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Details
Link-It Detail - Disease - Adenocarcinoma, Clear Cell
Debug Stats
  • ### Total Build Time: 252 ms 57.741 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 601 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 550 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.499 KB
  • CONCEPT_RELATIONSHIPS gt=175 ms Completed: 175 ms rowSize= 15.052 KB
  • CONCEPT_GENES gt=49 ms Completed: 49 ms rowSize= 38.347 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adenocarcinoma, Clear Cell C0206681
Definition (1)
An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Adenocarcinoma C0001418
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Adenocarcinoma C0001418
Relationships (104)

Relation Types:
diso_​to_​anat : 14
diso_​to_​chem : 9
diso_​to_​diso : 79
diso_​to_​phen : 1
diso_​to_​phys : 1


Relationships:
none : 51
disease_​has_​abnormal_​cell : 23
disease_​may_​have_​abnormal_​cell : 1
is_​abnormal_​cell_​of_​disease : 5
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​finding_​of_​disease : 1
isa : 14
permuted_​term_​of : 1
Page Size
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  Page 1 of 5
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO252img Ovarian Neoplasms C0919267
DISO_to_DISO137img Kidney Neoplasm C0022665
DISO_to_DISO102img Ovarian Neoplasms C0919267
DISO_to_DISO86img Carcinoma, Renal Cell C0007134
DISO_to_PHEN81img genetic aspects C0017399
DISO_to_DISO73img ENDOMETRIAL NEOPL C0014170
DISO_to_DISO71img Cystadenocarcinoma, Serous C0206701
DISO_to_DISO53img Kidney Neoplasm C0022665
DISO_to_DISO41img Carcinoma, Endometrioid C0206687
DISO_to_DISO39img Adenocarcinoma, Mucinous C0007130
DISO_to_CHEM38img Tumor Markers, Biological C0041366
DISO_to_DISO38img Endometriosis C0014175
DISO_to_DISO33img ENDOMETRIAL NEOPL C0014170
DISO_to_DISO32img Complication Aspects C1171258
DISO_to_DISO31img Complication Aspects C1171258
DISO_to_DISO29img Carcinoma, Renal Cell C0007134
DISO_to_DISO26img Neoplasm Recurrence, Local C0027643
DISO_to_CHEM25img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO24img Uterine Cervical Neoplasms C0007873
DISO_to_CHEM20img Antineoplastic Agents C0003392
DISO_to_DISO19img Carcinoma, Endometrioid C0206687
DISO_to_DISO19img MULTIPLE PRIMARY NEOPL C0027663
DISO_to_DISO17img Carcinoma, Papillary C0007133
DISO_to_ANAT16img In Blood C0005768
DISO_to_CHEM16img Proteins, Tumor Suppressor C0597611
Genes (44)

Species:
human : 44
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMAML284441mastermind-like 2 (Drosophila)
img NCI, Score=801, Pubmed Id: 7521153, UMLKSK CUI: C0206681
HumanMUC3B57876mucin 3B, cell surface associated
img NCI, Score=801, Pubmed Id: 12010365, UMLKSK CUI: C0206681
HumanSPA1753340sperm autoantigenic protein 17
img NCI, Score=801, Pubmed Id: 17309563, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 17309563, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 17309563, UMLKSK CUI: C0206681
HumanAMACR23600alpha-methylacyl-CoA racemase
img GENERIF, Score=983, Pubmed Id: 18788852, UMLKSK CUI: C0206681
HumanTACC310460transforming, acidic coiled-coil containing protein 3
img NCI, Score=801, Pubmed Id: 15918899, UMLKSK CUI: C0206681
HumanWFDC210406WAP four-disulfide core domain 2
img NCI, Score=801, Pubmed Id: 15781627, UMLKSK CUI: C0206681
HumanMSLN10232mesothelin
img NCI, Score=801, Pubmed Id: 14576474, UMLKSK CUI: C0206681
HumanABCF210061ATP-binding cassette, sub-family F (GCN20), member 2
img GENERIF, Score=923, Pubmed Id: 16203778, UMLKSK CUI: C0206681
img GENERIF, Score=1000, Pubmed Id: 16996567, UMLKSK CUI: C0206681
HumanFZD57855frizzled family receptor 5
img NCI, Score=801, Pubmed Id: 15557753, UMLKSK CUI: C0206681
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
img GENERIF, Score=906, Pubmed Id: 17555795, UMLKSK CUI: C0206681
img GENERIF, Score=1000, Pubmed Id: 12086860, UMLKSK CUI: C0206681
HumanTP537157tumor protein p53
img GENERIF, Score=923, Pubmed Id: 17581423, UMLKSK CUI: C0206681
HumanTIMP27077TIMP metallopeptidase inhibitor 2
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
img GENERIF, Score=1000, Pubmed Id: 12970394, UMLKSK CUI: C0206681
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 12970394, UMLKSK CUI: C0206681
HumanKLF107071Kruppel-like factor 10
img GENERIF, Score=1000, Pubmed Id: 18359287, UMLKSK CUI: C0206681
HumanHNF1B6928HNF1 homeobox B
img GENERIF, Score=906, Pubmed Id: 18536653, UMLKSK CUI: C0206681
img GENERIF, Score=923, Pubmed Id: 18066692, UMLKSK CUI: C0206681
HumanTACC16867transforming, acidic coiled-coil containing protein 1
img NCI, Score=801, Pubmed Id: 15918899, UMLKSK CUI: C0206681
HumanSPP16696secreted phosphoprotein 1
img GENERIF, Score=923, Pubmed Id: 18393978, UMLKSK CUI: C0206681
HumanSPARC6678secreted protein, acidic, cysteine-rich (osteonectin)
img NCI, Score=801, Pubmed Id: 11679940, UMLKSK CUI: C0206681
HumanMAP2K15604mitogen-activated protein kinase kinase 1
img NCI, Score=801, Pubmed Id: 12644821, UMLKSK CUI: C0206681
HumanMUC3A4584mucin 3A, cell surface associated
img NCI, Score=801, Pubmed Id: 12010365, UMLKSK CUI: C0206681
HumanMUC14582mucin 1, cell surface associated
img GENERIF, Score=983, Pubmed Id: 15489654, UMLKSK CUI: C0206681
HumanMST1R4486macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
img NCI, Score=801, Pubmed Id: 12766581, UMLKSK CUI: C0206681
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 12970394, UMLKSK CUI: C0206681
HumanMITF4286microphthalmia-associated transcription factor
img GENERIF, Score=1000, Pubmed Id: 15884099, UMLKSK CUI: C0206681
HumanEPCAM4072epithelial cell adhesion molecule
img GENERIF, Score=1000, Pubmed Id: 15102668, UMLKSK CUI: C0206681
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206681Adenocarcinoma, Clear Cell0self