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Details
Link-It Detail - Disease - Brain Injuries
Debug Stats
  • ### Total Build Time: 51 ms 57.567 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 326 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 577 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 989 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 3.117 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 5.346 KB
  • CONCEPT_RELATIONSHIPS gt=32 ms Completed: 32 ms rowSize= 13.880 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 32.018 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Brain Injuries C0270611
Definition (1)
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Semantic Types (1)
Injury or Poisoning (T037)
Parents (2)
img Brain Diseases C0006111
img Craniocerebral Trauma C0018674
Children (7)
img Pneumocephalus C0032268
img Shaken Baby Syndrome C0686721
img Diffuse Axonal Injury C0752219
img Epilepsy, Post-Traumatic C0014557
img Brain Hemorrhage, Traumatic C0751799
img Brain Concussion C0006107
img Brain Injury, Chronic C0751813
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076824img Brain Diseases C0006111
img Wounds and Injuries C0043251img Craniocerebral Trauma C00186743img Craniocerebral Trauma C0018674
img Wounds and Injuries C0043251img Trauma, Nervous System C07517924img Craniocerebral Trauma C0018674
img Nervous System Diseases C0027765img Trauma, Nervous System C07517924img Craniocerebral Trauma C0018674
Relationships (290)

Relation Types:
diso_​to_​anat : 42
diso_​to_​chem : 37
diso_​to_​diso : 143
diso_​to_​phen : 5
diso_​to_​phys : 63


Relationships:
none : 283
has_​cdrh_​parent : 2
isa : 1
parent_​is_​cdrh : 1
use : 3
Page Size
Current 25
  Page 1 of 12
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO2248img Complication Aspects C1171258
DISO_to_DISO1450img Complication Aspects C1171258
DISO_to_ANAT683img Brain C0006104
DISO_to_DISO453img Cognition Disorders C0009241
DISO_to_ANAT416img Brain C0006104
DISO_to_ANAT306img In Blood C0005768
DISO_to_DISO296img Cognition Disorders C0009241
DISO_to_CHEM265img Agents, Neuroprotective C0242912
DISO_to_DISO262img Function Recoveries C0599766
DISO_to_ANAT226img Cerebral Cortex C0007776
DISO_to_ANAT197img Neurons C0027882
DISO_to_ANAT181img Neurons C0027882
DISO_to_PHEN172img genetic aspects C0017399
DISO_to_ANAT160img In Blood C0005768
DISO_to_DISO160img Cerebrovascular accident C0038454
DISO_to_ANAT151img Cerebral Cortex C0007776
DISO_to_DISO149img Intracranial Hypertension C0151740
DISO_to_DISO141img Memory Disorders C0025261
DISO_to_PHYS139img Intracranial Pressure C0021880
DISO_to_ANAT135img Hippocampus C0019564
DISO_to_CHEM133img Agents, Neuroprotective C0242912
DISO_to_PHYS128img Cerebrovascular Circulation C0007818
DISO_to_ANAT127img Hippocampus C0019564
DISO_to_PHYS125img Cognition C0009240
DISO_to_PHYS125img ICP - Intracranial pressure C0021880
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanTLR47099toll-like receptor 4
img GENERIF, Score=913, Pubmed Id: 18523439, UMLKSK CUI: C0270611
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img GENERIF, Score=1000, Pubmed Id: 17012236, UMLKSK CUI: C0270611
HumanTGFBI7045transforming growth factor, beta-induced, 68kDa
img GENERIF, Score=1000, Pubmed Id: 12499048, UMLKSK CUI: C0270611
HumanSTC16781stanniocalcin 1
img GENERIF, Score=901, Pubmed Id: 17272771, UMLKSK CUI: C0270611
HumanSLC8A16546solute carrier family 8 (sodium/calcium exchanger), member 1
img GENERIF, Score=861, Pubmed Id: 17912271, UMLKSK CUI: C0270611
HumanS100B6285S100 calcium binding protein B
img GENERIF, Score=913, Pubmed Id: 11809917, UMLKSK CUI: C0270611
img GENERIF, Score=1000, Pubmed Id: 14530578, UMLKSK CUI: C0270611
img GENERIF, Score=901, Pubmed Id: 17020600, UMLKSK CUI: C0270611
img GENERIF, Score=1000, Pubmed Id: 12630517, UMLKSK CUI: C0270611
img GENERIF, Score=901, Pubmed Id: 12351263, UMLKSK CUI: C0270611
img GENERIF, Score=901, Pubmed Id: 18451356, UMLKSK CUI: C0270611
img GENERIF, Score=734, Pubmed Id: 12927678, UMLKSK CUI: C0270611
HumanPRNP5621prion protein
img GENERIF, Score=913, Pubmed Id: 16192387, UMLKSK CUI: C0270611
HumanNOS24843nitric oxide synthase 2, inducible
img GENERIF, Score=694, Pubmed Id: 17065568, UMLKSK CUI: C0270611
HumanNGF4803nerve growth factor (beta polypeptide)
img GENERIF, Score=1000, Pubmed Id: 17881264, UMLKSK CUI: C0270611
HumanMUT4594methylmalonyl CoA mutase
img GENERIF, Score=901, Pubmed Id: 18940555, UMLKSK CUI: C0270611
HumanMPO4353myeloperoxidase
img GENERIF, Score=1000, Pubmed Id: 12818404, UMLKSK CUI: C0270611
HumanMET4233met proto-oncogene
img GENERIF, Score=1000, Pubmed Id: 18628208, UMLKSK CUI: C0270611
HumanMAPT4137microtubule-associated protein tau
INFERRED, Score=800, UMLKSK CUI: C0270611
HumanLEPR3953leptin receptor
img GENERIF, Score=673, Pubmed Id: 18702008, UMLKSK CUI: C0270611
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=901, Pubmed Id: 15466088, UMLKSK CUI: C0270611
HumanHGF3082hepatocyte growth factor (hepapoietin A; scatter factor)
img GENERIF, Score=1000, Pubmed Id: 18628208, UMLKSK CUI: C0270611
HumanGRN2896granulin
img GENERIF, Score=1000, Pubmed Id: 17291356, UMLKSK CUI: C0270611
HumanF13A12162coagulation factor XIII, A1 polypeptide
INFERRED, Score=800, UMLKSK CUI: C0270611
HumanEPO2056erythropoietin
img GENERIF, Score=1000, Pubmed Id: 14747752, UMLKSK CUI: C0270611
img GENERIF, Score=734, Pubmed Id: 15389732, UMLKSK CUI: C0270611
HumanCASP3836caspase 3, apoptosis-related cysteine peptidase
img GENERIF, Score=1000, Pubmed Id: 12867600, UMLKSK CUI: C0270611
HumanCALM2805calmodulin 2 (phosphorylase kinase, delta)
img GENERIF, Score=1000, Pubmed Id: 16545345, UMLKSK CUI: C0270611
HumanAPOE348apolipoprotein E
img GENERIF, Score=901, Pubmed Id: 12638732, UMLKSK CUI: C0270611
img GENERIF, Score=901, Pubmed Id: 17287237, UMLKSK CUI: C0270611
HumanAGT183angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
img GAD, Score=833, Pubmed Id: 11157174, UMLKSK CUI: C0270611
HumanADRB2154adrenoceptor beta 2, surface
img GENERIF, Score=660, Pubmed Id: 18702008, UMLKSK CUI: C0270611
HumanADM133adrenomedullin
img GENERIF, Score=913, Pubmed Id: 15684700, UMLKSK CUI: C0270611
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0270611Brain Injuries0self