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Details
Link-It Detail - Disease - Body of Uterus Leiomyosarcoma
Debug Stats
  • ### Total Build Time: 61 ms 44.712 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 356 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 302 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=15 ms Completed: 15 ms rowSize= 14.646 KB
  • CONCEPT_GENES gt=39 ms Completed: 39 ms rowSize= 28.189 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.163 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Body of Uterus Leiomyosarcoma C0280631
Definition (1)
An aggressive malignant smooth muscle neoplasm, arising from the uterine corpus. It is characterized by a proliferation of neoplastic spindle cells.
Relationships (39)

Relation Types:
diso_​to_​anat : 22
diso_​to_​diso : 17


Relationships:
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 4
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 4
is_​not_​finding_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​not_​normal_​tissue_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 2
may_​be_​cytogenetic_​abnormality_​of_​disease : 12
Page Size
Current 25
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Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Body of uterus C0227813
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell of connective tissue C0009781
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell, Smooth Muscle C1135918
DISO_to_ANATis_associated_anatomic_site_ofimg Connective and Soft Tissue C1516798
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_not_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Smooth Muscle Cell C1708909
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Spindle-Shaped Smooth Muscle Cell C1708917
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mature Muscle Cell C0596981
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Muscle C0026845
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Muscle, Smooth C1267092
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Myometrium C0027088
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Connective and Soft Tissue Cell C1513942
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Muscle Cell C1514033
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Nerve Cell, Neuroepithelial Cell, and Supporting Cell of the Nervous System C1518293
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_associated_anatomic_site_ofimg Uterus C0042149
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg soft tissue C0225317
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Additional X Chromosome C1517428
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 1 C1517379
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 15 C1517389
Genes (26)

Species:
human : 26
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanFLCN201163folliculin
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanMLH327030mutL homolog 3 (E. coli)
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanRRAS222800related RAS viral (r-ras) oncogene homolog 2
img NCI, Score=801, Pubmed Id: 7478545, UMLKSK CUI: C0280631
HumanFERMT210979fermitin family member 2
img NCI, Score=801, Pubmed Id: 14745725, UMLKSK CUI: C0280631
HumanAXIN28313axin 2
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanVASP7408vasodilator-stimulated phosphoprotein
img NCI, Score=801, Pubmed Id: 8922250, UMLKSK CUI: C0280631
HumanTP537157tumor protein p53
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanTLR47099toll-like receptor 4
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanTLR27097toll-like receptor 2
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanAURKA6790aurora kinase A
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanPTPRJ5795protein tyrosine phosphatase, receptor type, J
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanPLA2G2A5320phospholipase A2, group IIA (platelets, synovial fluid)
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanPDGFRL5157platelet-derived growth factor receptor-like
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanODC14953ornithine decarboxylase 1
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanNRAS4893neuroblastoma RAS viral (v-ras) oncogene homolog
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanSMAD74092SMAD family member 7
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanLGALS13956lectin, galactoside-binding, soluble, 1
img NCI, Score=801, Pubmed Id: 10230352, UMLKSK CUI: C0280631
HumanGRN2896granulin
img GENERIF, Score=1000, Pubmed Id: 16533762, UMLKSK CUI: C0280631
HumanFH2271fumarate hydratase
img NCI, Score=801, Pubmed Id: 14695314, UMLKSK CUI: C0280631
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanEP3002033E1A binding protein p300
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img GENERIF, Score=884, Pubmed Id: 18156978, UMLKSK CUI: C0280631
HumanBUB1B701BUB1 mitotic checkpoint serine/threonine kinase B
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanAPC324adenomatous polyposis coli
img OMIM, Score=1000, UMLKSK CUI: C0280631
HumanAKT1207v-akt murine thymoma viral oncogene homolog 1
img OMIM, Score=1000, UMLKSK CUI: C0280631
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0280631Body of Uterus Leiomyosarcoma0self