Human | CD24 | 100133941 | CD24 molecule | |
Human | DAOA | 267012 | D-amino acid oxidase activator | SNP variations in the G72 gene region increase risk of cognitive impairment in schizophrenia |
Human | ANKK1 | 255239 | ankyrin repeat and kinase domain containing 1 | Among the aged with cognitive impairments, the homozygous status for the A2 allele of the DRD2 Taq I polymorphism is associated with diminished cognitive performance and increased atrophy in the striatum |
Human | LRRK2 | 120892 | leucine-rich repeat kinase 2 | |
Human | SPG11 | 80208 | spastic paraplegia 11 (autosomal recessive) | The study reveals the high frequency of SPG11 mutations in patients with HSP, a TCC and cognitive impairment, including in isolated patients, and extends the associated phenotype |
Human | PANK2 | 80025 | pantothenate kinase 2 | |
Human | PCDH19 | 57526 | protocadherin 19 | X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment |
Human | C10orf2 | 56652 | chromosome 10 open reading frame 2 | Cognitive impairment, mild |
Human | APTX | 54840 | aprataxin | We report a patient with homozygous deletion of APTX, who presented with behavioural changes (social withdrawal), and subsequent rapid progression of neurological symptoms associated with severe cognitive decline |
Human | PDE11A | 50940 | phosphodiesterase 11A | |
Human | ATXN10 | 25814 | ataxin 10 | |
Human | NPC2 | 10577 | Niemann-Pick disease, type C2 | Adult-onset NPC2 with lysosomal storage virtually restricted to neurons represents a novel phenotypic and genotypic variant with diffuse cognitive impairment and focal frontal involvement described for the first time |
Human | PLA2G6 | 8398 | phospholipase A2, group VI (cytosolic, calcium-independent) | |
Human | TSC1 | 7248 | tuberous sclerosis 1 | |
Human | SYP | 6855 | synaptophysin | Synaptophysin was absent near neurons bearing clusters of oligomer Abeta, suggesting that accumulated oligomer Abeta, but not fibrillar Abeta, is closely associated with synaptic failure, a major cause of cognitive dysfunction |
Human | SPAST | 6683 | spastin | The demonstration of spastin in functionally different brain regions may provide neuroanatomical basis to explain why different brain disorders and cognitive impairment occur in patients with spastin mutation Title:Subtle cognitive impairment but no dementia in patients with spastin mutations.|Association:Not Found|Conclusion:Asymptomatic cognitive impairment mostly affecting executive functions is present in SPG4 mutation carriers and is more frequent in those with missense mutations. |
Human | SOAT1 | 6646 | sterol O-acyltransferase 1 | Our study confirmed cognitive decline and highly frequent delirium after bypass heart surgery and excluded the possible role of SOAT-1 genotype polymorphisms in their genesis |
Human | SNCA | 6622 | synuclein, alpha (non A4 component of amyloid precursor) | Pathologically confirmed Lewy body disease clinically characterized by progressive parkinsonism and cognitive dysfunction is caused by SNCA duplication |
Human | SLC6A4 | 6532 | solute carrier family 6 (neurotransmitter transporter), member 4 | The presence of STin2.10 and absence of STin2.12 allele may be defined as a possible genetic endophenotype for cognitive dysfunctions detected in MDD The presence of STin2.10 and absence of STin2.12 allele may be related to a possible genetic endophenotype for characteristic cognitive dysfunctions detected in MDD |
Human | SELP | 6403 | selectin P (granule membrane protein 140kDa, antigen CD62) | results suggest a contribution of P-selectin and CRP genes in modulating susceptibility to cognitive decline after cardiac surgery |
Human | SDHA | 6389 | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | |
Human | ATXN7 | 6314 | ataxin 7 | Cognitive dysfunction (rare) |
Human | ATXN1 | 6310 | ataxin 1 | Cognitive impairment, mild |
Human | RPS6KA3 | 6197 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | Expression pattern during development suggests it may be involved in cognitive impairment and facial dysmorphisms found in Coffin-Lowry Syndrome |
Human | PTPRC | 5788 | protein tyrosine phosphatase, receptor type, C | |