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Details
Link-It Detail - Disease - Oxidative Stress
Debug Stats
  • ### Total Build Time: 597 ms 48.093 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 383 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 198 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=486 ms Completed: 486 ms rowSize= 14.713 KB
  • CONCEPT_GENES gt=92 ms Completed: 92 ms rowSize= 31.283 KB
  • CONCEPT_XREFS gt=9 ms Completed: 9 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Oxidative Stress C0242606
Definition (1)
damage to biological tissues caused by superoxide and other free radicals generated as a result of intoxication, antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; do not confuse with HYPOXIA or HYPEROXIA.
Semantic Types (1)
Cell or Molecular Dysfunction (T049)
Relationships (485)

Relation Types:
diso_​to_​anat : 77
diso_​to_​chem : 244
diso_​to_​diso : 93
diso_​to_​gene : 10
diso_​to_​phen : 7
diso_​to_​phys : 54


Relationships:
none : 463
biological_​process_​results_​from_​biological_​process : 3
chemical_​or_​drug_​initiates_​biological_​process : 1
gene_​plays_​role_​in_​process : 10
gene_​product_​plays_​role_​in_​biological_​process : 6
permuted_​term_​of : 1
use : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHYS3969img physiological aspects C0031843
DISO_to_PHYS3026img physiological aspects C0031843
DISO_to_CHEM2475img Antioxidants C0003402
DISO_to_CHEM1280img Antioxidants C0003402
DISO_to_PHYS845img Apoptosis C0162638
DISO_to_PHEN800img genetic aspects C0017399
DISO_to_CHEM735img Reactive Oxygen Species C0162772
DISO_to_DISO592img DNA Damage C0012860
DISO_to_ANAT581img Mitochondria C0026237
DISO_to_ANAT556img Liver C0023884
DISO_to_PHYS499img Apoptosis C0162638
DISO_to_PHYS491img Aging C0001811
DISO_to_DISO489img Inflammation C0021368
DISO_to_CHEM473img Extracts, Plant C0032081
DISO_to_ANAT466img Brain C0006104
DISO_to_ANAT417img Neurons C0027882
DISO_to_DISO388img DNA Damage C0012860
DISO_to_CHEM387img Reactive Oxygen Species C0162772
DISO_to_PHYS337img Signal Transduction C0037083
DISO_to_PHEN331img genetic aspects C0017399
DISO_to_ANAT328img Endothelium, Vascular C0014261
DISO_to_PHYS319img Aging C0001811
DISO_to_PHYS313img Lipid Peroxidation C0023775
DISO_to_ANAT309img Brain C0006104
DISO_to_ANAT307img Mitochondria C0026237
Genes (329)

Species:
human : 329
Page Size
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNCF1C654817neutrophil cytosolic factor 1C pseudogene
img GENERIF, Score=901, Pubmed Id: 16293794, UMLKSK CUI: C0242606
HumanSFTPA1653509surfactant protein A1
img GENERIF, Score=1000, Pubmed Id: 15890661, UMLKSK CUI: C0242606
HumanNCF1653361neutrophil cytosolic factor 1
img GENERIF, Score=901, Pubmed Id: 17478731, UMLKSK CUI: C0242606
HumanLOC648998648998
img GENERIF, Score=1000, Pubmed Id: 17242275, UMLKSK CUI: C0242606
HumanNEIL2252969nei endonuclease VIII-like 2 (E. coli)
img GENERIF, Score=1000, Pubmed Id: 17686777, UMLKSK CUI: C0242606
HumanNEWENTRY192343Record to support submission of GeneRIFs for a gene not in Gene (human; man).
img GENERIF, Score=694, Pubmed Id: 19015244, UMLKSK CUI: C0242606
HumanRDH12145226retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
img GENERIF, Score=861, Pubmed Id: 15865448, UMLKSK CUI: C0242606
HumanDCD117159dermcidin
img GENERIF, Score=1000, Pubmed Id: 18594538, UMLKSK CUI: C0242606
HumanNEIL179661nei endonuclease VIII-like 1 (E. coli)
img GENERIF, Score=694, Pubmed Id: 16118226, UMLKSK CUI: C0242606
HumanSECISBP279048SECIS binding protein 2
img GENERIF, Score=1000, Pubmed Id: 16782878, UMLKSK CUI: C0242606
HumanPINK165018PTEN induced putative kinase 1
img GENERIF, Score=1000, Pubmed Id: 18272063, UMLKSK CUI: C0242606
HumanNGB58157neuroglobin
img GENERIF, Score=673, Pubmed Id: 12860983, UMLKSK CUI: C0242606
HumanHAMP57817hepcidin antimicrobial peptide
img GENERIF, Score=827, Pubmed Id: 18671304, UMLKSK CUI: C0242606
img GENERIF, Score=840, Pubmed Id: 16737972, UMLKSK CUI: C0242606
HumanRETN56729resistin
img GENERIF, Score=861, Pubmed Id: 12829623, UMLKSK CUI: C0242606
HumanOXR155074oxidation resistance 1
img GENERIF, Score=1000, Pubmed Id: 15060142, UMLKSK CUI: C0242606
HumanTMEM161A54929transmembrane protein 161A
img GENERIF, Score=1000, Pubmed Id: 16551573, UMLKSK CUI: C0242606
HumanUGT1A154658UDP glucuronosyltransferase 1 family, polypeptide A1
img GENERIF, Score=901, Pubmed Id: 17259171, UMLKSK CUI: C0242606
HumanUPB151733ureidopropionase, beta
img GENERIF, Score=901, Pubmed Id: 15385443, UMLKSK CUI: C0242606
HumanPIAS451588protein inhibitor of activated STAT, 4
img GENERIF, Score=1000, Pubmed Id: 16906147, UMLKSK CUI: C0242606
HumanIL23A51561interleukin 23, alpha subunit p19
img GENERIF, Score=1000, Pubmed Id: 18606709, UMLKSK CUI: C0242606
HumanANAPC1151529anaphase promoting complex subunit 11
img GENERIF, Score=1000, Pubmed Id: 15256223, UMLKSK CUI: C0242606
HumanGLRX251022glutaredoxin 2
img GENERIF, Score=1000, Pubmed Id: 14676218, UMLKSK CUI: C0242606
HumanNOX450507NADPH oxidase 4
img GENERIF, Score=734, Pubmed Id: 16324151, UMLKSK CUI: C0242606
HumanSENP129843SUMO1/sentrin specific peptidase 1
img GENERIF, Score=1000, Pubmed Id: 17704192, UMLKSK CUI: C0242606
HumanNOX127035NADPH oxidase 1
img GENERIF, Score=1000, Pubmed Id: 16380495, UMLKSK CUI: C0242606
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0242606Oxidative Stress0self