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Details
Link-It Detail - Disease - Cervical Squamous Cell Carcinoma
Debug Stats
  • ### Total Build Time: 42 ms 49.644 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 362 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 753 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=4 ms Completed: 4 ms rowSize= 14.880 KB
  • CONCEPT_GENES gt=25 ms Completed: 25 ms rowSize= 32.438 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cervical Squamous Cell Carcinoma C0279671
Definition (1)
A squamous cell carcinoma arising from the cervical epithelium. It usually evolves from a precancerous cervical lesion. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors for cervical squamous cell carcinoma. The following histologic patterns have been described: Conventional squamous cell carcinoma, papillary squamous cell carcinoma, transitional cell carcinoma, lymphoepithelioma-like carcinoma, verrucous carcinoma, condylomatous carcinoma and spindle cell carcinoma. Survival is most closely related to the stage of disease at the time of diagnosis.
Relationships (37)

Relation Types:
diso_​to_​anat : 19
diso_​to_​diso : 18


Relationships:
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 4
is_​not_​abnormal_​cell_​of_​disease : 3
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 8
may_​be_​cytogenetic_​abnormality_​of_​disease : 2
may_​be_​molecular_​abnormality_​of_​disease : 4
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Cervix Epithelium C1711358
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Cervix Squamous Epithelium C1707351
DISO_to_ANATis_associated_anatomic_site_ofimg Cervix Uteri C0007874
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Squamous Cell C0221910
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Squamous Epithelium C0221909
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Uterus C0042149
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOisaimg Cervical Basaloid Carcinoma C1511063
DISO_to_DISOisaimg Cervical Keratinizing Squamous Cell Carcinoma C1517658
DISO_to_DISOisaimg Cervical Lymphoepithelioma-Like Carcinoma C1516418
DISO_to_DISOisaimg Cervical Non-Keratinizing Squamous Cell Carcinoma C1518366
DISO_to_DISOisaimg Cervical Squamous Cell Carcinoma In Situ C1320453
Genes (138)

Species:
human : 138
Page Size
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SpeciesGeneGeneIdGene NameEvidence
HumanEBF3253738early B-cell factor 3
img GENERIF, Score=972, Pubmed Id: 18559491, UMLKSK CUI: C0279671
HumanNEWENTRY192343Record to support submission of GeneRIFs for a gene not in Gene (human; man).
img GENERIF, Score=972, Pubmed Id: 18798260, UMLKSK CUI: C0279671
HumanSLC5A8160728solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
img GENERIF, Score=972, Pubmed Id: 18559491, UMLKSK CUI: C0279671
HumanGPBAR1151306G protein-coupled bile acid receptor 1
img GENERIF, Score=972, Pubmed Id: 17178880, UMLKSK CUI: C0279671
HumanCD109135228CD109 molecule
img NCI, Score=801, Pubmed Id: 15826242, UMLKSK CUI: C0279671
img NCI, Score=801, Pubmed Id: 15826242, UMLKSK CUI: C0279671
img NCI, Score=801, Pubmed Id: 15826242, UMLKSK CUI: C0279671
HumanIRX179192iroquois homeobox 1
img GENERIF, Score=972, Pubmed Id: 18559491, UMLKSK CUI: C0279671
HumanHPSE260495heparanase 2
img GENERIF, Score=970, Pubmed Id: 15837740, UMLKSK CUI: C0279671
HumanCCNL157018cyclin L1
img GENERIF, Score=972, Pubmed Id: 16598186, UMLKSK CUI: C0279671
HumanEGLN154583egl-9 family hypoxia-inducible factor 1
img GENERIF, Score=972, Pubmed Id: 16489060, UMLKSK CUI: C0279671
HumanDDIT454541DNA-damage-inducible transcript 4
img GENERIF, Score=972, Pubmed Id: 18953439, UMLKSK CUI: C0279671
HumanFXYD553827FXYD domain containing ion transport regulator 5
Click here to display 5 evidence detail records.
HumanPLCE151196phospholipase C, epsilon 1
img GENERIF, Score=743, Pubmed Id: 16565089, UMLKSK CUI: C0279671
HumanCADM123705cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 14970278, UMLKSK CUI: C0279671
HumanARHGEF1223365Rho guanine nucleotide exchange factor (GEF) 12
img GENERIF, Score=743, Pubmed Id: 16565089, UMLKSK CUI: C0279671
HumanRASSF111186Ras association (RalGDS/AF-6) domain family member 1
img GENERIF, Score=972, Pubmed Id: 12082610, UMLKSK CUI: C0279671
HumanSPINK511005serine peptidase inhibitor, Kazal type 5
img GENERIF, Score=970, Pubmed Id: 15680911, UMLKSK CUI: C0279671
HumanSEMA4D10507sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
img GENERIF, Score=970, Pubmed Id: 16754882, UMLKSK CUI: C0279671
HumanAKT310000v-akt murine thymoma viral oncogene homolog 3
img GENERIF, Score=683, Pubmed Id: 15543611, UMLKSK CUI: C0279671
HumanMRC29902mannose receptor, C type 2
img GENERIF, Score=743, Pubmed Id: 17189524, UMLKSK CUI: C0279671
HumanRHOBTB19886Rho-related BTB domain containing 1
img GENERIF, Score=910, Pubmed Id: 16170569, UMLKSK CUI: C0279671
HumanCXCL149547chemokine (C-X-C motif) ligand 14
img NCI, Score=801, Pubmed Id: 10854217, UMLKSK CUI: C0279671
img NCI, Score=801, Pubmed Id: 15843547, UMLKSK CUI: C0279671
HumanSOCS39021suppressor of cytokine signaling 3
img GENERIF, Score=972, Pubmed Id: 16007169, UMLKSK CUI: C0279671
HumanCFLAR8837CASP8 and FADD-like apoptosis regulator
img GENERIF, Score=972, Pubmed Id: 17922291, UMLKSK CUI: C0279671
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
img GENERIF, Score=972, Pubmed Id: 16217763, UMLKSK CUI: C0279671
HumanSOCS18651suppressor of cytokine signaling 1
img GENERIF, Score=741, Pubmed Id: 16432158, UMLKSK CUI: C0279671
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0279671Cervical Squamous Cell Carcinoma0self