Mouse | CAV1 | 857 | caveolin 1, caveolae protein, 22kDa | Conversely, recombinant expression of Cav-1 in a highly metastatic PyMT mammary carcinoma-derived cell line, namely Met-1 cells, suppressed lung metastasis by approximately 4.5-fold. |
Human | SFTPA2 | 729238 | surfactant protein A2 | These data are consistent with SFTPA2 germline mutations that interfere with protein trafficking and cause familial IPF and lung cancer |
Human | SFTPA1 | 653509 | surfactant protein A1 | Title:|Association:Not Found|Conclusion:Not Found |
Human | MIR126 | 406913 | microRNA 126 | Over-expression of miR126 in a lung cancer cell line resulted in a decrease in Crk protein without any alteration in the associated mRNA |
Human | LOC391533 | 391533 | | Increased soluble VEGFR-1 level is an important parameter in lung cancers |
Human | FRMD3 | 257019 | FERM domain containing 3 | identify FRMD3 as a novel putative tumour suppressor gene suggesting an important role in the origin and progression of lung cancer |
Human | DAB2IP | 153090 | DAB2 interacting protein | Our results demonstrate that hDAB2IP methylation is frequently present in lung cancers and plays a key role in hDAB2IP silencing |
Human | CTCFL | 140690 | CCCTC-binding factor (zinc finger protein)-like | Data indicate that reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter mediates epigenetic regulation of this CT gene in lung cancer cells |
Human | GATA5 | 140628 | GATA binding protein 5 | Hypermethylation of the GATA5 is associated with lung cancer |
Human | ARL11 | 115761 | ADP-ribosylation factor-like 11 | 650 transcripts expressed after restoration of ARLTS1 expression were identified in A549 cells, suggesting that pathways involved in cell survival, proliferation, signaling, and development mediate the effects of wild-type ARLTS1 in lung cancer |
Human | PRKCDBP | 112464 | protein kinase C, delta binding protein | Human SRBC is located within the 11p15.5-p15.4 tumor suppressor region and is inactivated in breast and lung cancers hSRBC is a candidate tumor suppressor gene involved in lung cancer pathogenesis, where expression is frequently inactivated by methylation and other mechanisms |
Human | FAM83A | 84985 | family with sequence similarity 83, member A | Over-expression of BJ-TSA-9 is associated with lung cancer The diagnostic value of BJ-TSA-9 was explored in combination with other known lung cancer markers for the detection of circulating cancer cells in lung cancer patients |
Human | TNS4 | 84951 | tensin 4 | Increased cten mRNA expression was correlated with tumor progression in lung cancers |
Human | MYO18B | 84700 | myosin XVIIIB | candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer |
Human | HDAC10 | 83933 | histone deacetylase 10 | Reduced expression of histone deacetylase 10 is associated lung cancer |
Human | CLPTM1L | 81037 | CLPTM1-like | The susceptibility region contains two genes, TERT and CLPTM1L, suggesting that one or both may have a role in lung cancer etiology |
Human | SUV39H2 | 79723 | suppressor of variegation 3-9 homolog 2 (Drosophila) | a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers |
Human | BIRC7 | 79444 | baculoviral IAP repeat containing 7 | livin gene may play a role in NSCLC development and increased expression of livin mRNA may serve as a new target for lung cancer treatment as well as survivin |
Human | BHLHE41 | 79365 | basic helix-loop-helix family, member e41 | role of the BHLHB3 protein as a tumor suppressor for lung cancer |
Human | PORCN | 64840 | porcupine homolog (Drosophila) | Overexpression of PORCN is associated with lung cancer |
Human | NOD2 | 64127 | nucleotide-binding oligomerization domain containing 2 | NOD2 mutation is associated with breast and lung cancer |
Human | SAMSN1 | 64092 | SAM domain, SH3 domain and nuclear localization signals 1 | downregulation of SAMSN1 gene in human lung cancer |
Human | AHRR | 57491 | aryl-hydrocarbon receptor repressor | None of the polymorphisms were found to play a key role in CYP1A1 inducibility or in the susceptibility to develop lung cancer |
Human | CASC5 | 57082 | cancer susceptibility candidate 5 | a new cancer/testis gene frequently expressed in lung cancer of smokers |
Human | PCBP4 | 57060 | poly(rC) binding protein 4 | expression of alpha CP-4 can inhibit proliferation and tumorigenesis of lung cancer cells, both in vivo and in vitro, by delaying the progression of the cell cycle |