Mouse | CLDN7 | 1366 | claudin 7 | Quantitative real-time reverse transcriptase-polymerase chain reaction and immunohistochemistry showed that Cldn7 was overexpressed in all 10 Tff1-/- gastric dysplasia samples. |
Human | VEGFA | 7422 | vascular endothelial growth factor A | The expression of VEGF in intestinal metaplasia and gastric dysplasia, which could signify an early angiogenic switch during tumorigenesis |
Human | PIK3CA | 5290 | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | |
Human | PGC | 5225 | progastricsin (pepsinogen C) | The positive rates of PGC expression in superficial gastritis or gastric ulcer or erosion, atrophic gastritis or gastric dysplasia and gastric cancer decreased significantly in sequence (P<0.05; 100%/89.2% vs 14.3%/15.2% vs 2.4%). The positive rate of PGC expression decreased in the order of superficial gastritis/gastric ulcer or erosion-->atrophic gastritis or gastric dysplasia-->gastric cancer (P < 0.01). |
Human | MUTYH | 4595 | mutY homolog (E. coli) | |
Human | MUC6 | 4588 | mucin 6, oligomeric mucus/gel-forming | Report MUC6 expression/pathological features of adenomatous and foveolar gastric epithelial dysplasia |
Human | MUC5AC | 4586 | mucin 5AC, oligomeric mucus/gel-forming | Report MUC5AC expression/pathological features of adenomatous and foveolar gastric epithelial dysplasia |
Human | MUC2 | 4583 | mucin 2, oligomeric mucus/gel-forming | Report MUC2 expression/pathological features of adenomatous and foveolar gastric epithelial dysplasia |
Human | MKI67 | 4288 | antigen identified by monoclonal antibody Ki-67 | p53 and Ki-67 expression in epithelial gastric dysplasia and in gastric cancer |
Human | KRAS | 3845 | Kirsten rat sarcoma viral oncogene homolog | |
Human | IRF1 | 3659 | interferon regulatory factor 1 | |
Human | IL1RN | 3557 | interleukin 1 receptor antagonist | |
Human | IL1B | 3553 | interleukin 1, beta | |
Human | FGFR2 | 2263 | fibroblast growth factor receptor 2 | |
Human | ERBB2 | 2064 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 | |
Human | CTSE | 1510 | cathepsin E | The positive staining of cathepsin E decreased with the severity of gastric dysplasia, representing dedifferentiation of the cells. |
Human | KLF6 | 1316 | Kruppel-like factor 6 | |
Human | CDKN2A | 1029 | cyclin-dependent kinase inhibitor 2A | p16 methylation may have a role in the malignant transformation of gastric dysplasia |
Human | CDH1 | 999 | cadherin 1, type 1, E-cadherin (epithelial) | |
Human | CASP10 | 843 | caspase 10, apoptosis-related cysteine peptidase | |
Human | BCL2 | 596 | B-cell CLL/lymphoma 2 | Suppression of Bax and overexpression of Bcl-2 protein is an early event in gastric tumorigenesis, before gastric dysplastic |
Human | BAX | 581 | BCL2-associated X protein | Suppression of Bax and overexpression of Bcl-2 protein is an early event in gastric tumorigenesis, before gastric dysplastic changes occur |
Human | APC | 324 | adenomatous polyposis coli | |