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Details
Link-It Detail - Disease - Lymphomatoid Papulosis
Debug Stats
  • ### Total Build Time: 178 ms 44.382 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 793 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 563 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 4.090 KB
  • CONCEPT_RELATIONSHIPS gt=114 ms Completed: 114 ms rowSize= 15.944 KB
  • CONCEPT_GENES gt=28 ms Completed: 28 ms rowSize= 21.315 KB
  • CONCEPT_XREFS gt=9 ms Completed: 9 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Lymphomatoid Papulosis C0206182
Definition (1)
A chronic, recurrent cutaneous disorder characterized by the presence of spontaneously regressing papules. The papules are composed of an atypical lymphocytic infiltrate that contains anaplastic CD30-positive T-cells, which are found in type A and diffuse large cell type (type C) lymphomatoid papulosis. In a small number of cases, of type B, the lymphocytic infiltrate is composed of small, cerebriform-like lymphocytes that are often negative for CD30. The majority of cases follow a benign clinical course, but some cases are clonal and may progress to lymphoma. Treatment options include low dose methotrexate and psoralen/UVA (PUVA).
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Lymphoma, T-Cell, Cutaneous C0079773
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210708img Lymphoma, T-Cell, Cutaneous C0079773
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242288img Lymphoma, T-Cell, Cutaneous C0079773
img Neoplasms C0027651img Neoplasms by Histologic Type C00276527img Lymphoma, T-Cell, Cutaneous C0079773
Relationships (53)

Relation Types:
diso_​to_​anat : 22
diso_​to_​chem : 2
diso_​to_​diso : 29


Relationships:
none : 9
associated_​with : 3
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 5
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​normal_​cell_​origin_​of_​disease : 3
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 7
location_​of : 1
may_​be_​associated_​disease_​of_​disease : 3
may_​be_​finding_​of_​disease : 3
may_​be_​molecular_​abnormality_​of_​disease : 2
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO53img Cutaneous tumor C0037286
DISO_to_DISO15img Complication Aspects C1171258
DISO_to_DISO14img Cutaneous tumor C0037286
DISO_to_DISO14img Ki-1+ Anaplastic Large Cell Lymphoma C0206180
DISO_to_DISO11img Complication Aspects C1171258
DISO_to_CHEM10img Antigens, CD30 C0054950
DISO_to_CHEM8img Antigens, CD30 C0054950
DISO_to_DISO8img Ki-1+ Anaplastic Large Cell Lymphoma C0206180
DISO_to_DISO8img Mycosis Fungoides C0026948
DISO_to_ANATis_abnormal_cell_of_diseaseimg Abnormal Hematopoietic and Lymphoid Cell C1510725
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Activated Skin-Homing T-Lymphocyte C1519602
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_associated_anatomic_site_ofimg Integumentary System C0037267
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Lymphatic System C0024235
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lymphatic Tissue C0024296
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Myeloid Cells C0887899
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic B-Lymphocyte C1513929
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Lymphocyte C1514011
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic T-Lymphocyte C1514109
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
img NCI, Score=801, Pubmed Id: 14747305, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 10535446, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 8734569, UMLKSK CUI: C0206182
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12786817, UMLKSK CUI: C0206182
HumanS100A96280S100 calcium binding protein A9
img NCI, Score=801, Pubmed Id: 8305759, UMLKSK CUI: C0206182
HumanNPM14869nucleophosmin (nucleolar phosphoprotein B23, numatrin)
img NCI, Score=801, Pubmed Id: 8781434, UMLKSK CUI: C0206182
HumanJUNB3726jun B proto-oncogene
img NCI, Score=801, Pubmed Id: 15920551, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 15920551, UMLKSK CUI: C0206182
HumanCCR41233chemokine (C-C motif) receptor 4
img NCI, Score=801, Pubmed Id: 16634894, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 16931956, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 12181269, UMLKSK CUI: C0206182
HumanTNFSF8944tumor necrosis factor (ligand) superfamily, member 8
img NCI, Score=801, Pubmed Id: 11594583, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 11594583, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 11594583, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 11121138, UMLKSK CUI: C0206182
HumanTNFRSF8943tumor necrosis factor receptor superfamily, member 8
img GENERIF, Score=1000, Pubmed Id: 12091351, UMLKSK CUI: C0206182
HumanCASP2835caspase 2, apoptosis-related cysteine peptidase
img NCI, Score=801, Pubmed Id: 10777670, UMLKSK CUI: C0206182
img NCI, Score=801, Pubmed Id: 10777670, UMLKSK CUI: C0206182
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206182Lymphomatoid Papulosis0self