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Details
Link-It Detail - Disease - progesterone receptor negative
Debug Stats
  • ### Total Build Time: 17 ms 26.816 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 358 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 425 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 24.714 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Disease (1)
progesterone receptor negative C0279766
Definition (1)
Describes cells that do not have a protein to which the hormone progesterone will bind. Cancer cells that are progesterone receptor negative do not need progesterone to grow, and usually do not stop growing when treated with hormones that block progesterone from binding.
Genes (21)

Species:
human : 21
SpeciesGeneGeneIdGene NameEvidence
HumanPRDM1663976PR domain containing 16
img GENERIF, Score=694, Pubmed Id: 12816872, UMLKSK CUI: C0279766
HumanSETD8P157108SET domain containing 8 pseudogene 1
img GENERIF, Score=1000, Pubmed Id: 12086618, UMLKSK CUI: C0279766
HumanWWOX51741WW domain containing oxidoreductase
img GENERIF, Score=1000, Pubmed Id: 17947476, UMLKSK CUI: C0279766
HumanTBX2130009T-box 21
img GENERIF, Score=1000, Pubmed Id: 18212358, UMLKSK CUI: C0279766
HumanPRDM27799PR domain containing 2, with ZNF domain
img GENERIF, Score=694, Pubmed Id: 14633678, UMLKSK CUI: C0279766
HumanTFAP2C7022transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
img GENERIF, Score=1000, Pubmed Id: 17947476, UMLKSK CUI: C0279766
HumanSTAT5A6776signal transducer and activator of transcription 5A
img GENERIF, Score=1000, Pubmed Id: 16973758, UMLKSK CUI: C0279766
HumanSOX96662SRY (sex determining region Y)-box 9
img GENERIF, Score=793, Pubmed Id: 17551083, UMLKSK CUI: C0279766
HumanPGR5241progesterone receptor
Click here to display 38 evidence detail records.
HumanNR3C24306nuclear receptor subfamily 3, group C, member 2
img GENERIF, Score=861, Pubmed Id: 14617569, UMLKSK CUI: C0279766
HumanHDAC23066histone deacetylase 2
img GENERIF, Score=1000, Pubmed Id: 18316616, UMLKSK CUI: C0279766
HumanNR3C12908nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
img GENERIF, Score=1000, Pubmed Id: 16973758, UMLKSK CUI: C0279766
HumanGPER2852
img GENERIF, Score=1000, Pubmed Id: 17638621, UMLKSK CUI: C0279766
HumanGATA32625GATA binding protein 3
img GENERIF, Score=1000, Pubmed Id: 18212358, UMLKSK CUI: C0279766
HumanFKBP42288FK506 binding protein 4, 59kDa
img GENERIF, Score=1000, Pubmed Id: 16873445, UMLKSK CUI: C0279766
HumanESR12099estrogen receptor 1
img GENERIF, Score=861, Pubmed Id: 18391223, UMLKSK CUI: C0279766
img GENERIF, Score=660, Pubmed Id: 17006756, UMLKSK CUI: C0279766
img GENERIF, Score=1000, Pubmed Id: 17885486, UMLKSK CUI: C0279766
img GENERIF, Score=1000, Pubmed Id: 18316616, UMLKSK CUI: C0279766
HumanERBB22064v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
img GENERIF, Score=861, Pubmed Id: 17687649, UMLKSK CUI: C0279766
HumanAKR1C21646aldo-keto reductase family 1, member C2
img GENERIF, Score=660, Pubmed Id: 15492289, UMLKSK CUI: C0279766
HumanCSN21447casein beta
img GENERIF, Score=1000, Pubmed Id: 16973758, UMLKSK CUI: C0279766
HumanPRDM1639PR domain containing 1, with ZNF domain
img GENERIF, Score=660, Pubmed Id: 12626569, UMLKSK CUI: C0279766
HumanATM472ataxia telangiectasia mutated
img GENERIF, Score=1000, Pubmed Id: 17982490, UMLKSK CUI: C0279766
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0279766progesterone receptor negative0self