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Details
Link-It Detail - Disease - Essential Tremor
Debug Stats
  • ### Total Build Time: 75 ms 33.288 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 518 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 554 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 1 ms rowSize= 1.520 KB
  • CONCEPT_RELATIONSHIPS gt=53 ms Completed: 53 ms rowSize= 13.165 KB
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 15.865 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Essential Tremor C0270736
Definition (1)
A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Movement Disorders C0026650
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076824img Movement Disorders C0026650
Relationships (54)

Relation Types:
diso_​to_​anat : 10
diso_​to_​chem : 24
diso_​to_​diso : 16
diso_​to_​gene : 1
diso_​to_​phen : 2
diso_​to_​phys : 1


Relationships:
none : 29
isa : 4
mapped_​to : 1
may_​treat : 19
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO89img Parkinson Disease C0030567
DISO_to_PHEN81img genetic aspects C0017399
DISO_to_DISO56img Parkinson Disease C0030567
DISO_to_DISO55img Complication Aspects C1171258
DISO_to_PHEN44img genetic aspects C0017399
DISO_to_ANAT30img Thalamic structure C0039729
DISO_to_DISO28img Complication Aspects C1171258
DISO_to_ANAT27img Brain C0006104
DISO_to_ANAT24img Thalamic structure C0039729
DISO_to_DISO24img Tremor C0040822
DISO_to_CHEM22img Anticonvulsants C0003286
DISO_to_DISO22img Tremor C0040822
DISO_to_CHEM18img Nerve Tissue Proteins C0027759
DISO_to_PHYS16img GENET PREDISPOSITION C0314657
DISO_to_ANAT15img Ventral Nuclear Group C0228333
DISO_to_CHEM15img Membrane Associated Proteins C0025252
DISO_to_DISO14img Cognition Disorders C0009241
DISO_to_ANAT13img Cerebellum C0007765
DISO_to_DISO13img Dystonia C0013421
DISO_to_ANAT12img Cells, Purkinje C0034143
DISO_to_CHEM12img Anticonvulsants C0003286
DISO_to_GENE11img Polymorphism, Single Nucleotide C0752046
DISO_to_ANAT10img Brain C0006104
DISO_to_ANAT10img In Blood C0005768
DISO_to_CHEM10img Nerve Tissue Proteins C0027759
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanHS1BP364342HCLS1 binding protein 3
img GENERIF, Score=1000, Pubmed Id: 16116142, UMLKSK CUI: C0270736
HumanSNCA6622synuclein, alpha (non A4 component of amyloid precursor)
img GENERIF, Score=1000, Pubmed Id: 12815663, UMLKSK CUI: C0270736
HumanPARK25071parkinson protein 2, E3 ubiquitin protein ligase (parkin)
img GENERIF, Score=694, Pubmed Id: 15261877, UMLKSK CUI: C0270736
HumanFMR12332fragile X mental retardation 1
img GAD, Score=1000, Pubmed Id: 15300658, UMLKSK CUI: C0270736
HumanETM22112essential tremor 2
img GAD, Score=1000, Pubmed Id: 16092108, UMLKSK CUI: C0270736
img GENERIF, Score=1000, Pubmed Id: 15108195, UMLKSK CUI: C0270736
img GAD, Score=1000, Pubmed Id: 15355439, UMLKSK CUI: C0270736
HumanDRD31814dopamine receptor D3
img GENERIF, Score=840, Pubmed Id: 18484990, UMLKSK CUI: C0270736
img OMIM, Score=1000, UMLKSK CUI: C0270736
img GENERIF, Score=1000, Pubmed Id: 16809426, UMLKSK CUI: C0270736
img GENERIF, Score=734, Pubmed Id: 18637033, UMLKSK CUI: C0270736
img GENERIF, Score=1000, Pubmed Id: 18316228, UMLKSK CUI: C0270736
HumanCYP2C91559cytochrome P450, family 2, subfamily C, polypeptide 9
img GENERIF, Score=1000, Pubmed Id: 17627038, UMLKSK CUI: C0270736
HumanAPOB338apolipoprotein B
img GAD, Score=1000, Pubmed Id: 15355439, UMLKSK CUI: C0270736
HumanALAD210aminolevulinate dehydratase
img GAD, Score=1000, Pubmed Id: 15954127, UMLKSK CUI: C0270736
HumanADH1B125alcohol dehydrogenase 1B (class I), beta polypeptide
img GENERIF, Score=1000, Pubmed Id: 17762315, UMLKSK CUI: C0270736
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0270736Essential Tremor0self