Human | NDUFS7 | 374291 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | Lesions in basal ganglia, brainstem, cerebellum, thalamus, spinal cord characterized by demyelination, necrosis, gliosis, spongiosis, and capillary proliferation |
Human | IBD9 | 317669 | inflammatory bowel disease 9 | Transmural granulomatous inflammation with 'skip lesions' |
Human | LAMA1 | 284217 | laminin, alpha 1 | mRNA encoding laminin-alpha1, -beta1, and -gamma1 chains was expressed in 90% of endometriotic lesions |
Human | PLA2G4D | 283748 | phospholipase A2, group IVD (cytosolic) | cPLA(2)delta exhibits a unique distribution pattern compared with that of known cPLA(2) subtypes and may play a critical role in inflammation in psoriatic lesions |
Human | NEIL2 | 252969 | nei endonuclease VIII-like 2 (E. coli) | NEIL1 and NEIL2 are preferentially involved in repair of lesions in DNA bubbles generated during transcription and/or replication |
Human | ANO5 | 203859 | anoctamin 5 | Cemento-osseous lesions (maxilla and mandible) |
Human | IBD8 | 170595 | inflammatory bowel disease 8 | Transmural granulomatous inflammation with 'skip lesions' |
Human | FAM84A | 151354 | family with sequence similarity 84, member A | Nse1 RING-like motif is a protein-protein interaction domain required for Smc5-Smc6 holocomplex integrity and recruitment to, or retention at, DNA lesions |
Human | IL23R | 149233 | interleukin 23 receptor | Transmural granulomatous inflammation with 'skip lesions' |
Human | C8orf38 | 137682 | | Lesions in basal ganglia, brainstem, cerebellum, thalamus, spinal cord characterized by demyelination, necrosis, gliosis, spongiosis, and capillary proliferation |
Human | ALKBH2 | 121642 | alkB, alkylation repair homolog 2 (E. coli) | ABH2 is active in the direct reversal of epsilon A lesions, and that ABH2, together with the alkyl-N-adenine-DNA glycosylase, which is the most effective enzyme for the repair of epsilon A, comprise the cellular defense against epsilon A lesions |
Human | C1QTNF5 | 114902 | C1q and tumor necrosis factor related protein 5 | Punctate yellow-white sub-retinal pigment epithelium (RPE) lesions Subnormal focal ERG corresponding to punctate yellow-white sub-RPE lesions |
Human | MYOCD | 93649 | myocardin | HERP1 and myocardin expression was localized to smooth muscle cells in the neointima in human coronary atherosclerotic lesions |
Human | SAMD1 | 90378 | sterile alpha motif domain containing 1 | atherin is present only in atherosclerotic lesions, not in normal intima |
Human | LINGO1 | 84894 | leucine rich repeat and Ig domain containing 1 | the ternary complex of NgR/TROY/LINGO-1 expressed on astrocytes, macrophages/microglia and neurones, by interacting with Nogo-A on oligodendrocytes, might modulate glial-neuronal interactions in demyelinating lesions of multiple sclerosis |
Human | PPP1R1B | 84152 | protein phosphatase 1, regulatory (inhibitor) subunit 1B | The decreased expression of DARPP-32 in oral premalignant and malignant lesions suggests a tumor suppressor role for this protein in the tumorigenesis of these lesions |
Human | CDT1 | 81620 | chromatin licensing and DNA replication factor 1 | Results suggest that DDB1 prevents DNA lesions from accumulating in replicating human cells, in part by regulating Cdt1 degradation |
Human | VTCN1 | 79679 | V-set domain containing T cell activation inhibitor 1 | T-cell and epithelial cell crosstalk-associated B7-H4 induces T-cell activation and is a potential activator that promotes tubular lesion |
Human | SMC6 | 79677 | structural maintenance of chromosomes 6 | Nse1 RING-like motif is a protein-protein interaction domain required for Smc5-Smc6 holocomplex integrity and recruitment to, or retention at, DNA lesions |
Human | NEIL1 | 79661 | nei endonuclease VIII-like 1 (E. coli) | Click here to display 4 evidence detail records. |
Human | NKAP | 79576 | NFKB activating protein | In melanocytic lesions, p16INK4A and NF-kappaB p65 expression were inversely correlated with levels of the nuclear component of NF-kappaB p65 |
Human | XYLT2 | 64132 | xylosyltransferase II | Mucosal PXE lesions (inner aspect lower lip, cheeks, and palate) |
Human | XYLT1 | 64131 | xylosyltransferase I | Mucosal PXE lesions (inner aspect lower lip, cheeks, and palate) |
Human | NOD2 | 64127 | nucleotide-binding oligomerization domain containing 2 | Transmural granulomatous inflammation with 'skip lesions' |
Human | CXCL16 | 58191 | chemokine (C-X-C motif) ligand 16 | Smooth muscle cells express CXCL16 in atherosclerotic lesions, which may play a role in the attraction of T cells to atherosclerotic lesions and contribute to the cellular internalisation of modified LDL This chemokine/scavenger receptor could serve as a molecular link between lipid metabolism and immune activity in the atherosclerotic lesion |