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Details
Link-It Detail - Disease - Paraparesis
Debug Stats
  • ### Total Build Time: 24 ms 30.940 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 320 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 406 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 184 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 543 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 558 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.784 KB
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 11.967 KB
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 13.053 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Paraparesis C0221166
Definition (1)
Mild to moderate loss of bilateral lower extremity motor function, which may be a manifestation of SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; MUSCULAR DISEASES; INTRACRANIAL HYPERTENSION; parasagittal brain lesions; and other conditions.
Semantic Types (1)
Sign or Symptom (T184)
Parents (1)
img Paresis C0030552
Children (1)
img Paraparesis, Spastic C0037771
Ancestral Roots
RootRoot Plus OneDepthParent
img Pathological Conditions, Signs and Symptoms C0039058img Signs and Symptoms C00370885img Paresis C0030552
img Nervous System Diseases C0027765img Neurologic Manifestations C00278544img Paresis C0030552
Relationships (26)

Relation Types:
diso_​to_​anat : 5
diso_​to_​diso : 21


Relationships:
none : 24
isa : 1
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO14img EXTREMITY PARALYSIS, LOWER C0030486
DISO_to_DISO9img Aortic Aneurysm, Thoracic C0162872
DISO_to_ANAT7img Bone structure of thoracic vertebra C0039987
DISO_to_ANAT7img Spinal Cord C0037925
DISO_to_DISO7img Compression of spinal cord C0037926
DISO_to_DISO7img Spinal Cord Ischemia C0752130
DISO_to_ANAT6img Spinal Cord C0037925
DISO_to_DISO6img chemically induced C0007994
DISO_to_DISO5img Aortic Aneurysm, Abdominal C0162871
DISO_to_DISO5img COMPL POSTOP C0032787
DISO_to_DISO5img Compression of spinal cord C0037926
DISO_to_DISO5img Spinal Cord Diseases C0037928
DISO_to_DISO5img Spinal Cord Neoplasms C0037930
DISO_to_DISO5img chemically induced C0007994
DISO_to_ANAT4img Bone structure of lumbar vertebra C0024091
DISO_to_ANAT4img Bone structure of thoracic vertebra C0039987
DISO_to_DISO4img ANEURYSM, DISSECTING C0002949
DISO_to_DISO4img CAT DIS C0007350
DISO_to_DISO4img CNS VASCULAR ANOMALIES C0752155
DISO_to_DISO4img COMPL POSTOP C0032787
DISO_to_DISO4img Spinal Cord Diseases C0037928
DISO_to_DISO4img Spinal Cord Injuries C0037929
DISO_to_DISO4img Spinal Cord Ischemia C0752130
DISO_to_DISO4img Spinal Cord Neoplasms C0037930
DISO_to_DISOisaimg Chronic Progressive Paraparesis C0521663
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanPDB494003Paget disease of bone 4
img OMIM, Score=1000, UMLKSK CUI: C0221166
HumanSPG1180208spastic paraplegia 11 (autosomal recessive)
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanFA2H79152fatty acid 2-hydroxylase
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanGJC257165gap junction protein, gamma 2, 47kDa
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanSPG2151324spastic paraplegia 21 (autosomal recessive, Mast syndrome)
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanSLC25A1510166solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanSQSTM18878sequestosome 1
img OMIM, Score=1000, UMLKSK CUI: C0221166
HumanTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
img OMIM, Score=1000, UMLKSK CUI: C0221166
HumanSPG76687spastic paraplegia 7 (pure and complicated autosomal recessive)
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanSPAST6683spastin
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanSOX106663SRY (sex determining region Y)-box 10
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanPSEN15663presenilin 1
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanNF14763neurofibromin 1
img OMIM, Score=1000, UMLKSK CUI: C0221166
HumanHSPD13329heat shock 60kDa protein 1 (chaperonin)
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanGJB12705gap junction protein, beta 1, 32kDa
img OMIM, Score=1000, UMLKSK CUI: C0221166
HumanGJA12697gap junction protein, alpha 1, 43kDa
img OMIM, Score=1000, UMLKSK CUI: C0221166
HumanGBA2629glucosidase, beta, acid
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanEDNRB1910endothelin receptor type B
INFERRED, Score=800, UMLKSK CUI: C0221166
HumanEDN31908endothelin 3
INFERRED, Score=800, UMLKSK CUI: C0221166
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0221166Paraparesis0self