Human | DYX1C1 | 161582 | dyslexia susceptibility 1 candidate 1 | disequilibrium with DYX1C1 is more saliently explained in Italian dyslexics by short-term memory The observation of weak evidence for transmission disequilibrium for one of the two studied polymorphisms in DYX1C1 suggests involvement of this gene in dyslexia |
Human | UGT1A9 | 54600 | UDP glucuronosyltransferase 1 family, polypeptide A9 | Common polymorphisms do not explain interindividual variation in hepatic UGT1A9 activity/mRNA expression and are in complete linkage disequilibrium in donor liver samples |
Human | USH1C | 10083 | Usher syndrome 1C (autosomal recessive, severe) | USH1C 216G-->A mutation and the 9-repeat VNTR(t,t) allele are in complete linkage disequilibrium in the Acadian population |
Human | CACNA1H | 8912 | calcium channel, voltage-dependent, T type, alpha 1H subunit | Case-control comparisons and the transmission disequilibrium test (TDT) both supported a coding SNP (cSNP) rs9934839 (R603R) in exon 9 as being close related to childhood absence epilepsy |
Human | TNXB | 7148 | tenascin XB | The transmission disequilibrium test did not show allelic association between these two TNXB single nucleotide polymorphisms and schizophrenia, and the rs1009382-rs204887 haplotypes were not associated with the illness either |
Human | SLC6A4 | 6532 | solute carrier family 6 (neurotransmitter transporter), member 4 | Transmission-disequilibrium test of both polymorphisms and haplotype analysis for association with attention deficit hyperactivity disorder fails to detect linkage disequilibrium Transmission disequilibrium mapping at the serotonin transporter gene region in autistic disorder |
Human | SLC6A3 | 6531 | solute carrier family 6 (neurotransmitter transporter), member 3 | No evidence of transmission disequilibrium was detected for alleles of the DAT1 polymorphisms in early onset of obsessive-compulsive disorder |
Human | SHOX | 6473 | short stature homeobox | Crossover clustering and rapid decay of disequilibrium linkage in the Xp/Yp pseudoautosomal gene was studied |
Human | PTH1R | 5745 | parathyroid hormone 1 receptor | haplotype frequencies and linkage disequilibrium (LD) analysis of four different polymorphisms at the PTHR1 locus |
Human | PKLR | 5313 | pyruvate kinase, liver and RBC | PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations |
Human | MYO9B | 4650 | myosin IXB | tested the association between celiac disease and the three most associated single nucleotide polymorphisms by the transmission disequilibrium test in the Italian population |
Human | MTHFR | 4524 | methylenetetrahydrofolate reductase (NAD(P)H) | A strong association of MTHFR polymorphisms and invasive cervical cancer is demonstrated using family-based controls and a transmission/disequilibrium test |
Human | LPL | 4023 | lipoprotein lipase | quantitative-transmission/disequilibrium-test analyses showed that there was linkage between DBP and two single nucleotide polymorphisms in the LPL gene |
Human | IL4R | 3566 | interleukin 4 receptor | No association between type 1 diabetes and any SNP or haplotype was found by the transmission disequilibrium test |
Human | HLA-DRB1 | 3123 | | HLA DRB1*15 was present in 70% of multiple sclerosis affected individuals; the transmission disequilibrium test showed a significant excess in transmission of DRB1*15 alleles to affected individuals The transmission disequilibrium test suggests that HLA-DR4 and DR13 are linked to autism spectrum disorder |
Human | GRIK2 | 2898 | glutamate receptor, ionotropic, kainate 2 | In this study, the maternal transmission disequilibrium of the glutamate receptor GRIK2 in schizophrenia |
Human | GJB2 | 2706 | gap junction protein, beta 2, 26kDa | Detection of disequilibrium between M34T (c.101T>C) and -493del10 in German hearing impaired persons |
Human | CRY1 | 1407 | cryptochrome 1 (photolyase-like) | Linkage disequilibrium analyses using single SNPs and haplotypes showed no association to bipolar disease |
Human | COMT | 1312 | catechol-O-methyltransferase | Transmission disequilibrium test and the haplotype analysis suggested that there was no association between ADHD and the COMT gene in the Chinese population |
Human | CHAT | 1103 | choline O-acetyltransferase | Levels of linkage disequilibrium were generally low across the CHAT locus but two of the coding variants, D7N and A120T, proved to be in complete linkage disequilibrium (late-onset Alzheimer disease) |
Human | AVPR1A | 552 | arginine vasopressin receptor 1A | transmission disequilibrium testing of polymorphism in autism |
Human | ARVCF | 421 | armadillo repeat gene deleted in velocardiofacial syndrome | Two haplotypes covering the catechol-O-methyltransferase-ARVCF region show significant transmission disequilibrium in anorexia nervosa-restricting Israeli-Jewish families |