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Details
Link-It Detail - Disease - Gastric Dysplasia
Debug Stats
  • ### Total Build Time: 23 ms 39.864 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 454 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=8 ms Completed: 8 ms rowSize= 14.762 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 23.113 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Gastric Dysplasia C0267111
Definition (1)
A intraepithelial neoplasia (dysplasia) that arises in either the native gastric mucosa or in metaplastic gastric epithelium. It has a flat, polypoid or slightly depressed growth pattern. It is graded as low grade (mild dysplasia) or high grade (moderate dysplasia and carcinoma in situ). (WHO, 2000)
Relationships (34)

Relation Types:
diso_​to_​anat : 16
diso_​to_​diso : 18


Relationships:
associated_​with : 1
disease_​has_​associated_​disease : 2
disease_​has_​finding : 2
is_​abnormal_​cell_​of_​disease : 5
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​abnormal_​cell_​of_​disease : 3
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 9
may_​be_​finding_​of_​disease : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Digestive System C0012240
DISO_to_ANATis_abnormal_cell_of_diseaseimg Dysplastic Epithelial Cell C1512100
DISO_to_ANATis_abnormal_cell_of_diseaseimg Dysplastic Glandular Cell C1512104
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Dysplastic Squamous Cell C1512108
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Gastric Glandular Cell C1517451
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Gastric Mucosa C0017136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Glandular Cell C1517548
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Glandular Epithelium C0682578
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Stomach C0038351
DISO_to_DISOassociated_withimg 74 DYSPLASIAS C0334044
DISO_to_DISOdisease_has_findingimg ADENOMATOUS STOMACH POLYP C3146245
DISO_to_DISOisaimg Angiodysplasia of stomach C0744273
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOdisease_has_findingimg Gastric Tubular Adenoma C1333792
DISO_to_DISOdisease_has_associated_diseaseimg Gastric Tubulovillous Adenoma C1333793
DISO_to_DISOdisease_has_associated_diseaseimg Gastric Villous Adenoma C1333794
DISO_to_DISOisaimg High Grade Gastric Intraepithelial Neoplasia C1334004
DISO_to_DISOisaimg Indefinite for Gastric Dysplasia C2987402
Genes (23)

Species:
human : 22
mouse : 1
SpeciesGeneGeneIdGene NameEvidence
MouseCLDN71366claudin 7
img NCI, Score=801, Pubmed Id: 16049341, UMLKSK CUI: C0267111
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 18273500, UMLKSK CUI: C0267111
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanPGC5225progastricsin (pepsinogen C)
img NCI, Score=801, Pubmed Id: 15849808, UMLKSK CUI: C0267111
img NCI, Score=801, Pubmed Id: 15200883, UMLKSK CUI: C0267111
HumanMUTYH4595mutY homolog (E. coli)
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanMUC64588mucin 6, oligomeric mucus/gel-forming
img GENERIF, Score=875, Pubmed Id: 18300795, UMLKSK CUI: C0267111
HumanMUC5AC4586mucin 5AC, oligomeric mucus/gel-forming
img GENERIF, Score=875, Pubmed Id: 18300795, UMLKSK CUI: C0267111
HumanMUC24583mucin 2, oligomeric mucus/gel-forming
img GENERIF, Score=875, Pubmed Id: 18300795, UMLKSK CUI: C0267111
HumanMKI674288antigen identified by monoclonal antibody Ki-67
img GENERIF, Score=901, Pubmed Id: 12434121, UMLKSK CUI: C0267111
HumanKRAS3845Kirsten rat sarcoma viral oncogene homolog
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanIRF13659interferon regulatory factor 1
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanIL1RN3557interleukin 1 receptor antagonist
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanIL1B3553interleukin 1, beta
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanFGFR22263fibroblast growth factor receptor 2
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanERBB22064v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanCTSE1510cathepsin E
img NCI, Score=801, Pubmed Id: 11534800, UMLKSK CUI: C0267111
HumanKLF61316Kruppel-like factor 6
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img GENERIF, Score=1000, Pubmed Id: 15297411, UMLKSK CUI: C0267111
HumanCDH1999cadherin 1, type 1, E-cadherin (epithelial)
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanCASP10843caspase 10, apoptosis-related cysteine peptidase
img OMIM, Score=1000, UMLKSK CUI: C0267111
HumanBCL2596B-cell CLL/lymphoma 2
img GENERIF, Score=964, Pubmed Id: 16246184, UMLKSK CUI: C0267111
HumanBAX581BCL2-associated X protein
img GENERIF, Score=698, Pubmed Id: 16246184, UMLKSK CUI: C0267111
HumanAPC324adenomatous polyposis coli
img OMIM, Score=1000, UMLKSK CUI: C0267111
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0267111Gastric Dysplasia0self