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Details
Link-It Detail - Disease - Adenoma of Parathyroid
Debug Stats
  • ### Total Build Time: 20 ms 49.827 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 573 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 47.604 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adenoma of Parathyroid C0262587
Definition (1)
A benign tumor arising from the parenchymal cells of the parathyroid glands. In the vast majority of cases, the tumor involves a single parathyroid gland. It is associated with the symptoms of primary hyperparathyroidism, resulting from the excessive production of parathyroid hormone. It is usually surrounded by a well-defined capsule. Capsular invasion, vascular invasion, and perineural invasion are absent. (NCI05)
Genes (24)

Species:
human : 24
SpeciesGeneGeneIdGene NameEvidence
HumanPPP1R1B84152protein phosphatase 1, regulatory (inhibitor) subunit 1B
img NCI, Score=801, Pubmed Id: 1663529, UMLKSK CUI: C0262587
HumanCDC7379577cell division cycle 73
img GENERIF, Score=901, Pubmed Id: 15956079, UMLKSK CUI: C0262587
img OMIM, Score=882, UMLKSK CUI: C0262587
HumanGCM29247glial cells missing homolog 2 (Drosophila)
img NCI, Score=801, Pubmed Id: 12354132, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 12354132, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 15657585, UMLKSK CUI: C0262587
HumanSYP6855synaptophysin
img NCI, Score=801, Pubmed Id: 3134611, UMLKSK CUI: C0262587
HumanRET5979ret proto-oncogene
img OMIM, Score=1000, UMLKSK CUI: C0262587
HumanRAD515888RAD51 recombinase
img NCI, Score=801, Pubmed Id: 10583305, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10583305, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10583305, UMLKSK CUI: C0262587
HumanNRGN4900neurogranin (protein kinase C substrate, RC3)
img NCI, Score=801, Pubmed Id: 1660513, UMLKSK CUI: C0262587
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
img OMIM, Score=1000, UMLKSK CUI: C0262587
HumanMEN14221multiple endocrine neoplasia I
img GENERIF, Score=1000, Pubmed Id: 18398822, UMLKSK CUI: C0262587
HumanSMAD34088SMAD family member 3
img NCI, Score=801, Pubmed Id: 12161532, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 12161532, UMLKSK CUI: C0262587
HumanLRP24036low density lipoprotein receptor-related protein 2
img NCI, Score=801, Pubmed Id: 9854589, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10937874, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10937874, UMLKSK CUI: C0262587
HumanIAPP3375islet amyloid polypeptide
img NCI, Score=801, Pubmed Id: 7754100, UMLKSK CUI: C0262587
HumanFGFR22263fibroblast growth factor receptor 2
img NCI, Score=801, Pubmed Id: 10523826, UMLKSK CUI: C0262587
HumanEPOR2057erythropoietin receptor
img GENERIF, Score=1000, Pubmed Id: 18250608, UMLKSK CUI: C0262587
HumanCXADR1525coxsackie virus and adenovirus receptor
img NCI, Score=801, Pubmed Id: 9426434, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10352095, UMLKSK CUI: C0262587
HumanCTNNB11499catenin (cadherin-associated protein), beta 1, 88kDa
img GENERIF, Score=1000, Pubmed Id: 11836555, UMLKSK CUI: C0262587
img GENERIF, Score=1000, Pubmed Id: 17284619, UMLKSK CUI: C0262587
HumanCHGB1114chromogranin B (secretogranin 1)
img NCI, Score=801, Pubmed Id: 2024450, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 2294779, UMLKSK CUI: C0262587
HumanCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
img NCI, Score=801, Pubmed Id: 9286748, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 15009006, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 15009006, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 9286748, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 15009006, UMLKSK CUI: C0262587
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
img NCI, Score=801, Pubmed Id: 8855819, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 8855819, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 8855819, UMLKSK CUI: C0262587
HumanCAV1857caveolin 1, caveolae protein, 22kDa
img NCI, Score=801, Pubmed Id: 12970324, UMLKSK CUI: C0262587
HumanCASR846calcium-sensing receptor
img NCI, Score=801, Pubmed Id: 9426434, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 11889154, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 9854589, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 12656660, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10718832, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10971456, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10971456, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10713061, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10352095, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10718832, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10713061, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10718832, UMLKSK CUI: C0262587
img NCI, Score=801, Pubmed Id: 10713061, UMLKSK CUI: C0262587
HumanBMI1648BMI1 polycomb ring finger oncogene
img NCI, Score=801, Pubmed Id: 16528373, UMLKSK CUI: C0262587
HumanBCL2596B-cell CLL/lymphoma 2
img GENERIF, Score=1000, Pubmed Id: 15800682, UMLKSK CUI: C0262587
HumanCCND1595cyclin D1
img GENERIF, Score=1000, Pubmed Id: 11836555, UMLKSK CUI: C0262587
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0262587Adenoma of Parathyroid0self