Human | MIR211 | 406993 | microRNA 211 | expression may be associated with the progression of oral carcinoma and poor patient outcomes |
Human | ORAOV1 | 220064 | oral cancer overexpressed 1 | High-resolution mapping of the 11q13 amplicon and identification of a gene that is amplified and overexpressed in oral cancer cells |
Human | WWOX | 51741 | WW domain containing oxidoreductase | WWOX gene is frequently altered in oral squamous cell carcinomas and may contribute to the carcinogenesis processes in oral cancer |
Human | POSTN | 10631 | periostin, osteoblast specific factor | Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer |
Human | CXCL14 | 9547 | chemokine (C-X-C motif) ligand 14 | results indicate that BRAK/CXCL14 is a chemokine, having suppressive activity toward tumor progression of oral carcinoma in vivo |
Human | CCNA1 | 8900 | cyclin A1 | Significant tumour specific methylation of cyclin A1 promoter seen in oral sqmaous cell carcinoma |
Human | HMGA2 | 8091 | high mobility group AT-hook 2 | HMGA2 overexpression is associated with aggressiveness of oral carcinoma |
Human | XRCC4 | 7518 | X-ray repair complementing defective repair in Chinese hamster cells 4 | Results provide the first evidence that the heterozygous A allele of the XRCC4 codon 247 may be associated with the development of oral cancer combined XRCCs 1-4 polymorphisms associated with oral cancer risk |
Human | XRCC3 | 7517 | X-ray repair complementing defective repair in Chinese hamster cells 3 | Title:Polymorphism in DNA repair genes and oral squamous cell carcinoma in Thailand|Association:Not Found|Conclusion: combined XRCCs 1-4 polymorphisms associated with oral cancer risk |
Human | XRCC2 | 7516 | X-ray repair complementing defective repair in Chinese hamster cells 2 | combined XRCCs 1-4 polymorphisms associated with oral cancer risk |
Human | XRCC1 | 7515 | X-ray repair complementing defective repair in Chinese hamster cells 1 | Title:Polymorphism in DNA repair genes and oral squamous cell carcinoma in Thailand|Association:Not Found|Conclusion: combined XRCCs 1-4 polymorphisms associated with oral cancer risk |
Human | XPC | 7508 | xeroderma pigmentosum, complementation group C | Title:Polymorphism in DNA repair genes and oral squamous cell carcinoma in Thailand|Association:Not Found|Conclusion: Title:Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study formetabolic and DNA repair gene polymorphisms|Association:Not Found|Conclusion: |
Human | XPA | 7507 | xeroderma pigmentosum, complementation group A | Title:Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study formetabolic and DNA repair gene polymorphisms|Association:Not Found|Conclusion: |
Human | VHL | 7428 | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase | Methylation inactivation of vhl is associated with oral cancer |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Title:Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for oral cancer|Association:Y|Conclusion:There is no gender difference in this VEGF gene polymorphism. Therefore, the BstUI polymorphism of the VEGF gene is a suitable genetic marker of oral cancer. High production of VEGF and low production of IL-18 by polymorphonuclear leukocytes of cancer patients may promote neoangiogenesis and may be important for benign tumour cells to acquire metastatic phenotype in the early stage of oral cavity cancer |
Human | TP73 | 7161 | tumor protein p73 | findings suggest that the combined variants of p53 and p73 significantly increase the risk of HPV16-associated oral cancer, especially among never-smokers |
Human | TP53 | 7157 | tumor protein p53 | Click here to display 10 evidence detail records. |
Human | TNF | 7124 | tumor necrosis factor | Title:Association between genetic polymorphism of tumor necrosis factor-alpha and risk of oral submucous fibrosis a pre-cancerous condition of oral cancer.|Association:Y|Conclusion:The finding may imply a multifunctional etiological factor of TNF-alpha in OSF pathogenesis. |
Human | SNAI1 | 6615 | snail family zinc finger 1 | These data show that Snail functions as a molecular mediator of TGF-beta1-regulated MMP-9 expression by increasing Ets-1 and thereby contributing to oral cancer progression |
Human | CXCL12 | 6387 | chemokine (C-X-C motif) ligand 12 | The G801A polymorphism of the SDF-1 gene is associated with advanced stages of oral cancer |
Human | SDC1 | 6382 | syndecan 1 | syndecan-1 directly contributes to the growth and invasive ability of oral cancer cells |
Human | S100A2 | 6273 | S100 calcium binding protein A2 | in oral cancer cells the Ca(2+)- and cell cycle-dependent p53-S100A2 interaction might modulate proliferation |
Human | RB1 | 5925 | retinoblastoma 1 | Data showed that disabling of the Rb pathway was frequent event in oral carcinoma |
Human | PTH1R | 5745 | parathyroid hormone 1 receptor | These data indicate that PTHrP contributes to the malignancy of oral cancers downstream of EGFR signaling, and may thus provide a therapeutic target for oral cancer |
Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | differentiation-inducing agents, particularly sodium butyrate, suppress growth of oral squamous carcinoma cells through apoptosis and induce cell differentiation possibly through mechanisms involving COX-2, p27Kip1 and/or p21WAF1/Cip1 in vitro and in vivo Cytoplasmic expression as well as nuclear translocation of PTGS2 increased with progression of oral cancer expression in oral cancer was found to be independent of grade of tumor and stage of disease Study demonstrates correlation between over expression of NF-kappaB and COX-2 in early precancerous stages of development of oral cancer and sustained elevation down the tumorigenic pathway |