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Details
Link-It Detail - Disease - Neurotoxicity Syndromes
Debug Stats
  • ### Total Build Time: 186 ms 49.747 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 344 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 224 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 986 bytes
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 3.150 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.381 KB
  • CONCEPT_RELATIONSHIPS gt=113 ms Completed: 113 ms rowSize= 13.700 KB
  • CONCEPT_GENES gt=44 ms Completed: 44 ms rowSize= 27.630 KB
  • CONCEPT_XREFS gt=9 ms Completed: 9 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Neurotoxicity Syndromes C0235032
Definition (1)
The tendency of some treatments to cause damage to the nervous system.
Semantic Types (1)
Injury or Poisoning (T037)
Parents (2)
img Nervous System Diseases C0027765
img Poisoning C0032343
Children (7)
img Dyskinesia, Drug-Induced C0013386
img Neuroleptic Malignant Syndrome C0027849
img Heavy Metal Poisoning, Nervous System C0751850
img Alcohol-Induced Disorders, Nervous System C0751865
img MPTP Poisoning C0270730
img Akathisia, Drug-Induced C0162550
img Botulism C0006057
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C00277652img Nervous System Diseases C0027765
img Mental Disorders C0004936img Substance-Related Disorders C02369694img Poisoning C0032343
Relationships (126)

Relation Types:
diso_​to_​anat : 15
diso_​to_​chem : 73
diso_​to_​diso : 33
diso_​to_​phen : 2
diso_​to_​phys : 3


Relationships:
none : 118
is_​associated_​anatomic_​site_​of : 1
isa : 5
permuted_​term_​of : 1
used_​for : 1
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT93img Brain C0006104
DISO_to_CHEM93img Agents, Neuroprotective C0242912
DISO_to_ANAT65img Neurons C0027882
DISO_to_CHEM63img Antineoplastic Agents C0003392
DISO_to_ANAT58img Brain C0006104
DISO_to_DISO55img Complication Aspects C1171258
DISO_to_PHEN51img genetic aspects C0017399
DISO_to_CHEM49img Neurotoxins C0027934
DISO_to_ANAT38img In Blood C0005768
DISO_to_CHEM32img 231-232 INSECTICIDES C0021576
DISO_to_CHEM32img ENVIR POLLUTANTS C0014417
DISO_to_CHEM32img Ecstasy - drug C0115471
DISO_to_CHEM31img Agents, Neuroprotective C0242912
DISO_to_CHEM31img Compounds, Organoplatinum C0029255
DISO_to_CHEM31img Methamphetamine C0025611
DISO_to_DISO31img Occupational Exposure C0028798
DISO_to_DISO31img Oxidative Stress C0242606
DISO_to_ANAT30img Hippocampus C0019564
DISO_to_ANAT30img Neurons C0027882
DISO_to_CHEM29img Cholinesterase Inhibitors C0008425
DISO_to_CHEM28img Neurotoxins C0027934
DISO_to_CHEM26img Antineoplastic Agents C0003392
DISO_to_DISO26img DIS OCCUP C0028797
DISO_to_CHEM25img Antioxidants C0003402
DISO_to_CHEM25img Central Nervous System Stimulants C0002763
Genes (46)

Species:
human : 46
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanANKK1255239ankyrin repeat and kinase domain containing 1
INFERRED, Score=800, UMLKSK CUI: C0235032
HumanTPPP11076tubulin polymerization promoting protein
img GENERIF, Score=1000, Pubmed Id: 18829967, UMLKSK CUI: C0235032
HumanSLC19A210560solute carrier family 19 (thiamine transporter), member 2
INFERRED, Score=800, UMLKSK CUI: C0235032
HumanHYOU110525hypoxia up-regulated 1
img GENERIF, Score=861, Pubmed Id: 17330988, UMLKSK CUI: C0235032
HumanBCL2L1110018BCL2-like 11 (apoptosis facilitator)
img GENERIF, Score=812, Pubmed Id: 17251431, UMLKSK CUI: C0235032
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
img GENERIF, Score=827, Pubmed Id: 18266928, UMLKSK CUI: C0235032
HumanTXN7295thioredoxin
img GENERIF, Score=861, Pubmed Id: 16311508, UMLKSK CUI: C0235032
HumanTTR7276transthyretin
img GENERIF, Score=1000, Pubmed Id: 16114899, UMLKSK CUI: C0235032
HumanTRPC17220transient receptor potential cation channel, subfamily C, member 1
img GENERIF, Score=795, Pubmed Id: 15542611, UMLKSK CUI: C0235032
HumanTKT7086transketolase
INFERRED, Score=800, UMLKSK CUI: C0235032
HumanTH7054tyrosine hydroxylase
INFERRED, Score=800, UMLKSK CUI: C0235032
HumanSOD16647superoxide dismutase 1, soluble
img GENERIF, Score=812, Pubmed Id: 16920710, UMLKSK CUI: C0235032
img GENERIF, Score=789, Pubmed Id: 17555556, UMLKSK CUI: C0235032
HumanSNCA6622synuclein, alpha (non A4 component of amyloid precursor)
img GENERIF, Score=812, Pubmed Id: 18617532, UMLKSK CUI: C0235032
img GENERIF, Score=1000, Pubmed Id: 12042811, UMLKSK CUI: C0235032
HumanSLC6A36531solute carrier family 6 (neurotransmitter transporter), member 3
INFERRED, Score=800, UMLKSK CUI: C0235032
HumanSLC2A16513solute carrier family 2 (facilitated glucose transporter), member 1
img GENERIF, Score=1000, Pubmed Id: 17064664, UMLKSK CUI: C0235032
HumanRYR16261ryanodine receptor 1 (skeletal)
INFERRED, Score=800, UMLKSK CUI: C0235032
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=861, Pubmed Id: 18650379, UMLKSK CUI: C0235032
HumanPRNP5621prion protein
img GENERIF, Score=1000, Pubmed Id: 16537913, UMLKSK CUI: C0235032
HumanMAPK115600mitogen-activated protein kinase 11
img GENERIF, Score=1000, Pubmed Id: 12586546, UMLKSK CUI: C0235032
HumanSEPT45414septin 4
img GENERIF, Score=827, Pubmed Id: 17296554, UMLKSK CUI: C0235032
HumanSEPT55413septin 5
img GENERIF, Score=827, Pubmed Id: 14530399, UMLKSK CUI: C0235032
HumanPARK25071parkinson protein 2, E3 ubiquitin protein ligase (parkin)
img GENERIF, Score=1000, Pubmed Id: 17687034, UMLKSK CUI: C0235032
HumanMMP14312matrix metallopeptidase 1 (interstitial collagenase)
img GENERIF, Score=827, Pubmed Id: 16807369, UMLKSK CUI: C0235032
HumanMAPT4137microtubule-associated protein tau
img GENERIF, Score=812, Pubmed Id: 11959919, UMLKSK CUI: C0235032
HumanHTT3064huntingtin
img GENERIF, Score=861, Pubmed Id: 18504298, UMLKSK CUI: C0235032
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0235032Neurotoxicity Syndromes0self