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Details
Link-It Detail - Disease - Hyperplastic Polyp
Debug Stats
  • ### Total Build Time: 28 ms 57.416 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 599 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=3 ms Completed: 3 ms rowSize= 6.076 KB
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 49.206 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hyperplastic Polyp C0333983
Definition (1)
A polyp found mainly in the stomach and colon. Microscopically, it is characterized by elongated, serrated crypts lined by proliferative epithelium. Hyperplastic polyps are traditionally considered non-neoplastic, but ras mutation is common, clonality has been demonstrated and biochemical abnormalities and epidemiological associations that occur in colorectal adenomas and carcinomas have been found (WHO Tumors of the Digestive System, 2000).
Relationships (11)

Relation Types:
diso_​to_​anat : 2
diso_​to_​diso : 9


Relationships:
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 2
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 4
may_​be_​finding_​of_​disease : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Gastrointestinal Tract C0017189
DISO_to_DISOis_not_finding_of_diseaseimg 67 CYTOLOGIC ATYPIAS C0333865
DISO_to_DISOis_not_finding_of_diseaseimg 74 DYSPLASIAS C0334044
DISO_to_DISOisaimg Appendix Hyperplastic Polyp C3272761
DISO_to_DISOisaimg Colorectal HP C1112501
DISO_to_DISOis_finding_of_diseaseimg Exophytic Polypoid Lesion C1514211
DISO_to_DISOisaimg Gallbladder Hyperplastic Polyp C1333743
DISO_to_DISOisaimg Gastric Hyperplastic Polyp C0878649
DISO_to_DISOmay_be_finding_of_diseaseimg Mass of body structure C0577559
DISO_to_DISOis_finding_of_diseaseimg Well-Circumscribed Lesion C1707398
Genes (36)

Species:
human : 36
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMUC3B57876mucin 3B, cell surface associated
img NCI, Score=801, Pubmed Id: 8859775, UMLKSK CUI: C0333983
HumanTRPM754822transient receptor potential cation channel, subfamily M, member 7
img GENERIF, Score=966, Pubmed Id: 17823441, UMLKSK CUI: C0333983
HumanTMEFF223671transmembrane protein with EGF-like and two follistatin-like domains 2
img NCI, Score=801, Pubmed Id: 12460892, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 12384516, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 11120884, UMLKSK CUI: C0333983
HumanAMACR23600alpha-methylacyl-CoA racemase
img NCI, Score=801, Pubmed Id: 14642549, UMLKSK CUI: C0333983
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img NCI, Score=801, Pubmed Id: 15592929, UMLKSK CUI: C0333983
HumanUCP27351uncoupling protein 2 (mitochondrial, proton carrier)
img NCI, Score=801, Pubmed Id: 15448008, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 15448008, UMLKSK CUI: C0333983
HumanTIMP27077TIMP metallopeptidase inhibitor 2
img NCI, Score=801, Pubmed Id: 8918435, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8918435, UMLKSK CUI: C0333983
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 8918435, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8918435, UMLKSK CUI: C0333983
HumanTFF17031trefoil factor 1
img NCI, Score=801, Pubmed Id: 10398119, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8818606, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8818606, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8415590, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 7681255, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8415590, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 8818606, UMLKSK CUI: C0333983
HumanTERC7012telomerase RNA component
img NCI, Score=801, Pubmed Id: 10571509, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 9613120, UMLKSK CUI: C0333983
HumanSTK116794serine/threonine kinase 11
img NCI, Score=801, Pubmed Id: 10740625, UMLKSK CUI: C0333983
HumanSMO6608smoothened, frizzled family receptor
img NCI, Score=801, Pubmed Id: 15258993, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 15258993, UMLKSK CUI: C0333983
HumanSHH6469sonic hedgehog
img NCI, Score=801, Pubmed Id: 15258993, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 15258993, UMLKSK CUI: C0333983
HumanSFRP16422secreted frizzled-related protein 1
img GENERIF, Score=966, Pubmed Id: 15335268, UMLKSK CUI: C0333983
HumanCEACAM64680carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
img NCI, Score=801, Pubmed Id: 10666389, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10666389, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 14512395, UMLKSK CUI: C0333983
HumanMUC64588mucin 6, oligomeric mucus/gel-forming
img GENERIF, Score=1000, Pubmed Id: 18360351, UMLKSK CUI: C0333983
HumanMUC5AC4586mucin 5AC, oligomeric mucus/gel-forming
img NCI, Score=801, Pubmed Id: 9935202, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10424888, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10424888, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10398119, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10398112, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 9935202, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10424888, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 10424888, UMLKSK CUI: C0333983
HumanMUC3A4584mucin 3A, cell surface associated
img NCI, Score=801, Pubmed Id: 8859775, UMLKSK CUI: C0333983
HumanMTAP4507methylthioadenosine phosphorylase
img NCI, Score=801, Pubmed Id: 16224217, UMLKSK CUI: C0333983
HumanMLH14292mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
img GENERIF, Score=966, Pubmed Id: 17160686, UMLKSK CUI: C0333983
HumanMCM24171minichromosome maintenance complex component 2
img NCI, Score=801, Pubmed Id: 16613344, UMLKSK CUI: C0333983
HumanINS3630insulin
img GENERIF, Score=966, Pubmed Id: 18283256, UMLKSK CUI: C0333983
HumanETS22114v-ets avian erythroblastosis virus E26 oncogene homolog 2
img NCI, Score=801, Pubmed Id: 12168840, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 12168840, UMLKSK CUI: C0333983
HumanETS12113v-ets avian erythroblastosis virus E26 oncogene homolog 1
img NCI, Score=801, Pubmed Id: 12168840, UMLKSK CUI: C0333983
img NCI, Score=801, Pubmed Id: 12168840, UMLKSK CUI: C0333983
HumanDUT1854deoxyuridine triphosphatase
img NCI, Score=801, Pubmed Id: 10567908, UMLKSK CUI: C0333983
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0333983Hyperplastic Polyp0self