19 | X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment |
Human | C10orf2 | 56652 | chromosome 10 open reading frame 2 | Cognitive impairment, mild |
Human | APTX | 54840 | aprataxin | We report a patient with homozygous deletion of APTX, who presented with behavioural changes (social withdrawal), and subsequent rapid progression of neurological symptoms associated with severe cognitive decline |
Human | PDE11A | 50940 | phosphodiesterase 11A | |
Human | ATXN10 | 25814 | ataxin 10 | |
Human | NPC2 | 10577 | Niemann-Pick disease, type C2 | Adult-onset NPC2 with lysosomal storage virtually restricted to neurons represents a novel phenotypic and genotypic variant with diffuse cognitive impairment and focal frontal involvement described for the first time |
Human | PLA2G6 | 8398 | phospholipase A2, group VI (cytosolic, calcium-independent) | |
Human | TSC1 | 7248 | tuberous sclerosis 1 | |
Human | SYP | 6855 | synaptophysin | Synaptophysin was absent near neurons bearing clusters of oligomer Abeta, suggesting that accumulated oligomer Abeta, but not fibrillar Abeta, is closely associated with synaptic failure, a major cause of cognitive dysfunction |
Human | SPAST | 6683 | spastin | Title:Subtle cognitive impairment but no dementia in patients with spastin mutations.|Association:Not Found|Conclusion:Asymptomatic cognitive impairment mostly affecting executive functions is present in SPG4 mutation carriers and is more frequent in those with missense mutations. The demonstration of spastin in functionally different brain regions may provide neuroanatomical basis to explain why different brain disorders and cognitive impairment occur in patients with spastin mutation |
Human | SOAT1 | 6646 | sterol O-acyltransferase 1 | Our study confirmed cognitive decline and highly frequent delirium after bypass heart surgery and excluded the possible role of SOAT-1 genotype polymorphisms in their genesis |
Human | SNCA | 6622 | synuclein, alpha (non A4 component of amyloid precursor) | Pathologically confirmed Lewy body disease clinically characterized by progressive parkinsonism and cognitive dysfunction is caused by SNCA duplication |
Human | SLC6A4 | 6532 | solute carrier family 6 (neurotransmitter transporter), member 4 | The presence of STin2.10 and absence of STin2.12 allele may be defined as a possible genetic endophenotype for cognitive dysfunctions detected in MDD The presence of STin2.10 and absence of STin2.12 allele may be related to a possible genetic endophenotype for characteristic cognitive dysfunctions detected in MDD |
Human | SELP | 6403 | selectin P (granule membrane protein 140kDa, antigen CD62) | results suggest a contribution of P-selectin and CRP genes in modulating susceptibility to cognitive decline after cardiac surgery |
Human | SDHA | 6389 | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | |
Human | ATXN7 | 6314 | ataxin 7 | Cognitive dysfunction (rare) |
Human | ATXN1 | 6310 | ataxin 1 | Cognitive impairment, mild |
Human | RPS6KA3 | 6197 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | Expression pattern during development suggests it may be involved in cognitive impairment and facial dysmorphisms found in Coffin-Lowry Syndrome |
Human | PTPRC | 5788 | protein tyrosine phosphatase, receptor type, C | |