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Details
Link-It Detail - Disease - Gastric Adenocarcinoma
Debug Stats
  • ### Total Build Time: 31 ms 55.580 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 873 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=4 ms Completed: 4 ms rowSize= 14.627 KB
  • CONCEPT_GENES gt=25 ms Completed: 25 ms rowSize= 38.540 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Gastric Adenocarcinoma C0278701
Definition (1)
An adenocarcinoma arising from the stomach glandular epithelium. Gastric adenocarcinoma is primarily a disease of older individuals, most commonly develops after a long period of atrophic gastritis and is strongly associated with Helicobacter pylori infection. The lack of early symptoms often delays the diagnosis of gastric cancer. The majority of patients present with advanced tumors which have poor rates of curability. Microscopically, two important histologic types of gastric adenocarcinoma are recognized: the intestinal and diffuse type. The overall prognosis of gastric adenocarcinomas is poor, even in patients who receive a "curative" resection (adapted from Sternberg's Surgical Pathology, 3rd ed., 1999).
Relationships (28)

Relation Types:
diso_​to_​anat : 17
diso_​to_​diso : 11


Relationships:
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 5
may_​be_​finding_​of_​disease : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Adenocarcinoma Cell C1510779
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Gastric Mucosa C0017136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Glandular Cell C1517548
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Glandular Epithelium C0682578
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Stomach C0038351
DISO_to_DISOisaimg Adenocarcinoma of Linitis Plastica Type C0279635
DISO_to_DISOis_not_finding_of_diseaseimg Benign Cellular Infiltrate C1332480
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOmay_be_finding_of_diseaseimg DYSPEPSIA C0013395
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOis_not_finding_of_diseaseimg Mixed Neoplastic Glandular and Squamous Cell Population C1881876
DISO_to_DISOisaimg Siewert type I adenocarcinoma of esophagogastric junction C2585290
DISO_to_DISOisaimg Siewert type II adenocarcinoma of esophagogastric junction C2585795
Genes (143)

Species:
human : 143
Page Size
Current 25
  Page 1 of 6
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMIR27A407018microRNA 27a
img GENERIF, Score=1000, Pubmed Id: 18789835, UMLKSK CUI: C0278701
HumanAMIGO2347902adhesion molecule with Ig-like domain 2
img NCI, Score=801, Pubmed Id: 15107827, UMLKSK CUI: C0278701
HumanGKN2200504gastrokine 2
img GENERIF, Score=983, Pubmed Id: 18593995, UMLKSK CUI: C0278701
HumanPPP1R1B84152protein phosphatase 1, regulatory (inhibitor) subunit 1B
img NCI, Score=801, Pubmed Id: 15363322, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 15363322, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 15363322, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 15363322, UMLKSK CUI: C0278701
HumanREG483998regenerating islet-derived family, member 4
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0278701
HumanMUC3B57876mucin 3B, cell surface associated
img NCI, Score=801, Pubmed Id: 7678777, UMLKSK CUI: C0278701
HumanGKN156287gastrokine 1
img GENERIF, Score=983, Pubmed Id: 18593995, UMLKSK CUI: C0278701
HumanXAF154739XIAP associated factor 1
img GENERIF, Score=983, Pubmed Id: 17471152, UMLKSK CUI: C0278701
HumanPLUNC51297
img GENERIF, Score=913, Pubmed Id: 18204429, UMLKSK CUI: C0278701
HumanA4GNT51146alpha-1,4-N-acetylglucosaminyltransferase
img NCI, Score=801, Pubmed Id: 10430883, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 11304796, UMLKSK CUI: C0278701
HumanSH3GLB151100SH3-domain GRB2-like endophilin B1
img NCI, Score=801, Pubmed Id: 16916719, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 16916719, UMLKSK CUI: C0278701
HumanHTRA227429HtrA serine peptidase 2
img NCI, Score=801, Pubmed Id: 12887511, UMLKSK CUI: C0278701
HumanBBC327113BCL2 binding component 3
img GENERIF, Score=1000, Pubmed Id: 17267315, UMLKSK CUI: C0278701
HumanCKAP226586cytoskeleton associated protein 2
img NCI, Score=801, Pubmed Id: 12942315, UMLKSK CUI: C0278701
HumanMYEOV26579myeloma overexpressed
img GENERIF, Score=1000, Pubmed Id: 16552434, UMLKSK CUI: C0278701
HumanGNL326354guanine nucleotide binding protein-like 3 (nucleolar)
img NCI, Score=801, Pubmed Id: 15112336, UMLKSK CUI: C0278701
HumanTMEFF223671transmembrane protein with EGF-like and two follistatin-like domains 2
img GENERIF, Score=983, Pubmed Id: 12384516, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 12384516, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 12384516, UMLKSK CUI: C0278701
img NCI, Score=801, Pubmed Id: 12384516, UMLKSK CUI: C0278701
HumanPRND23627prion protein 2 (dublet)
img NCI, Score=801, Pubmed Id: 15274317, UMLKSK CUI: C0278701
HumanAMACR23600alpha-methylacyl-CoA racemase
img NCI, Score=801, Pubmed Id: 14506641, UMLKSK CUI: C0278701
HumanIGAD110986immunoglobulin A (IgA) deficiency susceptibility 1
img GENERIF, Score=1000, Pubmed Id: 18202833, UMLKSK CUI: C0278701
HumanNES10763nestin
img NCI, Score=801, Pubmed Id: 12051629, UMLKSK CUI: C0278701
HumanUBE2E310477ubiquitin-conjugating enzyme E2E 3
img NCI, Score=801, Pubmed Id: 10343118, UMLKSK CUI: C0278701
HumanNET110276neuroepithelial cell transforming 1
img GENERIF, Score=1000, Pubmed Id: 16552434, UMLKSK CUI: C0278701
HumanMVP9961major vault protein
img NCI, Score=801, Pubmed Id: 10333409, UMLKSK CUI: C0278701
HumanPTGES9536prostaglandin E synthase
img NCI, Score=801, Pubmed Id: 14520691, UMLKSK CUI: C0278701
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0278701Gastric Adenocarcinoma0self