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Details
Link-It Detail - Disease - Carcinoma, Embryonal
Debug Stats
  • ### Total Build Time: 214 ms 59.750 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 387 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 476 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 570 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.519 KB
  • CONCEPT_RELATIONSHIPS gt=57 ms Completed: 57 ms rowSize= 14.180 KB
  • CONCEPT_GENES gt=133 ms Completed: 133 ms rowSize= 41.280 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.154 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Carcinoma, Embryonal C0206659
Embryonal Carcinoma
Definition (1)
A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Neoplasms, Germ Cell and Embryonal C0027658
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276524img Neoplasms, Germ Cell and Embryonal C0027658
Relationships (36)

Relation Types:
diso_​to_​anat : 10
diso_​to_​chem : 5
diso_​to_​diso : 16
diso_​to_​phen : 2
diso_​to_​phys : 3


Relationships:
none : 19
eo_​disease_​maps_​to_​human_​disease : 1
is_​abnormal_​cell_​of_​disease : 4
is_​finding_​of_​disease : 4
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
isa : 3
permuted_​term_​of : 1
used_​for : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO40img Testicular Neoplasms C0039590
DISO_to_PHEN23img genetic aspects C0017399
DISO_to_DISO13img Seminoma C0036631
DISO_to_PHYS13img Cell Differentiation C0007589
DISO_to_ANAT12img Stem Cells C0038250
DISO_to_DISO12img SEMINOMA C0036631
DISO_to_PHEN12img genetic aspects C0017399
DISO_to_PHYS12img Cell Differentiation C0007589
DISO_to_ANAT9img Neurons C0027882
DISO_to_CHEM9img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM8img Tretinoin C0040845
DISO_to_DISO8img Germinoma C0206660
DISO_to_ANAT7img Neurons C0027882
DISO_to_CHEM7img TRANSCRIPTION FACTOR C0040648
DISO_to_CHEM7img Transcription Factors C0040648
DISO_to_CHEM7img Tretinoin C0040845
DISO_to_DISO7img Teratoma C0039538
DISO_to_DISO6img Complication Aspects C1171258
DISO_to_PHYS6img GENE EXPRESSION REG NEOPL C0017268
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Germ Cells C0017471
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Germinal Layer C1708239
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Germ Cell C1708878
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Large Germ Cell with Abundant Cytoplasm C1708886
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Germ Cell C1513971
Genes (279)

Species:
human : 226
mouse : 53
Page Size
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SpeciesGeneGeneIdGene NameEvidence
MouseMIR125B2406912microRNA 125b-2
img NCI, Score=801, Pubmed Id: 16227573, UMLKSK CUI: C0206659
MouseMIR125B1406911microRNA 125b-1
img NCI, Score=801, Pubmed Id: 16227573, UMLKSK CUI: C0206659
MouseSIX5147912SIX homeobox 5
img NCI, Score=801, Pubmed Id: 9817928, UMLKSK CUI: C0206659
MouseZFP42132625ZFP42 zinc finger protein
img NCI, Score=801, Pubmed Id: 7798170, UMLKSK CUI: C0206659
MouseSCRT183482scratch homolog 1, zinc finger protein (Drosophila)
img NCI, Score=801, Pubmed Id: 11687288, UMLKSK CUI: C0206659
MouseSTRA664220stimulated by retinoic acid 6
img NCI, Score=801, Pubmed Id: 8792610, UMLKSK CUI: C0206659
img NCI, Score=801, Pubmed Id: 9203140, UMLKSK CUI: C0206659
MouseENAH55740enabled homolog (Drosophila)
img NCI, Score=801, Pubmed Id: 1420303, UMLKSK CUI: C0206659
MouseCEND151286cell cycle exit and neuronal differentiation 1
img NCI, Score=801, Pubmed Id: 10715587, UMLKSK CUI: C0206659
MouseTRIM248805tripartite motif containing 24
img NCI, Score=801, Pubmed Id: 10318760, UMLKSK CUI: C0206659
MouseWNT117481wingless-type MMTV integration site family, member 11
img NCI, Score=801, Pubmed Id: 12167861, UMLKSK CUI: C0206659
img NCI, Score=801, Pubmed Id: 15067007, UMLKSK CUI: C0206659
MouseVCL7414vinculin
img NCI, Score=801, Pubmed Id: 9521841, UMLKSK CUI: C0206659
MouseTTK7272TTK protein kinase
img NCI, Score=801, Pubmed Id: 1375325, UMLKSK CUI: C0206659
MouseTGFB27042transforming growth factor, beta 2
img NCI, Score=801, Pubmed Id: 2797004, UMLKSK CUI: C0206659
img NCI, Score=801, Pubmed Id: 2403946, UMLKSK CUI: C0206659
MouseSPARC6678secreted protein, acidic, cysteine-rich (osteonectin)
img NCI, Score=801, Pubmed Id: 3384223, UMLKSK CUI: C0206659
MouseSOX26657SRY (sex determining region Y)-box 2
img NCI, Score=801, Pubmed Id: 16523502, UMLKSK CUI: C0206659
MouseSAA3P6290serum amyloid A3 pseudogene
img NCI, Score=801, Pubmed Id: 7959007, UMLKSK CUI: C0206659
MouseRXRA6256retinoid X receptor, alpha
img NCI, Score=801, Pubmed Id: 14555536, UMLKSK CUI: C0206659
img NCI, Score=801, Pubmed Id: 9751115, UMLKSK CUI: C0206659
MouseNEUROG14762neurogenin 1
img NCI, Score=801, Pubmed Id: 10648228, UMLKSK CUI: C0206659
MouseNEUROD24761neuronal differentiation 2
img NCI, Score=801, Pubmed Id: 10648228, UMLKSK CUI: C0206659
MouseNDN4692necdin, melanoma antigen (MAGE) family member
img NCI, Score=801, Pubmed Id: 8557705, UMLKSK CUI: C0206659
img NCI, Score=801, Pubmed Id: 1394972, UMLKSK CUI: C0206659
MouseMYOG4656myogenin (myogenic factor 4)
img NCI, Score=801, Pubmed Id: 10915791, UMLKSK CUI: C0206659
MouseMEIS24212Meis homeobox 2
img NCI, Score=801, Pubmed Id: 9337137, UMLKSK CUI: C0206659
MouseMDK4192midkine (neurite growth-promoting factor 2)
img NCI, Score=801, Pubmed Id: 7798170, UMLKSK CUI: C0206659
img NCI, Score=801, Pubmed Id: 8507200, UMLKSK CUI: C0206659
MouseMAPT4137microtubule-associated protein tau
img NCI, Score=801, Pubmed Id: 1560239, UMLKSK CUI: C0206659
MouseSMAD14086SMAD family member 1
img NCI, Score=801, Pubmed Id: 15831466, UMLKSK CUI: C0206659
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206659Carcinoma, Embryonal0self